R. Hedstrom

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Safety, tolerability and humoral immune responses after intramuscular administration of a malaria DNA vaccine to healthy adult volunteers.

J. Maguire, D. Doolan, P. Hobart, 2000, Vaccine.

Protection against malaria by immunization with plasmid DNA encoding circumsporozoite protein.

S. Hoffman, P. Hobart, M. Sedegah, 1994, Proceedings of the National Academy of Sciences of the United States of America.

DNA vaccination as an approach to malaria control: current status and strategies.

S. Hoffman, M. Gardner, H. Wang, 1998, Current topics in microbiology and immunology.

DNA vaccination against malaria

S. Hoffman, J. Aguiar, D. Doolan, 1996 .

Protection against malaria by immunization with a Plasmodium yoelii circumsporozoite protein nucleic acid vaccine.

S. Hoffman, M. Sedegah, R. Hedstrom, 1994, Vaccine.

Circumventing Genetic Restriction o f Protect ion against Malaria with Multigene D N A Immunizat ion : CD 8 + T Cell-, Interferon ~-, and Nitric

Stephen, D. Doolan, M. Sedegah, 2003 .

Circumventing genetic restriction of protection against malaria with multigene DNA immunization: CD8+ cell-, interferon gamma-, and nitric oxide-dependent immunity

S. Hoffman, D. Doolan, P. Hobart, 1996, The Journal of experimental medicine.

Cloning of the proteinase that facilitates infection by schistosome parasites.

P. Barr, J. McKerrow, N. Agabian, 1988, The Journal of biological chemistry.

Safety, tolerability, and lack of antibody responses after administration of a PfCSP DNA malaria vaccine via needle or needle-free jet injection, and comparison of intramuscular and combination intramuscular/intradermal routes.

S. Hoffman, E. Gorak, Sanjai Kumar, 2002, Human gene therapy.

Safety of a GM-CSF adjuvant-plasmid DNA malaria vaccine

S. Hoffman, S. Hoffman, H. Horton, 2001, Gene Therapy.

Effect on antibody and T-cell responses of mixing five GMP-produced DNA plasmids and administration with plasmid expressing GM-CSF

J. Sacci, J. Aguiar, M. Sedegah, 2004, Genes and Immunity.

In vitro expression and in vivo immunogenicity of Plasmodium falciparum pre-erythrocytic stage DNA vaccines.

S. Hoffman, M. Gardner, J. Sacci, 1998, International journal of molecular medicine.

Plasmid DNA malaria vaccine: tissue distribution and safety studies in mice and rabbits.

S. Hoffman, P. Hobart, S. Parker, 1999, Human gene therapy.

A plasmid encoding murine granulocyte-macrophage colony-stimulating factor increases protection conferred by a malaria DNA vaccine.

S. Hoffman, K. Ishii, K. Barnhart, 1998, Journal of immunology.

Simultaneous Induction of Multiple Antigen-Specific Cytotoxic T Lymphocytes in Nonhuman Primates by Immunization with a Mixture of Four Plasmodium falciparum DNA Plasmids

S. Hoffman, M. Gardner, J. Sacci, 1998, Infection and Immunity.

The development of a multivalent DNA vaccine for malaria

S. Hoffman, M. Gardner, J. Sacci, 2004, Springer Seminars in Immunopathology.

Toward clinical trials of DNA vaccines against malaria

S. Hoffman, D. Doolan, P. Hobart, 1997, Immunology and cell biology.

Ethylenediaminetetraacetate-extractable protein-lipopolysaccharide complex of Pseudomonas aeruginosa: characterization of protein components

R. G. Eagon, R. Hedstrom, R. K. Schockley, 1981, Journal of bacteriology.

Cloning of a gene involved in regulation of exotoxin A expression in Pseudomonas aeruginosa

D. Galloway, J. Kaper, C. Funk, 1986, Infection and immunity.

Improving Protective Immunity Induced by DNA-Based Immunization: Priming with Antigen and GM-CSF-Encoding Plasmid DNA and Boosting with Antigen-Expressing Recombinant Poxvirus1 2

S. Hoffman, J. Sacci, P. Hobart, 2000, The Journal of Immunology.

Recombinant Poxvirus DNA and Boosting with Antigen-Expressing Antigen and GM-CSF-Encoding Plasmid DNA-Based Immunization: Priming with Improving Protective Immunity Induced by

Stephen, J. Sacci, P. Hobart, 2000 .

Prospects and strategies for development of DNA vaccines against malaria.

S. Hoffman, M. Sedegah, R. Hedstrom, 1994, Research in immunology.

Nucleic Acid Malaria Vaccines

D. Doolan, P. Hobart, K. Gowda, 1995 .

Nucleic acid malaria vaccines. Current status and potential.

S. Hoffman, D. Doolan, P. Hobart, 1995, Annals of the New York Academy of Sciences.

Plasmid DNA malaria vaccine: the potential for genomic integration after intramuscular injection.

S. Hoffman, P. Hobart, S. Parker, 1999, Human gene therapy.

Antibody response of infected mice to outer membrane proteins of Pseudomonas aeruginosa

D. Galloway, O. Pavlovskis, R. Hedstrom, 1984, Infection and immunity.

Strategy for development of a pre-erythrocytic Plasmodium falciparum DNA vaccine for human use.

S. Hoffman, J. Aguiar, D. Doolan, 1997, Vaccine.

aeruginosa.to exotoxin A from Pseudomonas Production and characterization of monoclonal

D. Galloway, O. Pavlovskis, R. Hedstrom, 2013 .

Production and characterization of monoclonal antibodies to exotoxin A from Pseudomonas aeruginosa

D. Galloway, O. Pavlovskis, R. Hedstrom, 1984, Infection and immunity.

Production andCharacterization ofMonoclonal Antibodies to Exotoxin A fromPseudomonas aeruginosa

D. Galloway, R. Hedstrom, R. Pavlovskis, 1984 .

Induction of antigen-specific cytotoxic T lymphocytes in humans by a malaria DNA vaccine.

S. Hoffman, D. Doolan, P. Hobart, 1998, Science.

Induction of CD4+ T cell-dependent CD8+ type 1 responses in humans by a malaria DNA vaccine

S. Hoffman, D. Carucci, D. Doolan, 2001, Proceedings of the National Academy of Sciences of the United States of America.

Identification and Characterization of the Protective Hepatocyte Erythrocyte Protein 17 kDa Gene of Plasmodium yoelii, homolog of Plasmodium falciparum Exported Protein 1*

S. Hoffman, P. de la Vega, D. Doolan, 1996, The Journal of Biological Chemistry.

The immune response to stage-specific proteolytic enzymes of Schistosoma mansoni.

J. McKerrow, R. Hedstrom, A. MacInnis, 1987 .

Schistosome heat-shock proteins are immunologically distinct host-like antigens.

N. Agabian, G. Newport, J. Culpepper, 1988, Molecular and biochemical parasitology.

Clinical trial in healthy malaria-naïve adults to evaluate the safety, tolerability, immunogenicity and efficacy of MuStDO5, a five-gene, sporozoite/hepatic stage Plasmodium falciparum DNA vaccine combined with escalating dose human GM-CSF DNA

S. Hoffman, D. Freilich, J. Aguiar, 2012, Human vaccines & immunotherapeutics.

Identification, molecular cloning, and expression of a schistosome antigen displaying diagnostic potential.

P. Tarr, N. Agabian, G. Newport, 1988, The American journal of tropical medicine and hygiene.

DNA vaccines against malaria: immunogenicity and protection in a rodent model.

M. Gardner, J. Aguiar, H. Wang, 1996, Journal of pharmaceutical sciences.

Protection of Mice against Plasmodium yoelii Sporozoite Challenge with P. yoelii Merozoite Surface Protein 1 DNA Vaccines

S. Hoffman, M. Gardner, J. Aguiar, 1998, Infection and Immunity.

Boosting with recombinant vaccinia increases immunogenicity and protective efficacy of malaria DNA vaccine.

S. Hoffman, P. Hobart, J. Tine, 1998, Proceedings of the National Academy of Sciences of the United States of America.

Comparison of kinetics of active tetracycline uptake and active tetracycline efflux in sensitive and plasmid RP4-containing Pseudomonas putida

R. G. Eagon, R. Hedstrom, B. Crider, 1982, Journal of bacteriology.

Enhancement of the immune response in rabbits to a malaria DNA vaccine by immunization with a needle-free jet device.

S. Hoffman, S. Hoffman, J. Sacci, 2001, Vaccine.

Killer Whale Predation on Sea Otters Linking Oceanic and Nearshore Ecosystems

Denise L. Doolan, D. Doolan, P. Hobart, 1998 .

Characterization of the gene encoding sporozoite surface protein 2, a protective Plasmodium yoelii sporozoite antigen.

S. Hoffman, S. Hoffman, W. Rogers, 1992, Molecular and biochemical parasitology.

A DNA vaccine encoding the 42 kDa C-terminus of merozoite surface protein 1 of Plasmodium falciparum induces antibody, interferon-gamma and cytotoxic T cell responses in rhesus monkeys: immuno-stimulatory effects of granulocyte macrophage-colony stimulating factor.

S. Hoffman, J. Aguiar, D. Kaslow, 2002, Immunology letters.

A major immunogen in Schistosoma mansoni infections is homologous to the heat-shock protein Hsp70

R. Harrison, N. Agabian, G. Newport, 1987, The Journal of experimental medicine.

Biochemical analysis of CRM 66. A nonfunctional Pseudomonas aeruginosa exotoxin A.

D. Galloway, D. Wozniak, R. Hedstrom, 1989, The Journal of biological chemistry.

DNA vaccines for malaria: the past, the present, & the future.

S. Hoffman, D. Doolan, P. Hobart, 1997, The Indian journal of medical research.

A malaria sporozoite surface antigen distinct from the circumsporozoite protein.

S. Hoffman, J. Campbell, M. Sedegah, 1990, Bulletin of the World Health Organization.

Protection against malaria by immunization with plasmid DNA encoding circumsporozoite protein.

P. Hobart, M. Sedegah, R. Hedstrom, 1994, Proceedings of the National Academy of Sciences of the United States of America.