D. Irani

发表

David J. Miller, R. Keep, C. Dobry, 2014 .

Type-1 angiotensin receptor signaling in central nervous system myeloid cells is pathogenic during fatal alphavirus encephalitis in mice

A. Huber, P. Blakely, D. Irani, 2016, Journal of Neuroinflammation.

Manipulation of host factors optimizes the pathogenesis of western equine encephalitis virus infections in mice for antiviral drug development

David J. Miller, Phillip C. Delekta, P. Blakely, 2015, Journal of NeuroVirology.

Glutamate receptor antagonists protect from virus‐induced neural degeneration

J. Rothstein, D. Griffin, Jennifer L. Nargi-Aizenman, 2004, Annals of neurology.

Immune Responses to Non-Tumor Antigens in the Central Nervous System

A. Huber, D. Irani, P. Duncker, 2014, Front. Oncol..

THE NATURAL HISTORY OF RELAPSING AND PROGRESSIVE MS AND IMPLICATIONS FOR INTERRUPTING THE UNDERLYING DISEASE PROCESSES One of the major goals of the McDonald criteria

C. Markowitz, D. Irani, 2022 .

Dysregulation of the IL-23/IL-17 axis and myeloid factors in secondary progressive MS

S. Ekholm, A. Huber, A. Srinivasan, 2014, Neurology.

Diagnosis and prevention of bovine spongiform encephalopathy and variant Creutzfeldt-Jakob disease.

Richard T. Johnson, D. Irani, 2003, Annual review of medicine.

Central nervous system inflammation: can't live with it, can't live without it

D. Irani, 2001, Current opinion in neurology.

Regulation of t cell responses during central nervous system viral infection

D. Griffin, D. Irani, 2001, Advances in Virus Research.

Activation of Divergent Neuronal Cell Death Pathways in Different Target Cell Populations during Neuroadapted Sindbis Virus Infection of Mice

D. Griffin, B. Schofield, D. Irani, 2000, Journal of Virology.

Neuroprotective Interventions Targeting Detrimental Host Immune Responses Protect Mice From Fatal Alphavirus Encephalitis

N. Prow, D. Irani, 2007, Journal of neuropathology and experimental neurology.

West Nile virus encephalitis in the United States

Richard T. Johnson, D. Irani, 2002, Current neurology and neuroscience reports.

The neuropsychiatry of the transmissible spongiform encephalopathies (prion diseases)

D. Irani, 2001 .

Relapse in Guillain‐Barré syndrome after treatment with human immune globulin

D. Hanley, C. Borel, D. Cornblath, 1993, Neurology.

Regulation of brain-derived T cells during acute central nervous system inflammation.

D. Griffin, K. Lin, D. Irani, 1997, Journal of immunology.

The susceptibility of mice to immune-mediated neurologic disease correlates with the degree to which their lymphocytes resist the effects of brain-derived gangliosides.

D. Irani, 1998, Journal of immunology.

Brain-Derived Gangliosides Lymphocytes Resist the Effects of Correlates with the Degree to Which Their Immune-Mediated Neurologic Disease The Susceptibility of Mice to

D. Irani, 1998 .

The classic and variant forms of Creutzfeldt-Jakob disease.

D. Irani, 2003, Seminars in clinical neuropsychiatry.

The immune response in viral encephalitis.

D. Griffin, B. Levine, Beth Levine, 1992, Seminars in immunology.

Immune reconstitution inflammatory syndrome in the CNS of HIV-infected patients

D. Reich, P. Calabresi, P. Burger, 2006, Neurology.

Brain-derived gangliosides induce cell cycle arrest in a murine T cell line

D. Irani, 1998, Journal of Neuroimmunology.

Regulation of lymphocyte homing into the brain during viral encephalitis at various stages of infection.

D. Griffin, D. Irani, Diane E. Griffin, 1996, Journal of immunology.

How much control does the brain exert over the immune system?

D. Irani, 2002, Current opinion in neurology.

Interferon β in multiple sclerosis: is IL-12 suppression the key?

C. Karp, C. Biron, D. Irani, 2000 .

Interferon beta in multiple sclerosis: is IL-12 suppression the key?

C. Karp, C. Biron, D. Irani, 2000, Immunology today.

Proposed diagnostic criteria and nosology of acute transverse myelitis

L. Morrison, F. Pidcock, B. Lateur, 2003 .

Human Embryonic Germ Cell Derivatives Facilitate Motor Recovery of Rats with Diffuse Motor Neuron Injury

Jeffrey D. Rothstein, Nicholas J. Maragakis, Douglas A. Kerr, 2003, The Journal of Neuroscience.

Characteristics and Reversibility of Dementia in Normal Pressure Hydrocephalus

A. Hillis, C. Davis, D. Rigamonti, 2007, Behavioural neurology.

The inflammatory cytokine, interleukin‐1 beta, mediates loss of astroglial glutamate transport and drives excitotoxic motor neuron injury in the spinal cord during acute viral encephalomyelitis

N. Prow, David N Irani, Natalie A Prow, 2008, Journal of neurochemistry.

Optimization of novel indole-2-carboxamide inhibitors of neurotropic alphavirus replication.

David J. Miller, R. Keep, C. Dobry, 2013, Journal of medicinal chemistry.

Neurological Infections

D. Griffin, D. Irani, 1998, Encyclopedia of Immunology.

Discovery of Potent Broad Spectrum Antivirals Derived from Marine Actinobacteria

David J. Miller, D. Sherman, A. Tai, 2013, PloS one.

Immunological mechanisms in multiple sclerosis

D. Irani, 2005 .

Novel inhibitors of neurotropic alphavirus replication that improve host survival in a mouse model of acute viral encephalitis.

David J. Miller, R. Keep, S. Larsen, 2012, Journal of medicinal chemistry.

Manipulation of host factors optimizes the pathogenesis of western equine encephalitis virus infections in mice for antiviral drug development

David J. Miller, Phillip C. Delekta, P. Blakely, 2015, Journal of NeuroVirology.

Novel Indole-2-Carboxamide Compounds Are Potent Broad-Spectrum Antivirals Active against Western Equine Encephalitis Virus In Vivo

David J. Miller, R. Keep, C. Dobry, 2014, Journal of Virology.

Aseptic meningitis and viral myelitis.

D. Irani, 2008, Neurologic clinics.

Type-1 angiotensin receptor signaling in central nervous system myeloid cells is pathogenic during fatal alphavirus encephalitis in mice

A. Huber, P. Blakely, D. Irani, 2016, Journal of Neuroinflammation.

Virus-induced CD8+ T cells accelerate the onset of experimental autoimmune encephalomyelitis: Implications for how viral infections might trigger multiple sclerosis exacerbations

A. Huber, B. Segal, P. Blakely, 2013, Journal of Neuroimmunology.

Disrupted Glutamate Transporter Expression in the Spinal Cord With Acute Flaccid Paralysis Caused by West Nile Virus Infection

K. Tyler, B. Kleinschmidt-DeMasters, P. Blakely, 2009, Journal of neuropathology and experimental neurology.

The opioid receptor antagonist, naloxone, protects spinal motor neurons in a murine model of alphavirus encephalomyelitis

N. Prow, D. Irani, 2007, Experimental Neurology.

Viral-Induced Spinal Motor Neuron Death Is Non-Cell-Autonomous and Involves Glutamate Excitotoxicity

J. Rothstein, D. Kerr, Stephanie T Backovic, 2004, The Journal of Neuroscience.

BCL-2 and BAX Protect Adult Mice from Lethal Sindbis Virus Infection but Do Not Protect Spinal Cord Motor Neurons or Prevent Paralysis

Diane E. Griffin, D. Griffin, J. Hardwick, 2002, Journal of Virology.

Multiple sclerosis risk after optic neuritis: final optic neuritis treatment trial follow-up.

Melvin Greer, Neil R. Miller, Michael Wall, 2008, Archives of neurology.

14-3-3 protein in the cerebrospinal fluid of patients with acute transverse myelitis

D. Kerr, D. Irani, 2000, The Lancet.

Targeting CXCL13 During Neuroinflammation.

A. Huber, D. Irani, A. Huber, 2015, Advances in neuroimmune biology.

CHAPTER 34 – Future Directions in Cerebrospinal Fluid Analysis

D. Irani, 2009 .

Loss of the Ubiquitin-conjugating Enzyme UBE2W Results in Susceptibility to Early Postnatal Lethality and Defects in Skin, Immune, and Male Reproductive Systems*

H. Paulson, S. Schnell, K. Elenitoba-Johnson, 2015, The Journal of Biological Chemistry.

Isolation of brain parenchymal lymphocytes for flow cytometric analysis. Application to acute viral encephalitis.

D. Griffin, D. Irani, 1991, Journal of immunological methods.

Regulated Production of CXCL13 within the Central Nervous System

D. Irani, 2016, Journal of clinical & cellular immunology.

The lymphoid chemokine, CXCL13, is dispensable for the initial recruitment of B cells to the acutely inflamed central nervous system

N. Esen, B. Segal, J. Rumble, 2010, Brain, Behavior, and Immunity.

Approach to the Patient with Abnormal Cerebrospinal Fluid Protein Content

J. Blakeley, D. Irani, 2009 .

CHAPTER 18 – Nutritional and Metabolic Disorders

L. Turtzo, D. Irani, 2009 .

Complexity of the microglial activation pathways that drive innate host responses during lethal alphavirus encephalitis in mice

N. Esen, P. Blakely, D. Irani, 2012, ASN neuro.

Progressive multifocal leukoencephalopathy selectively affecting Broca's and Wernicke's areas in an immunocompetent patient: A case report

Renaid B. Kim, John Kim, D. Irani, 2023, Radiology case reports.

14-3-3 Protein in CSF: An Early Predictor of SIV CNS Disease

M. Zink, K. Helke, J. Mankowski, 2005, Journal of neuropathology and experimental neurology.

Cerebrospinal fluid levels of MMP‐2, 7, and 9 are elevated in association with human immunodeficiency virus dementia

K. Conant, D. Griffin, L. Wahl, 1999, Annals of neurology.

Type-I Interferons Suppress Microglial Production of the Lymphoid Chemokine, CXCL13

A. Huber, N. Esen, P. Blakely, 2014, Glia.

Inflammatory bowel disease patient concerns and experiences on transition to home-based infusions during the COVID-19 pandemic

A. Fendrick, P. Higgins, A. Waljee, 2022, Research in Social and Administrative Pharmacy.

An emerging role for eotaxins in neurodegenerative disease.

A. Huber, B. Segal, D. Irani, 2016, Clinical immunology.

Cleavage of cystatin C in the cerebrospinal fluid of patients with multiple sclerosis

Justin C McArthur, Caroline Anderson, Peter A Calabresi, 2006, Annals of neurology.

Brain MRI Findings of Hemophagocytic Lymphohistiocytosis With a Heterozygous PRF1 Gene Mutation Masquerading As CLIPPERS: A Case Report

T. Moritani, John Kim, A. Capizzano, 2023, Cureus.

The conundrum of interferon-β non-responsiveness in relapsing-remitting multiple sclerosis.

A. Huber, D. Irani, P. Duncker, 2015, Cytokine.

Cerebrospinal fluid protein carbonylation identifies oxidative damage in autoimmune demyelination

D. Irani, 2016, Annals of clinical and translational neurology.

Brain-derived gangliosides regulate the cytokine production and proliferation of activated T cells.

D. Griffin, K. Lin, D. Irani, 1996, Journal of immunology.

Engineered immunological niches to monitor disease activity and treatment efficacy in relapsing multiple sclerosis

R. Oakes, S. Miller, L. Shea, 2020, Nature Communications.

Astrocyte matricellular proteins that control excitatory synaptogenesis are regulated by inflammatory cytokines and correlate with paralysis severity during experimental autoimmune encephalomyelitis

P. Blakely, D. Irani, S. Hussain, 2015, Front. Neurosci..

MULTIPLE SCLEROSIS: THERAPEUTIC FRONTIERS AND PROGRESSIVE DISEASE *

C. Markowitz, D. Irani, 2008 .

CHAPTER 10 – Properties and Composition of Normal Cerebrospinal Fluid

D. Irani, 2009 .

Cerebrospinal Fluid in Clinical Practice

David N. Irani, D. Irani, 2008 .

Aseptic meningitis and viral myelitis.

D. Irani, 2008, Neurologic clinics.