A. Gilliam

发表

Synthesis of long-chain amide analogs of the cannabinoid CB1 receptor antagonist N-(piperidinyl)-5-(4-chlorophenyl)-1-(2,4-dichlorophenyl)-4-methyl-1H-pyrazole-3-carboxamide (SR141716) with unique binding selectivities and pharmacological activities.

James B. Thomas, S. Fix, B. Thomas, 2005, Bioorganic & medicinal chemistry.

Synthesis and Biological Evaluation of Bivalent Ligands for the CB1 Receptor

M. Damaj, B. Thomas, R. Maitra, 2011 .

Synthesis and pharmacological comparison of dimethylheptyl and pentyl analogs of anandamide.

B. Thomas, R. Pertwee, D. R. Compton, 1997, Journal of medicinal chemistry.

The bioactive conformation of aminoalkylindoles at the cannabinoid CB1 and CB2 receptors: insights gained from (E)- and (Z)-naphthylidene indenes.

B. Thomas, R. Pertwee, B F Thomas, 1998, Journal of medicinal chemistry.

Conformationally constrained analogues of N-(piperidinyl)-5-(4-chlorophenyl)-1-(2,4- dichlorophenyl)-4-methyl-1H-pyrazole-3-carboxamide (SR141716): design, synthesis, computational analysis, and biological evaluations.

S. Mascarella, B. Thomas, M. Brackeen, 2008, Journal of medicinal chemistry.

Peripherally Selective Cannabinoid 1 Receptor (CB1R) Agonists for the Treatment of Neuropathic Pain.

I. Spigelman, R. Snyder, B. Thomas, 2016, Journal of medicinal chemistry.

Comparative receptor binding analyses of cannabinoid agonists and antagonists.

B. Thomas, B F Thomas, A F Gilliam, 1998, The Journal of pharmacology and experimental therapeutics.

Kappa opioid mediation of cannabinoid effects of the potent hallucinogen, salvinorin A, in rodents

J. Warner, H. Navarro, F. Carroll, 2010, Psychopharmacology.

The importance of hydrogen bonding and aromatic stacking to the affinity and efficacy of cannabinoid receptor CB2 antagonist, 5-(4-chloro-3-methylphenyl)-1-[(4-methylphenyl)methyl]-N-[(1S,2S,4R)-1,3,3-trimethylbicyclo[2.2.1]hept-2-yl]-1H-pyrazole-3-carboxamide (SR144528).

Evangelia Kotsikorou, Herbert H Seltzman, Dow P Hurst, 2013, Journal of medicinal chemistry.

Synthesis and Structure−Activity Relationships of Amide and Hydrazide Analogues of the Cannabinoid CB1 Receptor Antagonist N-(Piperidinyl)- 5-(4-chlorophenyl)-1-(2,4-dichlorophenyl)-4-methyl-1H-pyrazole-3-carboxamide (SR141716)

Herbert H Seltzman, B. Thomas, R. Pertwee, 2002 .

Synthesis and biological evaluation of bivalent ligands for the cannabinoid 1 receptor.

M. Damaj, B. Thomas, R. Maitra, 2010, Journal of medicinal chemistry.

Structure elucidation of a novel ring‐constrained biaryl pyrazole CB1 cannabinoid receptor antagonist

C. George, B. Thomas, H. Seltzman, 2003 .

Peripherally Selective Cannabinoid 1 Receptor (CB1R) Agonists for the Treatment of Neuropathic Pain.

I. Spigelman, R. Snyder, B. Thomas, 2016, Journal of medicinal chemistry.

Synthetic peripherally-restricted cannabinoid suppresses chemotherapy-induced peripheral neuropathy pain symptoms by CB1 receptor activation.

E. Hirt, H. Seltzman, A. Gilliam, 2016 .