N. Oleinik

发表

TGF-β receptor I/II trafficking and signaling at primary cilia are inhibited by ceramide to attenuate cell migration and tumor metastasis

P. Howe, C. Senkal, B. Ogretmen, 2017, Science Signaling.

Targeting FLT3-ITD signaling mediates ceramide-dependent mitophagy and attenuates drug resistance in AML.

M. Andreeff, S. Kornblau, B. Ogretmen, 2016, Blood.

Binding of the sphingolipid S1P to hTERT stabilizes telomerase at the nuclear periphery by allosterically mimicking protein phosphorylation

E. Skordalakes, Y. Peterson, E. Garrett-Mayer, 2015, Science Signaling.

Cooperation between JNK1 and JNK2 in activation of p53 apoptotic pathway

S. Krupenko, N. Krupenko, N. Oleinik, 2007, Oncogene.

Activation of p21-Dependent G1/G2 Arrest in the Absence of DNA Damage as an Antiapoptotic Response to Metabolic Stress.

S. Krupenko, N. Krupenko, N. Oleinik, 2011, Genes & cancer.

A Novel Tumor Suppressor Function of Glycine N-Methyltransferase Is Independent of Its Catalytic Activity but Requires Nuclear Localization

S. Krupenko, N. Krupenko, S. Ghose, 2013, PloS one.

Crystal structures reveal catalytic and regulatory mechanisms of the dual-specificity ubiquitin/FAT10 E1 enzyme Uba6

S. Olsen, E. Wasmuth, B. Ogretmen, 2022, Nature Communications.

Receptor-interacting Ser/Thr kinase 1 (RIPK1) and myosin IIA–dependent ceramidosomes form membrane pores that mediate blebbing and necroptosis

Y. Peterson, B. Ogretmen, R. Stahelin, 2018, The Journal of Biological Chemistry.

Mitochondrial protein import is regulated by p17/PERMIT to mediate lipid metabolism and cellular stress

Roger H. Johnson, B. Ogretmen, J. Lemasters, 2019, Science Advances.

Crosstalk between pro-survival sphingolipid metabolism and complement signaling induces inflammasome-mediated tumor metastasis

Y. Peterson, S. Mehrotra, B. Ogretmen, 2022, Cell reports.

ALDH1L2 Is the Mitochondrial Homolog of 10-Formyltetrahydrofolate Dehydrogenase*

S. Krupenko, K. Strickland, N. Krupenko, 2010, The Journal of Biological Chemistry.

10-formyltetrahydrofolate dehydrogenase, one of the major folate enzymes, is down-regulated in tumor tissues and possesses suppressor effects on cancer cells.

S. Krupenko, N. Oleinik, 2002, Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research.

ALDH1L1 Inhibits Cell Motility Via Dephosphorylation of Cofilin by PP1 and PP2A

S. Krupenko, N. Krupenko, N. Oleinik, 2010, Oncogene.

10-Formyltetrahydrofolate Dehydrogenase–Induced c-Jun-NH2-Kinase Pathways Diverge at the c-Jun-NH2-Kinase Substrate Level in Cells with Different p53 Status

S. Krupenko, N. Krupenko, S. Ghose, 2009, Molecular Cancer Research.

Epigenetic Silencing of ALDH1L1, a Metabolic Regulator of Cellular Proliferation, in Cancers.

S. Krupenko, N. Krupenko, N. Oleinik, 2011, Genes & cancer.

HPV/E7 induces chemotherapy‐mediated tumor suppression by ceramide‐dependent mitophagy

B. Ogretmen, Jisun Kim, Z. Szulc, 2017, EMBO molecular medicine.

Cancer cells activate p53 in response to 10-formyltetrahydrofolate dehydrogenase expression.

D. Priest, S. Krupenko, N. Krupenko, 2005, The Biochemical journal.

Rho GTPases RhoA and Rac1 Mediate Effects of Dietary Folate on Metastatic Potential of A549 Cancer Cells through the Control of Cofilin Phosphorylation*

K. Helke, S. Krupenko, N. Krupenko, 2014, The Journal of Biological Chemistry.

Cofilin Phosphorylation Potential of A 549 Cancer Cells through the Effects of Dietary Folate on Metastatic Rho GTPases RhoA and Rac 1 Mediate Molecular Bases of Disease :

K. Helke, S. Krupenko, N. Krupenko, 2014 .

Ectopic expression of 10-formyltetrahydrofolate dehydrogenase in A549 cells induces G1 cell cycle arrest and apoptosis.

S. Krupenko, N. Oleinik, 2003, Molecular cancer research : MCR.

Targeting glutamine-addiction and overcoming CDK4/6 inhibitor resistance in human esophageal squamous cell carcinoma

A. Bass, Kwok-Kin Wong, A. Rustgi, 2019, Nature Communications.

Depletion of COPI in cancer cells: the role of reactive oxygen species in the induction of lipid accumulation, noncanonical lipophagy and apoptosis

B. Ogretmen, M. Shtutman, G. Piroli, 2022, Molecular biology of the cell.

Mechanisms of Ceramide-Dependent Cancer Cell Death.

B. Ogretmen, N. Oleinik, Rose Nganga, 2018, Advances in cancer research.

JNK1/2 regulate Bid by direct phosphorylation at Thr59 in response to ALDH1L1

Y. Peterson, S. Krupenko, N. Krupenko, 2014, Cell Death and Disease.

Phylogeny and evolution of aldehyde dehydrogenase-homologous folate enzymes.

S. Krupenko, K. Strickland, N. Krupenko, 2011, Chemico-biological interactions.

Targeting glutamine-addiction and overcoming CDK4/6 inhibitor resistance in human esophageal squamous cell carcinoma

A. Bass, Kwok-Kin Wong, A. Rustgi, 2019, Nature Communications.

Leucovorin-induced resistance against FDH growth suppressor effects occurs through DHFR up-regulation.

S. Krupenko, N. Krupenko, Steven N. Reuland, 2006, Biochemical pharmacology.

Determining fracture toughness of materials by reference to their mechanical properties

N. Oleinik, Kuet Ngo, 1976 .

Acyl Carrier Protein-specific 4′-Phosphopantetheinyl Transferase Activates 10-Formyltetrahydrofolate Dehydrogenase*

S. Krupenko, K. Strickland, N. Krupenko, 2009, The Journal of Biological Chemistry.

Alterations of lipid‐mediated mitophagy result in aging‐dependent sensorimotor defects

B. Ogretmen, J. Kurtz, Z. Szulc, 2023, Aging Cell.

Binding of the sphingolipid S1P to hTERT stabilizes telomerase at the nuclear periphery by allosterically mimicking protein phosphorylation

E. Skordalakes, Y. Peterson, E. Garrett-Mayer, 2015, Science Signaling.