T. Shiraki

发表

Ionic Basis of Cold Receptors Acting as Thermostats

K. Takao, A. Hori, Shigeo Kobayashi, 2002, The Journal of Neuroscience.

Acetylation of Histone H2AX at Lys 5 by the TIP60 Histone Acetyltransferase Complex Is Essential for the Dynamic Binding of NBS1 to Damaged Chromatin

K. Furuya, R. Matsuda, J. Adachi, 2015, Molecular and Cellular Biology.

Rational discovery of a novel interface for a coactivator in the peroxisome proliferator‐activated receptor γ: Theoretical implications of impairment in type 2 diabetes mellitus

N. Kamiya, T. Kodama, H. Jingami, 2004, Proteins.

Genomewide approaches for BACH1 target genes in mouse embryonic fibroblasts showed BACH1‐Pparg pathway in adipogenesis

K. Nakayama, N. Yaegashi, H. Katagiri, 2016, Genes to cells : devoted to molecular & cellular mechanisms.

Hemopexin-dependent heme uptake via endocytosis regulates the Bach1 transcription repressor and heme oxygenase gene activation.

K. Igarashi, H. Hada, T. Shiraki, 2014, Biochimica et biophysica acta.

Spectroscopic analyses of the binding kinetics of 15d-PGJ2 to the PPARgamma ligand-binding domain by multi-wavelength global fitting.

T. Kodama, H. Jingami, T. Shiraki, 2006, The Biochemical journal.

The nuclear bile acid receptor FXR is activated by PGC-1alpha in a ligand-dependent manner.

E. Kanaya, H. Jingami, T. Shiraki, 2004, The Biochemical journal.

cDNA cloning and expression of bovine endothelin converting enzyme.

T. Sawamura, K. Tanzawa, S. Kobayashi, 1994, Biochemical and biophysical research communications.

Genetic transfer of endothelin converting enzyme activity to CHO‐K1 cells: detection of positive cells by reverse hemolytic plaque assay

T. Sawamura, T. Masaki, S. Kobayashi, 1994, FEBS letters.

Loosening of Side-Chain Packing Associated with Perturbations in Peripheral Dynamics Induced by the D76N Mutation of β2-Microglobulin Revealed by Pressure-NMR and Molecular Dynamic Simulations

Y. Yonezawa, T. Shiraki, K. Sakurai, 2019, Biomolecules.

Alpha,beta-unsaturated ketone is a core moiety of natural ligands for covalent binding to peroxisome proliferator-activated receptor gamma.

N. Kamiya, T. Kodama, H. Jingami, 2005, The Journal of biological chemistry.

Brain-specific endothelial induction of prostaglandin E2 synthesis enzymes and its temporal relation to fever

K. Yamagata, W. Inoue, T. Takemiya, 2002, Neuroscience Research.

Cyclooxygenase in the vagal afferents: is it involved in the brain prostaglandin response evoked by lipopolysaccharide?

H. Imai, Sohei Kaihatsu, Shigeo Kobayashi, 2000, Autonomic Neuroscience.

Prostaglandin E2 excites neurons of the nucleus tractus solitarius by activating cation channels

H. Onoe, Yasuyoshi Watanabe, Yumiko Watanabe, 1993, Brain Research.

Stimulating effect of 6R-tetrahydrobiopterin on Ca2+ channels in neurons of rat dorsal motor nucleus of the vagus.

T. Masaki, Y. Watanabe, S. Kobayashi, 1996, Biochemical and biophysical research communications.

Endothelin-induced Apoptosis of A375 Human Melanoma Cells*

H. Ninomiya, Shigeo Kobayashi, M. Okazawa, 1998, The Journal of Biological Chemistry.

The nuclear receptor PPARγ individually responds to serotonin‐ and fatty acid‐metabolites

K. Morikawa, Tsuyoshi Waku, R. Nakamori, 2010, The EMBO journal.

Structural insight into PPARgamma activation through covalent modification with endogenous fatty acids.

K. Morikawa, N. Kamiya, H. Jingami, 2009, Journal of molecular biology.

Activation of orphan nuclear constitutive androstane receptor requires subnuclear targeting by peroxisome proliferator-activated receptor gamma coactivator-1 alpha. A possible link between xenobiotic response and nutritional state.

E. Kanaya, H. Jingami, T. Shiraki, 2003, The Journal of biological chemistry.

l‐Menthol‐induced [Ca2+]i increase and impulses in cultured sensory neurons

Shigeo Kobayashi, K. Matsumura, M. Okazawa, 2000, Neuroreport.

Coexpression of Microsomal-Type Prostaglandin E Synthase with Cyclooxygenase-2 in Brain Endothelial Cells of Rats during Endotoxin-Induced Fever

K. Yamagata, Y. Watanabe, W. Inoue, 2001, The Journal of Neuroscience.

α,β-Unsaturated Ketone Is a Core Moiety of Natural Ligands for Covalent Binding to Peroxisome Proliferator-activated Receptor γ*

N. Kamiya, T. Kodama, H. Jingami, 2005, Journal of Biological Chemistry.

Proline cis/trans-Isomerase Pin1 Regulates Peroxisome Proliferator-activated Receptor γ Activity through the Direct Binding to the Activation Function-1 Domain*

K. Morikawa, A. Otaka, Tsuyoshi Waku, 2009, The Journal of Biological Chemistry.

The C113D mutation in human Pin1 causes allosteric structural changes in the phosphate binding pocket of the PPIase domain through the tug of war in the dual-histidine motif.

N. Kobayashi, K. Igarashi, S. Tate, 2014, Biochemistry.

Detecting structural similarity of ligand interactions in the lipid metabolic system including enzymes, lipid-binding proteins and nuclear receptors.

K. Morikawa, T. Shirai, Tsuyoshi Waku, 2011, Protein engineering, design & selection : PEDS.

Phosphorylation of BACH1 switches its function from transcription factor to mitotic chromosome regulator and promotes its interaction with HMMR.

Hiroki Shima, Mitsuyo Matsumoto, K. Igarashi, 2018, The Biochemical journal.

Mechanism of peroxisome proliferator-activated receptor gamma (PPARγ) transactivation by hesperetin glucuronides is distinct from that by a thiazolidine-2,4-dione agent.

N. Matsuura, H. Miyachi, T. Shiraki, 2014, Chemical and pharmaceutical bulletin.

Atomic structure of mutant PPARγ LBD complexed with 15d‐PGJ2: Novel modulation mechanism of PPARγ/RXRα function by covalently bound ligands

K. Morikawa, Tsuyoshi Waku, T. Oyama, 2009, FEBS letters.

Activation of Orphan Nuclear Constitutive Androstane Receptor Requires Subnuclear Targeting by Peroxisome Proliferator-activated Receptor γ Coactivator-1α

E. Kanaya, H. Jingami, T. Shiraki, 2003, Journal of Biological Chemistry.

Hemopexin-dependent heme uptake via endocytosis regulates the Bach1 transcription repressor and heme oxygenase gene activation.

K. Igarashi, H. Hada, T. Shiraki, 2014, Biochimica et biophysica acta.

Structural insight into PPARgamma activation through covalent modification with endogenous fatty acids.

H. Jingami, Tsuyoshi Waku, T. Oyama, 2009 .

The C113D mutation in human Pin1 causes allosteric structural changes in the phosphate binding pocket of the PPIase domain through the tug of war in the dual-histidine motif.

N. Kobayashi, K. Igarashi, S. Tate, 2014, Biochemistry.