Iram Khan

发表

Generation of a cost-effective cell line for support of high-throughput isolation of primary human B cells and monoclonal neutralizing antibodies

Aaron M. Seese, Abigail Wall, A. McGuire, 2020, Journal of Immunological Methods.

Normal collagen and bone production by gene-targeted human osteogenesis imperfecta iPSCs.

Pei-Rong Wang, D. Russell, D. Deyle, 2012, Molecular therapy : the journal of the American Society of Gene Therapy.

Engineering of human pluripotent stem cells by AAV-mediated gene targeting.

Angelique M. Nelson, C. Ware, Pei-Rong Wang, 2010, Molecular therapy : the journal of the American Society of Gene Therapy.

Progressive engineering of a homing endonuclease genome editing reagent for the murine X-linked immunodeficiency locus

Summer B. Thyme, D. Baker, A. Scharenberg, 2014, Nucleic acids research.

Pancreatic islet-specific engineered Tregs exhibit robust antigen-specific and bystander immune suppression in type 1 diabetes models

P. Linsley, D. Liggitt, D. Rawlings, 2022, Science Translational Medicine.

Ex vivo engineered human plasma cells exhibit robust protein secretion and long-term engraftment in vivo

D. Rawlings, N. Camp, R. James, 2022, Nature Communications.

Chapter 14 Nanocarriers as potential and effective delivery tool for COVID-19 drugs

Iram Khan, Sheikh Mansoor, Suhaib Shamas, 2022, Coronavirus Drug Discovery.

Safe and Effective Gene Therapy for Murine Wiskott-Aldrich Syndrome Using an Insulated Lentiviral Vector

D. Liggitt, A. Nienhuis, D. Rawlings, 2016, Molecular therapy. Methods & clinical development.

Intraosseous delivery of lentiviral vectors targeting factor VIII expression in platelets corrects murine hemophilia A.

D. Rawlings, C. Miao, D. Pan, 2015, Molecular therapy : the journal of the American Society of Gene Therapy.

Effective, safe, and sustained correction of murine XLA using a UCOE-BTK promoter-based lentiviral vector

B. Ryu, D. Rawlings, Joseph Pangallo, 2021, Molecular therapy. Methods & clinical development.

Lack of Genotoxicity due to Foamy Virus Vector Integration in Human iPSCs

D. Russell, D. Deyle, Iram Khan, 2013, Gene Therapy.

Successful treatment of canine leukocyte adhesion deficiency by foamy virus vectors

James M. Allen, D. Russell, David W Russell, 2008, Nature Medicine.

Gene editing to induce FOXP3 expression in human CD4+ T cells leads to a stable regulatory phenotype and function

T. Torgerson, A. Scharenberg, D. Rawlings, 2020, Science Translational Medicine.

Efficient modification of CCR5 in primary human hematopoietic cells using a megaTAL nuclease and AAV donor template

A. Scharenberg, D. Rawlings, Jordan Jarjour, 2015, Science Translational Medicine.

Rapamycin relieves lentiviral vector transduction resistance in human and mouse hematopoietic stem cells.

B. Torbett, D. Rawlings, H. Kiem, 2014, Blood.

Novel fluorescent genome editing reporters for monitoring DNA repair pathway utilization at endonuclease-induced breaks

Michelle Brault, David J. Rawlings, Michael T. Certo, 2013, Nucleic acids research.

Targeted gene editing restores regulated CD40L function in X-linked hyper-IgM syndrome.

H. Ochs, T. Torgerson, A. Scharenberg, 2016, Blood.

Engineering Protein-Secreting Plasma Cells by Homology-Directed Repair in Primary Human B Cells

D. Rawlings, I. Meitlis, R. James, 2017, Molecular therapy : the journal of the American Society of Gene Therapy.

AAV-mediated gene targeting methods for human cells

D. Russell, Iram Khan, R. Hirata, 2011, Nature Protocols.

High Efficiency CRISPR/Cas9-mediated Gene Editing in Primary Human T-cells Using Mutant Adenoviral E4orf6/E1b55k "Helper" Proteins.

Kyle Jacoby, Nicholas A. Popp, David J Rawlings, 2016, Molecular therapy : the journal of the American Society of Gene Therapy.

A lentiviral vector B cell gene therapy platform for the delivery of the anti-HIV-1 eCD4-Ig-knob-in-hole-reversed immunoadhesin

B. Torbett, D. Rawlings, R. James, 2023, Molecular therapy. Methods & clinical development.

Comparative expression profile of developmental related genes in haploid and diploid parthenogenetic embryos in caprine

Kuldeep Kumar, Renu Singh, R. Ranjan, 2013 .

132. Targeting the BTK Locus in Primary Human Hematopoietic Cells with TALENs and AAV Donor Template

D. Rawlings, Iram Khan, King L. Hung, 2016 .

Targeted gene editing restores regulated CD40L function in X-linked hyper-IgM syndrome.

H. Ochs, T. Torgerson, A. Scharenberg, 2016, Blood.

Intraosseous delivery of lentiviral vectors targeting factor VIII expression in platelets corrects murine hemophilia A.

D. Rawlings, C. Miao, D. Pan, 2015, Molecular therapy : the journal of the American Society of Gene Therapy.

DNA-PK inhibition enhances gene editing efficiency in HSPCs for CRISPR-based treatment of X-linked hyper IgM syndrome

Iram Khan, Mason P. Berger, Cole M. Pugliano, 2024, Molecular Therapy - Methods & Clinical Development.

Efficient and sustained FOXP3 locus editing in hematopoietic stem cells as a therapeutic approach for IPEX syndrome

Iram Khan, Yuchi Honaker, Swati Singh, 2023, Molecular therapy. Methods & clinical development.