Rajendra Tangallapally

发表

Discovery of an L-alanine ester prodrug of the Hsp90 inhibitor, MPC-3100.

V. Baichwal, J. Patton, A. Bajji, 2015, Bioorganic & medicinal chemistry letters.

Synthesis, optimization and structure-activity relationships of 3,5-disubstituted isoxazolines as new anti-tuberculosis agents.

Dianqing Sun, Richard E. Lee, Rakesh, 2009, European journal of medicinal chemistry.

Discovery of novel bacterial elongation condensing enzyme inhibitors by virtual screening.

C. Rock, Weixing Zhang, Richard E. Lee, 2014, Bioorganic & medicinal chemistry letters.

In Vivo and In Vitro Effects of a ClpP-Activating Antibiotic against Vancomycin-Resistant Enterococci

Richard E. Lee, Michael D. LaFleur, E. Griffith, 2018, Antimicrobial Agents and Chemotherapy.

Nitrofurans as novel anti-tuberculosis agents: identification, development and evaluation.

Richard E. Lee, Robin E. B. Lee, Antawan Daniels, 2007, Current topics in medicinal chemistry.

Synthesis and evaluation of cyclic secondary amine substituted phenyl and benzyl nitrofuranyl amides as novel antituberculosis agents.

A. Lenaerts, Richard E. Lee, Robin E. B. Lee, 2005, Journal of medicinal chemistry.

Synthesis and evaluation of nitrofuranylamides as novel antituberculosis agents.

K. Hevener, S. Franzblau, A. Lenaerts, 2004, Journal of medicinal chemistry.

Relief of CoA sequestration and restoration of mitochondrial function in a mouse model of propionic acidemia

C. Rock, C. Subramanian, S. White, 2022, Journal of inherited metabolic disease.

Pantothenate kinase activation relieves coenzyme A sequestration and improves mitochondrial function in mice with propionic acidemia

C. Rock, C. Subramanian, S. White, 2021, Science Translational Medicine.

Metabolic activation of CaMKII by coenzyme A.

Robert A. Harris, D. Green, Taosheng Chen, 2013, Molecular cell.

Discovery of (2S)-1-[4-(2-{6-amino-8-[(6-bromo-1,3-benzodioxol-5-yl)sulfanyl]-9H-purin-9-yl}ethyl)piperidin-1-yl]-2-hydroxypropan-1-one (MPC-3100), a purine-based Hsp90 inhibitor.

V. Baichwal, D. Cimbora, A. Bajji, 2012, Journal of medicinal chemistry.

Pharmacokinetically-Guided Lead Optimization of Nitrofuranylamide Anti-Tuberculosis Agents

B. Meibohm, N. Mehrotra, Richard E. Lee, 2008, The AAPS Journal.

Discovery of novel isoxazolines as anti-tuberculosis agents.

B. Meibohm, A. Lenaerts, Dianqing Sun, 2007, Bioorganic & medicinal chemistry letters.

Synthesis of new and potent analogues of anti-tuberculosis agent 5-nitro-furan-2-carboxylic acid 4-(4-benzyl-piperazin-1-yl)-benzylamide with improved bioavailability.

A. Lenaerts, Richard E. Lee, Robin E. B. Lee, 2006, Bioorganic & medicinal chemistry letters.

LipE guided discovery of isopropylphenyl pyridazines as pantothenate kinase modulators

C. Rock, C. Subramanian, S. White, 2021, Bioorganic & medicinal chemistry.

Ureadepsipeptides as ClpP Activators.

K. Lewis, B. Conlon, W. Shadrick, 2019, ACS infectious diseases.

Synthesis, optimization and structure-activity relationships of 3,5-disubstituted isoxazolines as new anti-tuberculosis agents.

Dianqing Sun, Richard E. Lee, Rakesh, 2009, European journal of medicinal chemistry.