R. Testa

发表

Inhibitory activity of avibactam against selected β-lactamases expressed in an isogenic Escherichia coli strain.

V. di Pilato, G. Rossolini, T. Giani, 2016, Diagnostic microbiology and infectious disease.

Mannopeptimycins, New Cyclic Glycopeptide Antibiotics Produced by Streptomyces hygroscopicus LL-AC98: Antibacterial and Mechanistic Activities

P. Bradford, P. Petersen, E. Lenoy, 2003, Antimicrobial Agents and Chemotherapy.

Comparative in vitro and in vivo activities of piperacillin combined with the beta-lactamase inhibitors tazobactam, clavulanic acid, and sulbactam

N. Jacobus, P. Petersen, W. Weiss, 1989, Antimicrobial Agents and Chemotherapy.

Activities of ceftazidime, ceftaroline, and aztreonam alone and combined with avibactam against isogenic Escherichia coli strains expressing selected single β-lactamases.

R. Bonomo, M. Jacobs, S. Bajaksouzian, 2015, Diagnostic microbiology and infectious disease.

Glycylcyclines: a new generation of tetracyclines.

G. Ellestad, R. Testa, F. Tally, 1995, The Journal of antimicrobial chemotherapy.

Biochemical Characterization of Novel Tetrahydrofuranyl 1β-Methylcarbapenems: Stability to Hydrolysis by Renal Dehydropeptidases and Bacterial β-Lactamases, Binding to Penicillin Binding Proteins, and Permeability Properties

K. Bush, Youjun Yang, B. Rasmussen, 1999, Antimicrobial Agents and Chemotherapy.

Incorporation of L-methionine-methyl-14C into gentamicins.

C. Schaffner, G. Wagman, C. Liu, 1975, The Journal of antibiotics.

In Vitro Activities of Ceftazidime-Avibactam and Aztreonam-Avibactam against 372 Gram-Negative Bacilli Collected in 2011 and 2012 from 11 Teaching Hospitals in China

Qi Wang, Xiaojuan Wang, Hui Wang, 2013, Antimicrobial Agents and Chemotherapy.

Streptomyces stramineus sp. nov., a new species of the verticillate streptomycetes.

M. Lechevalier, D. Labeda, R. Testa, 1997, International journal of systematic bacteriology.

Glycomyces, a New Genus of the Actinomycetales

H. Lechevalier, M. Lechevalier, D. Labeda, 1985 .

Saccharothrix: a New Genus of the Actinomycetales Related to Nocardiopsis

H. Lechevalier, M. Lechevalier, D. Labeda, 1984 .

Verdamicin, a New Broad Spectrum Aminoglycoside Antibiotic

G. Wagman, J. Waitz, M. Weinstein, 1975, Antimicrobial Agents and Chemotherapy.

Antibiotic 6640, a new Micromonospora-produced aminoglycoside antibiotic.

G. Wagman, J. Waitz, M. Weinstein, 1970, The Journal of antibiotics.

Preliminary studies on megalomicin, a new Micromonospora-produced macrolide antibiotic complex.

G. Wagman, J. Waitz, M. Weinstein, 1968, Antimicrobial agents and chemotherapy.

Biotransformation, a new approach to aminoglycoside biosynthesis: II. Gentamicin.

R. Testa, B. C. Tilley, 1976, The Journal of antibiotics.

Biotransformation, a new approach to aminoglycoside biosynthesis. I. Sisomicin.

R. Testa, B. C. Tilley, 1975, The Journal of antibiotics.

Mutamicins; biosynthetically created new sisomicin analogues.

G. Wagman, M. Weinstein, R. Testa, 1974, The Journal of antibiotics.

Pyrido [3,4-e]-1,2,4-triazines and related heterocycles as potential antifungal agents.

M. Reich, P. Fabio, R. Testa, 1989, Annals of the New York Academy of Sciences.

In vitro and in vivo activities of LJC10,627, a new carbapenem with stability to dehydropeptidase I

N. Jacobus, P. Petersen, W. Weiss, 1991, Antimicrobial Agents and Chemotherapy.

Synthesis and structure-activity relationships of novel THF 1β-methylcarbapenems

S. Lang, K. Bush, S. Sakya, 1997 .

Synthesis and biological activity of derivatives of glycopeptide antibiotics eremomycin and vancomycin nitrosated, acylated or carbamoylated at the N-terminal.

M. Preobrazhenskaya, P. Petersen, R. Testa, 1993, The Journal of antibiotics.

In Vitro and In Vivo Antibacterial Activities of a Novel Glycylcycline, the 9-t-Butylglycylamido Derivative of Minocycline (GAR-936)

N. Jacobus, P. Petersen, W. Weiss, 1999, Antimicrobial Agents and Chemotherapy.

In vitro and in vivo antibacterial activities of the glycylcyclines, a new class of semisynthetic tetracyclines

N. Jacobus, F. Tally, P. Petersen, 1993, Antimicrobial Agents and Chemotherapy.

LL-AF283 antibiotics, cyclic biphenyl peptides.

M. Siegel, G. Morton, D. Borders, 1991, The Journal of antibiotics.

Calicheamicins, a novel family of antitumor antibiotics. 3. Isolation, purification and characterization of calicheamicins beta 1Br, gamma 1Br, alpha 2I, alpha 3I, beta 1I, gamma 1I and delta 1I.

D. Williams, D. Borders, D R Williams, 1989, The Journal of antibiotics.

New Polyene Antifungal Antibiotic Produced by a Species of Actinoplanes

G. Wagman, J. Waitz, M. Weinstein, 1975, Antimicrobial Agents and Chemotherapy.

In vitro and in vivo antibacterial effects of combinations of beta-lactam antibiotics

R. Testa, N. Kuck, N. Kuck, 1981, Antimicrobial Agents and Chemotherapy.

In Vitro Activities of Aminomethyl-Substituted Analogs of Novel Tetrahydrofuranyl Carbapenems

N. Jacobus, P. Petersen, Yang-i Lin, 1999, Antimicrobial Agents and Chemotherapy.

Synergistic activity of piperacillin: YTR-830H combinations in vitro and in vivo.

N. Jacobus, F. Tally, P. Petersen, 1989, Journal of chemotherapy.

In vitro and in vivo efficacy of YTR-830H and piperacillin combinations versus beta-lactamase-producing bacteria.

P. Petersen, W. Weiss, R. Testa, 1989, Journal of chemotherapy.

In Vitro Susceptibility of Characterized β-Lactamase-Producing Strains Tested with Avibactam Combinations

G. Jacoby, K. Bush, W. Nichols, 2014, Antimicrobial Agents and Chemotherapy.

"Glycylcyclines". 3. 9-Aminodoxycyclinecarboxamides.

P. Petersen, R. Testa, B. Buckwalter, 1994, Journal of medicinal chemistry.

Glycylcyclines. 1. A new generation of potent antibacterial agents through modification of 9-aminotetracyclines.

J. Bloom, Y. Gluzman, F. Tally, 1994, Journal of medicinal chemistry.

Synthesis and antibacterial activity of 9-substituted minocycline derivatives.

P. Petersen, R. Testa, P. Sum, 2006, Bioorganic & medicinal chemistry letters.

Susceptibility of enterococci, methicillin-resistant Staphylococcus aureus and Streptococcus pneumoniae to the glycylcyclines.

N. Jacobus, P. Petersen, W. Weiss, 1995, The Journal of antimicrobial chemotherapy.

Comparative efficacy of new investigational agents against Helicobacter pylori

M. Osato, A. Piergies, W. Bochenek, 2001, Alimentary pharmacology & therapeutics.

A new broad spectrum aminoglycoside antibiotic, G-52, produced by Micromonospora zionensis.

G. Wagman, J. Waitz, M. Weinstein, 1976, The Journal of antibiotics.

Antibiotic G-418, a New Micromonospora-Produced Aminoglycoside with Activity Against Protozoa and Helminths: Fermentation, Isolation, and Preliminary Characterization

G. Wagman, M. Weinstein, J. Marquez, 1974, Antimicrobial Agents and Chemotherapy.

Antibiotic 6640. II. Fermentation, isolation, and properties.

G. Wagman, J. Marquez, R. Testa, 1970, The Journal of antibiotics.

Chemical and Biological Modification of Antibiotics of the Gentamicin Group

R. Testa, J. J. Wright, T. L. Nagabhushan, 1980 .

A new Micromonospora-produced macrolide antibiotic, rosamicin.

G. Wagman, J. Waitz, M. Weinstein, 1972, The Journal of antibiotics.

Susceptibility of anaerobes in phase 3 clinical studies of piperacillin/tazobactam.

N. Jacobus, F. Immermann, R. Testa, 1993, Clinical infectious diseases : an official publication of the Infectious Diseases Society of America.

Physiology of Growth and Sporulation in Bacillus cereus I. Effect of Glutamic and Other Amino Acids

D. Lundgren, R. Testa, F. Buono, 1966, Journal of bacteriology.

In vitro susceptibility of characterized β-lactamase-producing Gram-negative bacteria isolated in Japan to ceftazidime-, ceftaroline-, and aztreonam-avibactam combinations.

K. Tateda, Y. Ishii, W. Nichols, 2015, Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy.

InVitro andInVivoActivities ofLJC10,627, a New Carbapenem withStability toDehydropeptidase I

P. J. Petersen, N. V. Jacobus, W. J. Weiss, 1991 .

Megalomicin, a new macrolide antibiotic complex produced by Micromonospora.

G. Wagman, J. Waitz, M. Weinstein, 1969, The Journal of antibiotics.

In vitro activity of ceftazidime, ceftaroline and aztreonam alone and in combination with avibactam against European Gram-negative and Gram-positive clinical isolates.

P. Nordmann, H. Seifert, G. Rossolini, 2015, International journal of antimicrobial agents.

In Vivo Activities of Peptidic Prodrugs of Novel Aminomethyl Tetrahydrofuranyl-1β-Methylcarbapenems

N. Jacobus, P. Petersen, Yang-i Lin, 1999, Antimicrobial Agents and Chemotherapy.

FERMENTATION, ISOLATION, AND PROPERTIES

R. Testa, Márquez, Joseph, 2006 .

Peptidic prodrugs of novel aminomethyl-THF 1β-methylcarbapenems

S. Lang, K. Bush, S. Sakya, 1997 .

Mono and bis double ester prodrugs of novel aminomethyl-THF 1β-methylcarbapenems

S. Lang, K. Bush, S. Sakya, 1997 .

Pyrido(3,4-e)-1,2,4-triazines and Related Heterocycles as Potential Antifungal Agents.

M. Reich, P. Fabio, R. Testa, 1989 .

New antitumor antibiotic, LL-D05139 beta. Fermentation, isolation, structure determination and biological activities.

D. Borders, R. Testa, M. Greenstein, 1987, The Journal of antibiotics.

FERMENTATION , ISOLATION , STRUCTURE DETERMINATION AND BIOLOGICAL ACTIVITIES

M. Lee, D. Borders, R. Testa, 2006 .

LL-F42248 alpha, a novel chlorinated pyrrole antibiotic.

G. Carter, T. S. Dunne, D. Borders, 1987, The Journal of antibiotics.

New antitumor antibiotic, LL-C10037 alpha. Fermentation, isolation and structure determination.

G. Morton, D. Borders, R. Testa, 1984, The Journal of antibiotics.

Sulfinemycin, a new anthelmintic antibiotic: fermentation, isolation and structure determination.

T. M. Lee, M. Siegel, G. Morton, 1995, The Journal of antibiotics.