T. Orita

发表

Structure-based drug design of novel and highly potent pyruvate dehydrogenase kinase inhibitors.

H. Ueno, Tatsuo Akaki, T. Adachi, 2021, Bioorganic & medicinal chemistry.

Fragment-based lead discovery to identify novel inhibitors that target the ATP binding site of pyruvate dehydrogenase kinases.

I. Nakanishi, Tatsuo Akaki, T. Iwanaga, 2021, Bioorganic & medicinal chemistry.

Histone Deacetylase Inhibitor Activates the p21/WAF1/Cip1 Gene Promoter through the Sp1 Sites

T. Sakai, H. Nomura, K. Nakano, 1999, Annals of the New York Academy of Sciences.

Molecular Cloning, Genomic Structure, and Expression Analysis of MUC20, a Novel Mucin Protein, Up-regulated in Injured Kidney*

Hong-Wei Sun, D. Alcorta, Motonao Nakamura, 2004, Journal of Biological Chemistry.

Discovery of a Janus Kinase Inhibitor Bearing a Highly Three-Dimensional Spiro Scaffold: JTE-052 (Delgocitinib) as a New Dermatological Agent to Treat Inflammatory Skin Disorders.

Hiroshi Yamamoto, S. Noji, Hiromasa Hashimoto, 2020, Journal of medicinal chemistry.

Sp3, but not Sp1, mediates the transcriptional activation of the p21/WAF1/Cip1 gene promoter by histone deacetylase inhibitor.

T. Sakai, H. Nomura, Y. Sowa, 1999, Cancer research.

MUC20 Suppresses the Hepatocyte Growth Factor-Induced Grb2-Ras Pathway by Binding to a Multifunctional Docking Site of Met

Motonao Nakamura, Tadashi Yamamoto, Yutaka Saito, 2004, Molecular and Cellular Biology.

Inhibition of natural killer (NK) cell prevents graft-vs-host-disease after small bowel transplantation in rats.

K. Orita, T. Orita, M. Fujioka, 1992, Transplantation proceedings.

Histone deacetylase inhibitor activates the WAF1/Cip1 gene promoter through the Sp1 sites.

T. Sakai, H. Nomura, K. Nakano, 1997, Biochemical and biophysical research communications.

Identification by differential display of eight known genes induced during in vivo intimal hyperplasia

Yusuke Nakamura, Toshihiro Tanaka, H. Tomoike, 1998, Journal of Human Genetics.

Fragment-Based Discovery of Novel VE-PTP Inhibitors Using Orthogonal Biophysical Techniques.

Tatsuo Akaki, T. Adachi, K. Yamanaka, 2023, Biochemistry.

Design and synthesis of novel and potent allosteric HIV-1 integrase inhibitors with a spirocyclic moiety.

T. Orita, Y. Ohata, Susumu Miyazaki, 2024, Bioorganic & medicinal chemistry letters.