L. Peterson

发表

Investigation of the Hsp90 C-terminal Binding Site, Novel Inhibitors and Isoform-Dependent Client Proteins

L. Peterson, 2012 .

C32-O-imidazol-2-yl-methyl ether derivatives of the immunosuppressant ascomycin with improved therapeutic potential.

F. Dumont, G. Wiederrecht, M. Wyvratt, 1998, Bioorganic & medicinal chemistry letters.

Analogs of cyclosporin A modified at the D-Ala8 position.

O. Hensens, F. Dumont, A. Patchett, 1992, The Journal of antibiotics.

The hERG channel is dependent upon the Hsp90α isoform for maturation and trafficking.

B. Blagg, G. Vielhauer, L. Peterson, 2012, Molecular pharmaceutics.

N. Sigal, S. O'keefe, M. Martin, 1998, Transplantation.

Potent immunosuppressive C32-O-arylethyl ether derivatives of ascomycin with reduced toxicity.

F. Dumont, G. Wiederrecht, M. Wyvratt, 1999, Bioorganic & medicinal chemistry letters.

C32-O-imidazol-2-yl-methyl ether derivatives of the immunosuppressant ascomycin with improved therapeutic potential.

F. Dumont, G. Wiederrecht, M. Wyvratt, 1998, Bioorganic & medicinal chemistry letters.

Osmomechanical stress selectively regulates translocation of protein kinase C isoforms

R. O'neil, X. Liu, L. Peterson, 2003, FEBS letters.

3-Arylcoumarin derivatives manifest anti-proliferative activity through Hsp90 inhibition.

B. Blagg, Huiping Zhao, L. Peterson, 2012, ACS medicinal chemistry letters.

Targeting the heat shock protein 90 dimer with dimeric inhibitors.

B. Blagg, J. Holzbeierlein, Huiping Zhao, 2011, Journal of medicinal chemistry.

Click chemistry to probe Hsp90: Synthesis and evaluation of a series of triazole-containing novobiocin analogues.

B. Blagg, L. Peterson, 2010, Bioorganic & medicinal chemistry letters.

Click Chemistry to Probe Hsp90: Synthesis and Evaluation of a Series of Triazole‐Containing Novobiocin Analogues.

B. Blagg, L. Peterson, 2010 .

Development of a Grp94 inhibitor.

C. Nicchitta, B. Blagg, D. Moore, 2012, Journal of the American Chemical Society.

Elucidation of the Hsp90 C-terminal inhibitor binding site.

Anshuman Dixit, Gennady M Verkhivker, Sudhakar Voruganti, 2011, ACS chemical biology.

Gambogic acid, a natural product inhibitor of Hsp90.

B. Blagg, R. Matts, B. Krumm, 2011, Journal of natural products.

To fold or not to fold: modulation and consequences of Hsp90 inhibition.

B. Blagg, L. Peterson, 2009, Future medicinal chemistry.

Synthesis and evaluation of novologues as C-terminal Hsp90 inhibitors with cytoprotective activity against sensory neuron glucotoxicity.

R. Dobrowsky, B. Blagg, Liangyu Zhang, 2012, Journal of medicinal chemistry.

Gedunin Inactivates the Co-chaperone p23 Protein Causing Cancer Cell Death by Apoptosis*♦

B. Blagg, A. Chadli, A. Fauq, 2013, The Journal of Biological Chemistry.

Selective Mitogen Activated Protein Kinase Activity Sensors through the Application of Directionally Programmable D Domain Motifs

M. Yaffe, B. Imperiali, L. Peterson, 2014, Biochemistry.

Is cyclophilin involved in the immunosuppressive and nephrotoxic mechanism of action of cyclosporin A?

N. Sigal, D. Rich, F. Dumont, 1991, The Journal of experimental medicine.

Synthesis and evaluation of electron-rich curcumin analogues.

B. Blagg, L. Peterson, M. Amolins, 2009, Bioorganic & medicinal chemistry.

Development of a Grp 94 inhibitor

C. Nicchitta, B. Blagg, D. Moore, 2012 .

1 Real-Time and Continuous Sensors of Protein Kinase Activity Utilizing Chelation-Enhanced Fluorescence

B. Imperiali, L. Peterson, 2014 .

Development of a Grp94 inhibitor.

C. Nicchitta, B. Blagg, D. Moore, 2012, Journal of the American Chemical Society.

The hERG channel is dependent upon the Hsp90α isoform for maturation and trafficking.

B. Blagg, G. Vielhauer, L. Peterson, 2012, Molecular pharmaceutics.