K. Yager

发表

Discovery of an L-alanine ester prodrug of the Hsp90 inhibitor, MPC-3100.

V. Baichwal, J. Patton, A. Bajji, 2015, Bioorganic & medicinal chemistry letters.

Structure-based design, synthesis, and study of pyrazolo[1,5-a][1,3,5]triazine derivatives as potent inhibitors of protein kinase CK2.

C. Perretta, S. Margosiak, R. Almassy, 2007, Bioorganic & medicinal chemistry letters.

Investigations of an Antibody Ligase

S. Benkovic, Carol M. Taylor, J. Witherington, 1997 .

Libraries of N-alkylaminoheterocycles from nucleophilic aromatic substitution with purification by solid supported liquid extraction

Birong Zhang, Charles R. Johnson, K. Yager, 1998 .

Peptide synthesis catalyzed by an antibody containing a binding site for variable amino acids.

S. Benkovic, Carol M. Taylor, R. Hirschmann, 1994, Science.

Structure-based design, synthesis, and antimicrobial activity of indazole-derived SAH/MTA nucleosidase inhibitors.

K. Appelt, V. Feher, Xiaoming Li, 2003, Journal of medicinal chemistry.

Enantioselective Synthesis of Diverse .alpha.-Amino Phosphonate Diesters

Carol M. Taylor, Amos B. Smith, K. Yager, 1995 .

Asymmetric Synthesis of .alpha.-Aminophosphonates via Diastereoselective Addition of Lithium Diethyl Phosphite to Chelating Imines

Carol M. Taylor, Amos B. Smith, K. Yager, 1994 .

Delocalized Carbanions in Synthesis

N. Mills, T. Siahaan, C. Ogle, 1992 .

Asymmetric Synthesis of α-Aminophosphonates via Diastereoselective Addition of Lithium Diethyl Phosphite to Chelating Imines.

Carol M. Taylor, Amos B. Smith, K. Yager, 1995 .

Phosphonate Diester and Phosphonamide Synthesis. Reaction Coordinate Analysis by 31P NMR Spectroscopy: Identification of Pyrophosphonate Anhydrides and Highly Reactive Phosphonylammonium Salts1

Carol M. Taylor, J. Witherington, R. Hirschmann, 1997 .

Preparation and Reactions of Trianions from the Dimethylphenols

T. Siahaan, R. Bates, K. Yager, 1987 .

Asymmetric Synthesis of Diethyl (R)‐(−)‐(1‐Amino‐3‐Methylbutyl)Phosphonate

Carol M. Taylor, Amos B. Smith, K. Yager, 2003 .

Synthetic Studies of the Pyrroloquinoline Nucleus of the Makaluvamine Alkaloids. Synthesis of the Topoisomerase II Inhibitor Makaluvamine D

James D White, T. Yakura, K. Yager, 1994 .

Structure-based design, synthesis, and antimicrobial activity of purine derived SAH/MTA nucleosidase inhibitors.

K. Appelt, V. Feher, S. Margosiak, 2004, Bioorganic & medicinal chemistry letters.

Synthesis of dihydropallescensin D via manganese(III) mediated cyclization of an olefinic β-keto ester

James D White, T. Somers, K. Yager, 1990 .

Synthesis and conformation of 2-[[3-(1-hydroxyhexyl)phenoxy]methyl]quinoline, a 5-lipoxygenase inhibitor and leukotriene antagonist

James D White, F. Stappenbeck, K. Yager, 1993 .

Enantioselective Synthesis of Diverse α‐Amino Phosphonate Diesters.

Carol M. Taylor, Amos B. Smith, K. Yager, 1996 .

PHOSPHONYLTRIETHYLAMMONIUM SALTS : NOVEL REACTIVE SPECIES FOR THE SYNTHESIS OF PHOSPHONATE ESTERS AND PHOSPHONONAMIDES

Carol M. Taylor, J. Witherington, R. Hirschmann, 1995 .

Triterpene based compounds with potent anti-maturation activity against HIV-1.

Mark B. Anderson, V. Baichwal, J. Garrus, 2008, Bioorganic & medicinal chemistry letters.

Structure-based design, synthesis, and antimicrobial activity of purine derived SAH/MTA nucleosidase inhibitors.

K. Appelt, V. Feher, S. Margosiak, 2004, Bioorganic & medicinal chemistry letters.

Lead optimization of purine based orally bioavailable Mps1 (TTK) inhibitors.

P. Slattum, M. Bursavich, Bruce L. Roth, 2012, Bioorganic & medicinal chemistry letters.

Discovery of (2S)-1-[4-(2-{6-amino-8-[(6-bromo-1,3-benzodioxol-5-yl)sulfanyl]-9H-purin-9-yl}ethyl)piperidin-1-yl]-2-hydroxypropan-1-one (MPC-3100), a purine-based Hsp90 inhibitor.

V. Baichwal, D. Cimbora, A. Bajji, 2012, Journal of medicinal chemistry.

Novel Mps1 kinase inhibitors: from purine to pyrrolopyrimidine and quinazoline leads.

D. V. Kumar, M. Bursavich, D. Cimbora, 2013, Bioorganic & medicinal chemistry letters.

Cost-Utility of a Prognostic Test Guiding Adjuvant Chemotherapy Decisions in Early-Stage Non-Small Cell Lung Cancer.

U. Siebert, D. Brixner, R. Kaldate, 2016, The oncologist.

Structure-based design, synthesis, and study of potent inhibitors of β-ketoacyl-acyl carrier protein synthase III as potential antimicrobial agents

K. Gajiwala, K. Appelt, C. Perretta, 2005 .

Synthesis of diverse tetrahydro-β-carboline-3-carboxamides and -2,3-bis-lactams on a versatile 4-hydroxythiophenol-linked solid support

K. Yager, P. Fantauzzi, 1998 .

Libraries of N-alkylaminoheterocycles from nucleophilic aromatic substitution with purification by solid supported liquid extraction

Birong Zhang, Charles R. Johnson, K. Yager, 1998 .

Cell cycle progression score is a marker for five-year lung cancer-specific mortality risk in patients with resected stage I lung adenocarcinoma

David R. Jones, W. Travis, J. Chaft, 2016, Oncotarget.

Abstract B137: Pharmacokinetics, antitumor activity, and therapeutic index of Nampt inhibitor MPC-8640 in mice.

V. Baichwal, J. Boniface, R. Carlson, 2011 .

Lead optimization of purine based orally bioavailable Mps1 (TTK) inhibitors.

P. Slattum, M. Bursavich, Bruce L. Roth, 2012, Bioorganic & medicinal chemistry letters.