R. Rosa

发表

The use of stable-isotopically labeled oleic acid to interrogate lipid assembly in vivo: assessing pharmacological effects in preclinical species

D. Johns, Shirly Pinto, R. DeVita, 2011, Journal of Lipid Research.

Quantifying apoprotein synthesis in rodents: coupling LC-MS/MS analyses with the administration of labeled water

Michael E. Lassman, Kenny K. Wong, D. Johns, 2012, Journal of Lipid Research.

2-(4-carbonylphenyl)benzoxazole inhibitors of CETP: scaffold design and advancement in HDLc-raising efficacy.

S. Wright, S. Eveland, S. A. Hyland, 2011, Bioorganic & medicinal chemistry letters.

Simvastatin Has Anti-Inflammatory and Antiatherosclerotic Activities Independent of Plasma Cholesterol Lowering

Y. Chao, S. Wright, P. Detmers, 2000, Arteriosclerosis, thrombosis, and vascular biology.

Small molecule activation of lecithin cholesterol acyltransferase modulates lipoprotein metabolism in mice and hamsters.

N. Geoghagen, D. Johns, Vinit Shah, 2012, Metabolism: clinical and experimental.

Different roles of liver X receptor alpha and beta in lipid metabolism: effects of an alpha-selective and a dual agonist in mice deficient in each subtype.

L. Mitnaul, S. Wright, J. Menke, 2006, Biochemical pharmacology.

Biphenyl-substituted oxazolidinones as cholesteryl ester transfer protein inhibitors: modifications of the oxazolidinone ring leading to the discovery of anacetrapib.

Amjad Ali, S. Wright, Hong Li, 2011, Journal of medicinal chemistry.

Identification and validation of genes affecting aortic lesions in mice.

Joshua L. Deignan, E. Schadt, Jun Zhu, 2010, The Journal of clinical investigation.

Plasma lipid profiling across species for the identification of optimal animal models of human dyslipidemia[S]

N. Geoghagen, L. Mitnaul, Peggy H. Wong, 2012, Journal of Lipid Research.

Type 1 diabetes genes and pathways shared by humans and NOD mice.

Kara Hunter, John A Todd, J. Todd, 2005, Journal of autoimmunity.

Interleukin-2 gene variation impairs regulatory T cell function and causes autoimmunity

J. Rogers, J. Todd, S. Gregory, 2007, Nature Genetics.

Antibody‐mediated blockade of the CXCR3 chemokine receptor results in diminished recruitment of T helper 1 cells into sites of inflammation

J. Mudgett, J. Demartino, L. Wicker, 2003, Journal of leukocyte biology.

siRNA-induced liver ApoB knockdown lowers serum LDL-cholesterol in a mouse model with human-like serum lipids[S]

S. Bartz, Kenny K. Wong, L. Mitnaul, 2011, Journal of Lipid Research.

2-Arylbenzoxazoles as CETP inhibitors: raising HDL-C in cynoCETP transgenic mice.

Amjad Ali, S. Wright, Dooseop Kim, 2011, Bioorganic & medicinal chemistry letters.

Impact of drug distribution into adipose on tissue function: The cholesteryl ester transfer protein (CETP) inhibitor anacetrapib as a test case

D. Johns, Sheng-ping Wang, J. Hubert, 2019, Pharmacology research & perspectives.

2-(4-Carbonylphenyl)benzoxazole inhibitors of CETP: attenuation of hERG binding and improved HDLc-raising efficacy.

S. Eveland, S. A. Hyland, C. Sparrow, 2011, Bioorganic & medicinal chemistry letters.

An Anti-PCSK9 Antibody Reduces LDL-Cholesterol On Top Of A Statin And Suppresses Hepatocyte SREBP-Regulated Genes

N. Geoghagen, L. Mitnaul, D. Johns, 2012, International journal of biological sciences.

A PCSK9-binding antibody that structurally mimics the EGF(A) domain of LDL-receptor reduces LDL cholesterol in vivo1[S]

Lora Hamuro, Jayne Chin, L. Mitnaul, 2011, Journal of Lipid Research.

Different roles of liver X receptor α and β in lipid metabolism: Effects of an α-selective and a dual agonist in mice deficient in each subtype

Qiu Guo, Jayne Chin, L. Mitnaul, 2006 .

SAR studies: designing potent and selective LXR agonists.

Jayne Chin, L. Mitnaul, Shaei Huang, 2006, Bioorganic & medicinal chemistry letters.

Quantitative profiling of oxylipins in plasma and atherosclerotic plaques of hypercholesterolemic rabbits

T. Hankemeier, D. Johns, A. Harms, 2015, Analytical and Bioanalytical Chemistry.

Comparison of Lipoprotein Separation and Lipid Analysis Methodologies for Human and Cynomolgus Monkey Plasma Samples

N. Geoghagen, D. Johns, J. Castro-Pérez, 2012, Journal of Cardiovascular Translational Research.

Fine Mapping, Gene Content, Comparative Sequencing, and Expression Analyses Support Ctla4 and Nramp1 as Candidates for Idd5.1 and Idd5.2 in the Nonobese Diabetic Mouse 1

Luc J. Smink, Linda S. Wicker, John A. Todd, 2004, The Journal of Immunology.

Plasma lipid profiling across species for the identification of optimal animal models of human dyslipidemia[S]

N. Geoghagen, L. Mitnaul, Peggy H. Wong, 2012, Journal of Lipid Research.

Tracking fatty acid kinetics in distinct lipoprotein fractions in vivo: a novel high-throughput approach for studying dyslipidemia in rodent models

D. Johns, J. Castro-Pérez, T. Roddy, 2013, Journal of Lipid Research.