J. Roland

发表

Discovery of short-course antiwolbachial quinazolines for elimination of filarial worm infections

Matthew S. Tremblay, H. M. Petrassi, K. Kuhen, 2019, Science Translational Medicine.

Discovery of a Small-Molecule Modulator of Glycosaminoglycan Sulfation.

Michelle S. Miller, L. Hsieh‐Wilson, Jian Liu, 2017, ACS chemical biology.

Nidufexor (LMB763), a Novel FXR Modulator for the Treatment of Nonalcoholic Steatohepatitis (NASH).

I. Sancho-Martinez, P. McNamara, S. Joseph, 2020, Journal of medicinal chemistry.

Cell-specific discrimination of desmosterol and desmosterol mimetics confers selective regulation of LXR and SREBP pathways in macrophages

Matthew S. Tremblay, C. Glass, N. Spann, 2017, bioRxiv.

A small molecule UPR modulator for diabetes identified by high throughput screening

Matthew S. Tremblay, S. Joseph, A. Chatterjee, 2021, Acta pharmaceutica Sinica. B.

Dissociated sterol‐based liver X receptor agonists as therapeutics for chronic inflammatory diseases

Matthew S. Tremblay, C. Glass, A. Chatterjee, 2016, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

A novel inhibitor of inducible NOS dimerization protects against cytokine‐induced rat beta cell dysfunction

Matthew S. Tremblay, P. Schultz, D. Eizirik, 2018, British journal of pharmacology.

Imaging of Plasmodium Liver Stages to Drive Next-Generation Antimalarial Drug Discovery

Yingyao Zhou, G. Bonamy, K. Kuhen, 2011, Science.

KAI407, a Potent Non-8-Aminoquinoline Compound That Kills Plasmodium cynomolgi Early Dormant Liver Stage Parasites In Vitro

K. Kuhen, E. Winzeler, A. Thomas, 2013, Antimicrobial Agents and Chemotherapy.

Targeting Plasmodium phosphatidylinositol 4-kinase to eliminate malaria

K. Kuhen, E. Winzeler, S. Meister, 2013, Nature.

Efficacy and Tolerability of Pyrazolo[1,5-a]pyrimidine RET Kinase Inhibitors for the Treatment of Lung Adenocarcinoma.

Nanxin Li, J. Shaffer, S. Kasibhatla, 2020, ACS medicinal chemistry letters.

Targeting Plasmodium PI(4)K to eliminate malaria

Robert W. Sauerwein, Bruce Russell, David C. Tully, 2013, Nature.

Cell-specific discrimination of desmosterol and desmosterol mimetics confers selective regulation of LXR and SREBP in macrophages

Matthew S. Tremblay, C. Glass, N. Spann, 2018, Proceedings of the National Academy of Sciences.

Lead optimization of imidazopyrazines: a new class of antimalarial with activity on Plasmodium liver stages.

Paul W Smith, K. Kuhen, E. Winzeler, 2014, ACS medicinal chemistry letters.

Antitarget Selectivity and Tolerability of Novel Pyrrolo[2,3-d]pyrimidine RET Inhibitors.

Nanxin Li, J. Shaffer, S. Kasibhatla, 2021, ACS medicinal chemistry letters.