J. Mazella

发表

Neurotensin-induced Erk1/2 phosphorylation and growth of human colonic cancer cells are independent from growth factors receptors activation.

A. Tormo, F. Massa, S. Béraud-Dufour, 2011, Biochemical and biophysical research communications.

Regulation of cyclic GMP levels by neurotensin in neuroblastoma clone N1E115.

F. Checler, P. Kitabgi, J. Vincent, 1985, Biochemical and biophysical research communications.

Sustained neurotensin exposure promotes cell surface recruitment of NTS2 receptors.

A. Beaudet, N. Sharif, A. Perron, 2006, Biochemical and biophysical research communications.

Spadin, a Sortilin-Derived Peptide, Targeting Rodent TREK-1 Channels: A New Concept in the Antidepressant Drug Design

E. Chevet, G. Gobbi, O. Pétrault, 2010, PLoS biology.

Neurotensin is a regulator of insulin secretion in pancreatic beta-cells.

G. Waeber, A. Abderrahmani, F. Brau, 2010, The international journal of biochemistry & cell biology.

Differential internalization of somatostatin in COS-7 cells transfected with SST1 and SST2 receptor subtypes: a confocal microscopic study using novel fluorescent somatostatin derivatives.

A. Beaudet, T. Reisine, G. Gaudriault, 1997, Endocrinology.

Differential Internalization of Somatostatin in COS-7 Cells Transfected with SST1 and SST2 Receptor Subtypes: A Confocal Microscopic Study Using Novel Fluorescent Somatostatin Derivatives1.

A. Beaudet, T. Reisine, G. Gaudriault, 1997, Endocrinology.

Receptor-mediated Internalization Is Critical for the Inhibition of the Expression of Growth Hormone by Somatostatin in the Pituitary Cell Line AtT-20*

A. Beaudet, P. Sarret, J. Vincent, 1999, The Journal of Biological Chemistry.

Pharmacology and biochemistry of neurotensin receptors.

F. Checler, P. Kitabgi, J. Vincent, 1985, Reviews in clinical & basic pharmacology.

Preparation of neurotensin selectively iodinated on the tyrosine 3 residue. Biological activity and binding properties on mammalian neurotensin receptors.

P. Kitabgi, J. Vincent, J. Mazella, 1984, Biochemical and biophysical research communications.

Solubilization and purification of a high affinity neurotensin receptor from newborn human brain

J. Vincent, N. Zsürger, J. Mazella, 1994, Brain Research.

Functional properties and molecular structure of central and peripheral neurotensin receptors.

P. Kitabgi, J. Vincent, J. Mazella, 1987, Journal of receptor research.

Covalent labeling of neurotensin receptors in rat gastric fundus plasma membranes

P. Kitabgi, J. Vincent, C. Kwan, 1985, Peptides.

Monoiodo-[Trp11]neurotensin, a highly radioactive ligand of neurotensin receptors. Preparation, biological activity, and binding properties to rat brain synaptic membranes.

C. Granier, F. Checler, P. Kitabgi, 1983, The Journal of biological chemistry.

Internalization and trafficking of neurotensin via NTS3 receptors in HT29 cells.

A. Beaudet, Stéphane Martin, J. Vincent, 2004, The international journal of biochemistry & cell biology.

Distribution of NTS3 receptor/sortilin mRNA and protein in the rat central nervous system

A. Beaudet, P. Sarret, T. Stroh, 2003, The Journal of comparative neurology.

β‐Arrestin is involved in the desensitization but not in the internalization of the somatostatin receptor 2A expressed in CHO cells

J. Vincent, J. Mazella, Sabrina Brasselet, 2002, FEBS letters.

Increased Brain Neurotensin and NTSR2 Lead to Weak Nociception in NTSR3/Sortilin Knockout Mice

C. Morales, T. Dix, J. Mazella, 2016, Front. Neurosci..

Crucial Role of Neuron-enriched Endosomal Protein of 21 kDa in Sorting between Degradation and Recycling of Internalized G-protein-coupled Receptors*

P. Steiner, H. Hirling, J. Vincent, 2004, Journal of Biological Chemistry.

Coexpression of somatostatin receptor subtype 5 affects internalization and trafficking of somatostatin receptor subtype 2.

A. Beaudet, N. Sharif, L. Gendron, 2007, Endocrinology.

High‐Affinity Receptor Sites and Rapid Proteolytic Inactivation of Neurotensin in Primary Cultured Neurons

F. Checler, P. Kitabgi, J. Vincent, 1986, Journal of neurochemistry.

High‐Affinity Neurotensin Binding Sites in Differentiated Neuroblastoma N1E115 Cells

P. Kitabgi, J. Vincent, J. Mazella, 1984, Journal of neurochemistry.

A Human TREK-1/HEK Cell Line: A Highly Efficient Screening Tool for Drug Development in Neurological Diseases

R. Peyronnet, C. Heurteaux, C. Gandin, 2011, PloS one.

Thr-422 and Tyr-424 Residues in the Carboxyl Terminus Are Critical for the Internalization of the Rat Neurotensin Receptor (*)

A. Beaudet, J. Vincent, D. Nouel, 1995, The Journal of Biological Chemistry.

Ligand-induced internalization of neurotensin in transfected COS-7 cells: differential intracellular trafficking of ligand and receptor.

A. Beaudet, F. Vandenbulcke, J. Vincent, 2000, Journal of cell science.

Contulakin-G, an O-Glycosylated Invertebrate Neurotensin*

B. Olivera, E. Richelson, Karsten Schmidt, 1999, The Journal of Biological Chemistry.

Colocalization of neurotensin receptors and of the neurotensin- degrading enzyme endopeptidase 24-16 in primary cultures of neurons

F. Checler, J. Vincent, J. Chabry, 1990, The Journal of neuroscience : the official journal of the Society for Neuroscience.

Internalization and recycling properties of neurotensin receptors

J. Vincent, J. Mazella, 2006, Peptides.

Neurotensin receptor-1 and -3 complex modulates the cellular signaling of neurotensin in the HT29 cell line.

Stéphane Martin, J. Vincent, J. Mazella, 2002, Gastroenterology.

[3H]SR 48692, the first nonpeptide neurotensin antagonist radioligand: characterization of binding properties and evidence for distinct agonist and antagonist binding domains on the rat neurotensin receptor.

M. Mas, D. Gully, P. Kitabgi, 1995, Molecular pharmacology.

Retroinverso analogs of spadin display increased antidepressant effects

C. Heurteaux, G. Gaudriault, H. Moha ou Maati, 2014, Psychopharmacology.

Deciphering Mechanisms of Action of Sortilin/Neurotensin Receptor-3 in the Proliferation Regulation of Colorectal and Other Cancers

J. Mazella, 2022, International journal of molecular sciences.

Sortilin-derived peptides promote pancreatic beta-cell survival through CREB signaling pathway.

P. Lebrun, A. Abderrahmani, C. Heurteaux, 2021, Pharmacological research.

Potentiation of Calcium Influx and Insulin Secretion in Pancreatic Beta Cell by the Specific TREK-1 Blocker Spadin

A. Abderrahmani, C. Heurteaux, H. Moha ou Maati, 2016, Journal of diabetes research.

Somatostatin, Growth Hormone-Releasing Hormone

A. Beaudet, P. Sarret, J. Vincent, 1998 .

Neurotensin protects pancreatic beta cells from apoptosis.

J. Vincent, S. Béraud-Dufour, T. Coppola, 2008, The international journal of biochemistry & cell biology.

Intracellular Dynamics of sst5 Receptors in Transfected COS-7 Cells: Maintenance of Cell Surface Receptors during Ligand-Induced Endocytosis1.

A. Beaudet, P. Sarret, A. C. Jackson, 2000, Endocrinology.

Intracellular dynamics of sst5 receptors in transfected COS-7 cells: maintenance of cell surface receptors during ligand-induced endocytosis.

A. Beaudet, P. Sarret, A. C. Jackson, 2000, Endocrinology.

Spadin, a Sortilin-derived peptide: a new concept in the antidepressant drug design

S. Antipolis, C. Heurteaux, J. Mazella, 2011 .

Neurotensin receptor‐3/sortilin mediates neurotensin‐induced cytokine/chemokine expression in a murine microglial cell line

E. Dicou, J. Vincent, J. Mazella, 2004, Journal of neuroscience research.

Identification and characterization of two zebrafish Twik related potassium channels, Kcnk2a and Kcnk2b

C. Jopling, C. Heurteaux, A. Faucherre, 2018, Scientific Reports.

The Anti-Apoptotic Role of Neurotensin

S. Béraud-Dufour, T. Coppola, J. Mazella, 2013, Cells.

Neurotensin receptor-2 and -3 are crucial for the anti-apoptotic effect of neurotensin on pancreatic beta-TC3 cells.

F. Massa, S. Béraud-Dufour, T. Coppola, 2009, The international journal of biochemistry & cell biology.

Solubilization and characterization of active neurotensin receptors from mouse brain.

P. Kitabgi, J. Vincent, J. Chabry, 1988, The Journal of biological chemistry.

THE CONCISE GUIDE TO PHARMACOLOGY 2021/22: G protein‐coupled receptors

Stephen P. H. Alexander, Leigh A. Stoddart, Kalyan C. Tirupula, 2021, British journal of pharmacology.

Internalization and intracellular mobilization of neurotensin in neuronal cells.

A. Beaudet, P. Kitabgi, M. Castel, 1994, Biochemical pharmacology.

Neurotensin and neurotensin receptors.

J P Vincent, P. Kitabgi, J Mazella, 1999, Trends in pharmacological sciences.

Identification of the Receptor Subtype Involved in the Analgesic Effect of Neurotensin

J. Costentin, P. Kitabgi, E. Honoré, 1999, The Journal of Neuroscience.

Neurotensin and the neurotensin receptor‐3 in microglial cells

Stéphane Martin, E. Dicou, J. Vincent, 2005, Journal of neuroscience research.

Sortilin/neurotensin receptor-3: a new tool to investigate neurotensin signaling and cellular trafficking?

J. Mazella, 2001, Cellular signalling.

Molecular Sciences Focal Adhesion Kinase-dependent Role of the Soluble Form of Neurotensin Receptor-3/sortilin in Colorectal Cancer Cell Dissociation

F. Massa, S. Béraud-Dufour, T. Coppola, 2022 .

Functional roles of the NTS2 and NTS3 receptors

J. Vincent, J. Mazella, 2006, Peptides.

Involvement of the neurotensin receptor subtype NTR3 in the growth effect of neurotensin on cancer cell lines

P. Sarret, J. Vincent, J. Mazella, 2001, International journal of cancer.

Involvement of the Neurotensin Receptor-3 in the Neurotensin-Induced Migration of Human Microglia

Stéphane Martin, J. Vincent, J. Mazella, 2003, The Journal of Neuroscience.

Pharmacological properties of the mouse neurotensin receptor 3. Maintenance of cell surface receptor during internalization of neurotensin

P. Sarret, C. M. Petersen, M. Nielsen, 2001, FEBS letters.

The 100-kDa Neurotensin Receptor Is gp95/Sortilin, A Non-G-Protein-coupled Receptor*

M. Kaghad, P. Ferrara, D. Caput, 1998, The Journal of Biological Chemistry.

Structure, Functional Expression, and Cerebral Localization of the Levocabastine-Sensitive Neurotensin/Neuromedin N Receptor from Mouse Brain

Philippe Sarret, P. Sarret, E. Guillemare, 1996, The Journal of Neuroscience.

Stable Expression of the Cloned Rat Brain Neurotensin Receptor into Fibroblasts: Binding Properties, Photoaffinity Labeling, Transduction Mechanisms, and Internalization

P. Kitabgi, J. Vincent, J. Chabry, 1994, Journal of neurochemistry.

Impairement of HT29 Cancer Cells Cohesion by the Soluble Form of Neurotensin Receptor-3

S. Lacas‐Gervais, F. Massa, S. Béraud-Dufour, 2014, Genes & cancer.

The Involvement of Sortilin/NTSR3 in Depression as the Progenitor of Spadin and Its Role in the Membrane Expression of TREK-1

C. Heurteaux, J. Mazella, M. Borsotto, 2019, Front. Pharmacol..

Focal adhesion kinase dependent activation of the PI3 kinase pathway by the functional soluble form of neurotensin receptor-3 in HT29 cells.

F. Brau, F. Massa, S. Béraud-Dufour, 2013, The international journal of biochemistry & cell biology.

Neurotensin and its receptors in the control of glucose homeostasis

F. Massa, S. Béraud-Dufour, T. Coppola, 2012, Front. Endocrin..

Stable expression of the mouse levocabastine-sensitive neurotensin receptor in HEK 293 cell line: binding properties, photoaffinity labeling, and internalization mechanism.

P. Sarret, J. Vincent, J. Chabry, 1998, Biochemical and biophysical research communications.

Implication of various forms of neurotensin receptors in the mechanism of internalization of neurotensin in cerebral neurons.

G. Gaudriault, J. Vincent, J. Chabry, 1993, The Journal of biological chemistry.

Purification of the neurotensin receptor from mouse brain by affinity chromatography.

J. Vincent, J. Chabry, J. Mazella, 1989, The Journal of biological chemistry.

Neurotensin receptors (version 2019.4) in the IUPHAR/BPS Guide to Pharmacology Database

P. Sarret, J. Vincent, J. Mazella, 2019, IUPHAR/BPS Guide to Pharmacology CITE.

Internalization-dependent regulation of HT29 cell proliferation by neurotensin

Stéphane Martin, J. Mazella, V. Navarro, 2006, Peptides.

Recycling ability of the mouse and the human neurotensin type 2 receptors depends on a single tyrosine residue.

Stéphane Martin, Jean-Pierre Vincent, J. Vincent, 2002, Journal of cell science.

Pivotal role of an aspartate residue in sodium sensitivity and coupling to G proteins of neurotensin receptors.

J. Vincent, J. Mazella, J. Botto, 1999, Molecular pharmacology.

Existence of two translation initiation sites leading to the expression of two proteins from the rat high-affinity neurotensin-receptor cDNA: possible regulation by the 5' end non-coding region.

J. Vincent, J. Mazella, J. Botto, 1997, The Biochemical journal.

Sortilin/neurotensin receptor-3 and its derived peptides in depression

C. Heurteaux, J. Mazella, M. Borsotto, 2021 .

Fighting against depression with TREK‐1 blockers: Past and future. A focus on spadin

M. Pietri, C. Heurteaux, J. Mazella, 2019, Pharmacology & therapeutics.

Shedding of the luminal domain of the neurotensin receptor-3/sortilin in the HT29 cell line.

J. Vincent, J. Mazella, V. Navarro, 2002, Biochemical and biophysical research communications.

Pharmacological, molecular and functional characterization of glial neurotensin receptors

A. Beaudet, P. Sarret, D. Nouel, 1999, Neuroscience.

Molecular properties of neurotensin receptors in rat brain. Identification of subunits by covalent labeling.

P. Kitabgi, J. Vincent, J. Mazella, 1985, The Journal of biological chemistry.

Porcine odorant-binding protein selectively binds to a human olfactory receptor.

Jacques Demaille, M. Crowe, J. Demaille, 2002, Chemical senses.

Neurotensin Receptors in Primary Culture of Neurons

A. Beaudet, F. Checler, J. Vincent, 1993 .

Internalization of Neurotensin in Cultured Neurons

A. Beaudet, P. Kitabgi, J. Chabry, 1992, Annals of the New York Academy of Sciences.

Binding and internalization of iodinated neurotensin in neuronal cultures from embryonic mouse brain

A. Beaudet, P. Kitabgi, J. Vincent, 1991, Brain Research.

Somatostatin-Induced Regulation of SST2A Receptor Expression and Cell Surface Availability in Central Neurons: Role of Receptor Internalization

A. Beaudet, H. Boudin, P. Sarret, 2000, The Journal of Neuroscience.

Design, synthesis, and evaluation of the antipsychotic potential of orally bioavailable neurotensin (8–13) analogues containing non-natural arginine and lysine residues

M. K. Hadden, K. Kokko, T. Dix, 2005, Neuropharmacology.

Mutagenesis and Modeling of the Neurotensin Receptor NTR1

P. Kitabgi, J. Mazella, J. Bernassau, 1998, The Journal of Biological Chemistry.

Distribution of neurotensin binding sites in rat brain: A light microscopic radioautographic study using monoiodo [125I]Tyr3-neurotensin

A. Beaudet, E. Moyse, W. Rostène, 1987, Neuroscience.

Identification and functional characterization of a stable, centrally active derivative of the neurotensin (8-13) fragment as a potential first-in-class analgesic.

F. Hughes, T. Dix, Justin O. Brower, 2010, Journal of medicinal chemistry.

In vivo and in vitro structure-activity studies with peptide and pseudopeptide neurotensin analogs suggest the existence of distinct central neurotensin receptor subtypes.

A. Brouard, J. Costentin, W. Rostène, 1994, The Journal of pharmacology and experimental therapeutics.

Role of TREK-1 in Health and Disease, Focus on the Central Nervous System

C. Heurteaux, J. Mazella, M. Borsotto, 2019, Front. Pharmacol..

Spadin as a new antidepressant: Absence of TREK-1-related side effects

C. Heurteaux, C. Gandin, J. Mazella, 2012, Neuropharmacology.

Localization of the Somatostatin Receptor SST2A in Rat Brain Using a Specific Anti-Peptide Antibody

A. Beaudet, P. Dournaud, G. Tannenbaum, 1996, The Journal of Neuroscience.

Preferential Expression of sst2A over sst2B Somatostatin Receptor Splice Variant in Rat Brain and Pituitary

A. Beaudet, P. Sarret, J. Vincent, 1998, Neuroendocrinology.

Fluoxetine Protection in Decompression Sickness in Mice is Enhanced by Blocking TREK-1 Potassium Channel with the “spadin” Antidepressant

K. Lambrechts, J. Blatteau, J. Risso, 2016, Front. Physiol..

Neurotensin receptor 1

J. Vincent, J. Mazella, 2006 .

Regional and cellular distribution of low affinity neurotensin receptor mRNA in adult and developing mouse brain

A. Beaudet, P. Sarret, J. Vincent, 1998, The Journal of comparative neurology.

Identification in the rat neurotensin receptor of amino-acid residues critical for the binding of neurotensin.

A. Beaudet, P. Séguéla, J. Vincent, 1997, Brain research. Molecular brain research.

Identification and characterization of two zebrafish Twik related potassium channels, Kcnk2a and Kcnk2b

C. Jopling, C. Heurteaux, A. Faucherre, 2018, Scientific Reports.

Shortened Spadin Analogs Display Better TREK-1 Inhibition, In Vivo Stability and Antidepressant Activity

C. Heurteaux, J. Mazella, M. Borsotto, 2017, Front. Pharmacol..

Therapeutic potential of prenylated stilbenoid macasiamenene F through its anti-inflammatory and cytoprotective effects on LPS-challenged monocytes and microglia.

J. Hošek, J. Václavík, K. Šmejkal, 2020, Journal of ethnopharmacology.

First evidence of protective effects on stroke recovery and post-stroke depression induced by sortilin-derived peptides

C. Heurteaux, J. Mazella, M. Borsotto, 2019, Neuropharmacology.

Astroglial Control of the Antidepressant-Like Effects of Prefrontal Cortex Deep Brain Stimulation

Claude Gronfier, G. Wegener, P. Blier, 2015, EBioMedicine.

Sortilin derived propeptide regulation during adipocyte differentiation and inflammation.

T. Coppola, J. Mazella, Céline Hivelin, 2017, Biochemical and biophysical research communications.

Cellular and Sub-Cellular Localization of Brain Neurotensin Receptors

A. Beaudet, E. Moyse, J. Kessler, 1988 .

Retroinverso analogs of spadin display increased antidepressant effects

C. Heurteaux, G. Gaudriault, H. Moha ou Maati, 2014, Psychopharmacology.

Neurotensin receptors in GtoPdb v.2023.1

P. Sarret, J. Vincent, J. Mazella, 2023, IUPHAR/BPS Guide to Pharmacology CITE.

Targeting two‐pore domain K+ channels TREK‐1 and TASK‐3 for the treatment of depression: a new therapeutic concept

C. Heurteaux, M Borsotto, J Veyssiere, 2015, British journal of pharmacology.

Serum sortilin-derived propeptides concentrations are decreased in major depressive disorder patients.

M. Bortolomasi, A. Minelli, M. Gennarelli, 2017, Journal of affective disorders.

Identification and expression of a variant isoform of the levocabastine‐sensitive neurotensin receptor in the mouse central nervous system

P. Sarret, J. Vincent, J. Mazella, 1997, FEBS letters.

In vitro and in vivo regulation of synaptogenesis by the novel antidepressant spadin

C. Heurteaux, H. Moha ou Maati, J. Mazella, 2015, British journal of pharmacology.

Increased serum levels of sortilin-derived propeptide after electroconvulsive therapy in treatment-resistant depressed patients

M. Bortolomasi, A. Minelli, M. Gennarelli, 2018, Neuropsychiatric disease and treatment.

Effects of SR 48692 on neurotensin-induced calcium-activated chloride currents in the Xenopus oocyte expression system: agonist-like activity on the levocabastine-sensitive neurotensin receptor and absence of antagonist effect on the levocabastine insensitive neurotensin receptor

E. Guillemare, J. Vincent, J. Mazella, 1997, Neuroscience Letters.