S. Salowe

发表

A peptide-based fluorescence resonance energy transfer assay for Bacillus anthracis lethal factor protease

E. Scolnick, J. Hermes, R. Cummings, 2002, Proceedings of the National Academy of Sciences of the United States of America.

Anthrax lethal factor inhibition

E. Scolnick, A. Woods, D. Zaller, 2005, Proceedings of the National Academy of Sciences of the United States of America.

Oxidative cyclization chemistry catalyzed by clavaminate synthase

C. Townsend, A. Basak, S. Salowe, 1989 .

Stereochemical course of the key ring-forming reactions in clavulanic acid biosynthesis

C. Townsend, A. Basak, S. Salowe, 1990 .

Kibdelomycin A, a congener of kibdelomycin, derivatives and their antibacterial activities.

Scott K. Smith, J. Phillips, Jesús Martín, 2012, Bioorganic & medicinal chemistry letters.

Purification and Molecular Characterization of cGMP-dependent Protein Kinase from Apicomplexan Parasites

Jeffrey Yuan, D. Schmatz, B. Nare, 2002, The Journal of Biological Chemistry.

Regulation of calcineurin phosphatase activity and interaction with the FK-506.FK-506 binding protein complex.

R. Kincaid, S. O'keefe, G. Wiederrecht, 1994, The Journal of biological chemistry.

From Screening to Targeted Degradation: Strategies for the Discovery and Optimization of Small Molecule Ligands for PCSK9.

Sujata Sharma, J. Lisnock, P. Orth, 2019, Cell chemical biology.

Series of Novel and Highly Potent Cyclic Peptide PCSK9 Inhibitors Derived from an mRNA Display Screen and Optimized via Structure-Based Design.

K. Seyb, D. Johns, P. Orth, 2020, Journal of medicinal chemistry.

1,3,8-Triazaspiro[4.5]decane-2,4-diones as efficacious pan-inhibitors of hypoxia-inducible factor prolyl hydroxylase 1-3 (HIF PHD1-3) for the treatment of anemia.

J. Demartino, E. Sherer, P. Váchal, 2012, Journal of medicinal chemistry.

In Vitro Assays for the Discovery of PCSK9 Autoprocessing Inhibitors

J. Gesell, Shirly Pinto, M. Kavana, 2016, Journal of biomolecular screening.

The discovery of a potent and selective lethal factor inhibitor for adjunct therapy of anthrax infection.

E. Scolnick, A. Woods, D. Zaller, 2006, Bioorganic & Medicinal Chemistry Letters.

An ENDOR study of the tyrosyl free radical in ribonucleotide reductase from Escherichia coli

T. K. Chandrashekar, M. Sahlin, J. Stubbe, 1989 .

A MEDICINAL CHEMISTRY EVALUATION OF THE AUTOINHIBITORY DOMAIN OF CALCINEURIN

R. Tolman, A. B. Jones, S. Salowe, 1995 .

EXAFS Evidence for a "Cysteine Switch" in the Activation of Prostromelysin

Catherine K. Smith, R. Holz, L. Que, 1992 .

PAP inhibitor with in vivo efficacy identified by Candida albicans genetic profiling of natural products.

Yang Li, Li Zhang, Guy Harris, 2008, Chemistry & biology.

Disubstituted pyrimidines as Lck inhibitors.

A. Woods, D. Zaller, J. Hermes, 2009, Bioorganic & Medicinal Chemistry Letters.

Exafs studies of binuclear iron proteins hemerythrin and ribonucleotide reductase

L. Que, J. Stubbe, A. Roe, 1987 .

The NMR structure of the inhibited catalytic domain of human stromelysin–1

J. Springer, J. Hermes, P. Gooley, 1994, Nature Structural Biology.

Discovery of N-[Bis(4-methoxyphenyl)methyl]-4-hydroxy-2-(pyridazin-3-yl)pyrimidine-5-carboxamide (MK-8617), an Orally Active Pan-Inhibitor of Hypoxia-Inducible Factor Prolyl Hydroxylase 1-3 (HIF PHD1-3) for the Treatment of Anemia.

Jeffrey T. Kuethe, J. Demartino, E. Sherer, 2016, Journal of medicinal chemistry.

Elucidation of the order of oxidations and identification of an intermediate in the multistep clavaminate synthase reaction.

C. Townsend, S. Salowe, W. J. Krol, 1991, Biochemistry.

Characterization of zinc-binding sites in human stromelysin-1: stoichiometry of the catalytic domain and identification of a cysteine ligand in the proenzyme.

J. Hermes, Catherine K. Smith, C. K. Smith, 1992, Biochemistry.

Cloning, overproduction, and purification of the B2 subunit of ribonucleoside-diphosphate reductase

J. Stubbe, S. Salowe, 1986, Journal of bacteriology.

Purification and characterization of clavaminate synthase from Streptomyces clavuligerus: an unusual oxidative enzyme in natural product biosynthesis.

C. Townsend, E. Marsh, S. Salowe, 1990, Biochemistry.

Products of the inactivation of ribonucleoside diphosphate reductase from Escherichia coli with 2'-azido-2'-deoxyuridine 5'-diphosphate.

J. Stubbe, S P Salowe, M A Ator, 1987, Biochemistry.

Discovery of kibdelomycin, a potent new class of bacterial type II topoisomerase inhibitor by chemical-genetic profiling in Staphylococcus aureus.

Scott K. Smith, J. Phillips, Jesús Martín, 2011, Chemistry & biology.

Alternative model for mechanism-based inhibition of Escherichia coli ribonucleotide reductase by 2'-azido-2'-deoxyuridine 5'-diphosphate.

J. Bollinger, J. Stubbe, J. Peisach, 1993, Biochemistry.

Toxoplasma gondii Cyclic GMP-Dependent Kinase: Chemotherapeutic Targeting of an Essential Parasite Protein Kinase

B. Nare, Suresh B. Singh, P. Liberator, 2002, Eukaryotic Cell.

Competitive and slow-binding inhibition of calcineurin by drug x immunophilin complexes.

J. Hermes, S. Salowe, 1998, Archives of biochemistry and biophysics.

Antibacterial small molecules targeting the conserved TOPRIM domain of DNA gyrase

T. Roemer, Xinwei Sher, G. Scapin, 2017, PloS one.

EXAFS Studies of the B2 Subunit of the Ribonucleotide Reductase from E. coli

L. Que, J. Stubbe, M. Maroney, 1986 .

EXAFS Studies of the B2 Subunit of the Ribonucleotide Reductase from E. coli.

L. Que, J. Stubbe, M. Maroney, 1987 .

A Series of Novel, Highly Potent, and Orally Bioavailable Next-Generation Tricyclic Peptide PCSK9 Inhibitors.

Jeffrey T. Kuethe, D. Johns, P. Orth, 2021, Journal of medicinal chemistry.

The role of a parasite-specific allosteric site in the distinctive activation behavior of Eimeria tenella cGMP-dependent protein kinase.

P. Liberator, R. Donald, J. Wiltsie, 2002, Biochemistry.

The Catalytic Flexibility of tRNAIle-lysidine Synthetase Can Generate Alternative tRNA Substrates for Isoleucyl-tRNA Synthetase

J. Wiltsie, S. Salowe, L. Sonatore, 2009, Journal of Biological Chemistry.

2'-Azido-2'-deoxynucleotide interaction with E. coli ribonucleotide reductase: generation of a new radical species

JoAnne Stubbe, Morris J. Robins, J. Stubbe, 1984 .

From Screening to Targeted Degradation: Strategies for the Discovery and Optimization of Small Molecule Ligands for PCSK9.

Sujata Sharma, P. Orth, J. Shipman, 2021, Cell chemical biology.

1,3,8-Triazaspiro[4.5]decane-2,4-diones as efficacious pan-inhibitors of hypoxia-inducible factor prolyl hydroxylase 1-3 (HIF PHD1-3) for the treatment of anemia.

E. Sherer, K. Chapman, M. Wyvratt, 2012, Journal of medicinal chemistry.