J. S. Butler

发表

Chromatin 'resetting' during transcription elongation: a central role for methylated H3K36

Sharon Y. R. Dent, J. S. Butler, 2012, Nature Structural &Molecular Biology.

Protein-arginine Methyltransferase 1 (PRMT1) Methylates Ash2L, a Shared Component of Mammalian Histone H3K4 Methyltransferase Complexes*

Sharon Y. R. Dent, S. Clarke, M. Bedford, 2011, The Journal of Biological Chemistry.

Loss of the N-terminal methyltransferase NRMT1 increases sensitivity to DNA damage and promotes mammary oncogenesis

C. Klinge, Lindsay A. Bonsignore, C. Tooley, 2015, Oncotarget.

Low expression of ASH2L protein correlates with a favorable outcome in acute myeloid leukemia

K. Coombes, Sharon Y. R. Dent, Nianxiang Zhang, 2017, Leukemia & lymphoma.

CFP1 interacts with DNMT1 independently of association with the Setd1 Histone H3K4 methyltransferase complexes.

Jeong-Heon Lee, D. Skalnik, J. S. Butler, 2008, DNA and cell biology.

PAGE separation of hemi-methylated or unmethylated oligonucleotide substrates to distinguish between maintenance and de novo DNA methyltranferase activity.

Jeong-Heon Lee, D. Skalnik, J. S. Butler, 2006, Journal of biochemical and biophysical methods.

New Reasons to Pursue the Therapeutic Potential of Synthetic Nucleic Acids for Neurological Diseases.

M. Napierala, J. S. Butler, 2016, JAMA neurology.

Alleviating GAA Repeat Induced Transcriptional Silencing of the Friedreich's Ataxia Gene During Somatic Cell Reprogramming.

M. Napierala, Yanjie Li, J. S. Butler, 2016, Stem cells and development.

The role of chromatin modifiers in normal and malignant hematopoiesis.

Sharon Y. R. Dent, J. S. Butler, 2013, Blood.

Reduced Genomic Cytosine Methylation and Defective Cellular Differentiation in Embryonic Stem Cells Lacking CpG Binding Protein

D. Skalnik, D. Carlone, Suzanne R. L. Young, 2005, Molecular and Cellular Biology.

Histone-modifying enzymes: regulators of developmental decisions and drivers of human disease.

Sharon Y. R. Dent, J. S. Butler, Evangelia Koutelou, 2012, Epigenomics.

Excision of Expanded GAA Repeats Alleviates the Molecular Phenotype of Friedreich's Ataxia.

M. Napierala, S. Dent, D. Lynch, 2015, Molecular therapy : the journal of the American Society of Gene Therapy.

Selected missense mutations impair frataxin processing in Friedreich ataxia

M. Napierala, D. Lynch, Charles J. Isaacs, 2017, Annals of clinical and translational neurology.

Friedreich's ataxia – a case of aberrant transcription termination?

M. Napierala, J. S. Butler, 2015, Transcription.

Expanded GAA repeats impede transcription elongation through the FXN gene and induce transcriptional silencing that is restricted to the FXN locus.

M. Napierala, D. Lynch, L. Seyer, 2015, Human molecular genetics.

DNA Methyltransferase protein synthesis is reduced in CXXC finger protein 1-deficient embryonic stem cells.

D. Skalnik, R. Wek, J. Sanford, 2009, DNA and cell biology.

Stalled DNA Replication Forks at the Endogenous GAA Repeats Drive Repeat Expansion in Friedreich's Ataxia Cells.

Z. Rosenwaks, P. Dervan, M. Napierala, 2016, Cell reports.

Stalled DNA Replication Fo rks at the Endogenous GAA Repeats Drive Repeat Expansion in Friedreich ’ s Ataxia Cells Graphical

Z. Rosenwaks, P. Dervan, M. Napierala, 2016 .

Identification of a genomic fragment that directs hematopoietic-specific expression of Rac2 and analysis of the DNA methylation profile of the gene locus.

P. Ladd, D. Skalnik, J. S. Butler, 2004, Gene.

Establishment and Maintenance of Primary Fibroblast Repositories for Rare Diseases-Friedreich's Ataxia Example.

M. Napierala, D. Lynch, L. Seyer, 2016, Biopreservation and biobanking.

Stalled DNA Replication Forks at the Endogenous GAA Repeats Drive Repeat Expansion in Friedreich's Ataxia Cells.

Z. Rosenwaks, P. Dervan, M. Napierala, 2016, Cell reports.

Excision of Expanded GAA Repeats Alleviates the Molecular Phenotype of Friedreich's Ataxia.

M. Napierala, S. Dent, D. Lynch, 2015, Molecular therapy : the journal of the American Society of Gene Therapy.