K. Thia

发表

Neonatal Cytomegalovirus Palatal Ulceration and Bocavirus Pneumonitis Associated With a Defect of Lymphocyte Cytotoxicity Caused by Mutations in UNC13D.

I. Voskoboinik, P. Palasanthiran, R. Mitchell, 2019, Journal of the Pediatric Infectious Diseases Society.

Late-Onset Non-HLH Presentations of Growth Arrest, Inflammatory Arachnoiditis, and Severe Infectious Mononucleosis, in Siblings with Hypomorphic Defects in UNC13D

J. Trapani, I. Voskoboinik, I. Andrews, 2017, Front. Immunol..

Heterozygosity for the common perforin mutation, p.A91V, impairs the cytotoxicity of primary natural killer cells from healthy individuals

R. Tothill, J. Trapani, A. Brennan, 2015, Immunology and cell biology.

Perforin is a major contributor to NK cell control of tumor metastasis.

M. Smyth, E. Cretney, A. Scalzo, 1999, Journal of immunology.

A clathrin/dynamin- and mannose-6-phosphate receptor–independent pathway for granzyme B–induced cell death

J. Trapani, D. Jans, M. Sandrin, 2003, The Journal of cell biology.

Cloning and characterization of a novel NK cell-specific serine protease gene and its functional 5′-flanking sequences

J. Trapani, T. Sayers, H. Young, 2004, Immunogenetics.

Functional dissociation of ΔΨm and cytochrome c release defines the contribution of mitochondria upstream of caspase activation during granzyme B-induced apoptosis

D. Green, J. Trapani, R. Johnstone, 2006, Cell Death and Differentiation.

HYPOTHESIS: CYTOTOXIC LYMPHOCYTE GRANULE SERINE PROTEASES ACTIVATE TARGET CELL ENDONUCLEASES TO TRIGGER APOPTOSIS

J. Trapani, M. Smyth, M. Kershaw, 1994, Clinical and experimental pharmacology & physiology.

Blockade of the co-inhibitory molecule PD-1 unleashes ILC2-dependent anti-tumor immunity in melanoma

Melissa J. Davis, S. Hediyeh-zadeh, W. Shi, 2021, Nature Immunology.

Perforin is a major contributor to NK cell control of tumor metastasis.

M. Smyth, E. Cretney, A. Scalzo, 1999, Journal of immunology.

Human perforin mutations and susceptibility to multiple primary cancers

J. Trapani, C. Gedye, I. Campbell, 2013, Oncoimmunology.

Expression of recombinant human Met-ase-1: a NK cell-specific granzyme.

J. Trapani, M. Smyth, J. M. Kelly, 1995, Biochemical and biophysical research communications.

Granzyme B Encoded by the Commonly Occurring Human RAH Allele Retains Pro-apoptotic Activity*

J. Trapani, P. Bird, Jiuru Sun, 2004, Journal of Biological Chemistry.

The natural killer cell serine protease gene Lmet1 maps to mouse chromosome 10

N. Copeland, D. Gilbert, N. Jenkins, 2004, Immunogenetics.

The granzyme B gene is highly polymorphic in wild mice but essentially invariant in common inbred laboratory strains.

J. Trapani, K. Thia, 2007, Tissue antigens.

Xenogeneic mouse anti‐human NK cytotoxicity is mediated via perforin

M. Smyth, M. Kershaw, K. Thia, 1997 .

This information is current as Granzyme B Activated Mouse B Cells Lack Expression of Hawkins and

J. Trapani, G. Belz, D. Tarlinton, 2012 .

Expression of recombinant human granzyme B. A processing and activation role for dipeptidyl peptidase I.

M. Smyth, K. Thia, M. Mcguire, 1995, Journal of immunology.

Adaptive reprogramming of NK cells in X-linked lymphoproliferative syndrome.

J. Trapani, S. Opat, I. Voskoboinik, 2018, Blood.

Familial haemophagocytic lymphohistiocytosis: Australian experience and perspectives

J. Trapani, I. Voskoboinik, K. Thia, 2014, Internal medicine journal.

Perforin-Mediated Cytotoxicity Is Critical for Surveillance of Spontaneous Lymphoma

J. Trapani, M. Smyth, D. Godfrey, 2000, The Journal of experimental medicine.

Differential Tumor Surveillance by Natural Killer (Nk) and Nkt Cells

J. Trapani, M. Smyth, E. Cretney, 2000, The Journal of experimental medicine.

Antigen-driven EGR2 expression is required for exhausted CD8+ T cell stability and maintenance

Timothy J. Peters, J. Trapani, F. Luciani, 2021, Nature Communications.

Characterization of the treatment-naive immune microenvironment in melanoma with BRAF mutation

Melissa J. Davis, S. Zadeh, J. Trapani, 2022, Journal for ImmunoTherapy of Cancer.

Fatal immune dysregulation due to a gain of glycosylation mutation in lymphocyte perforin.

J. Trapani, A. Brennan, I. Voskoboinik, 2012, Blood.

Differential effects of BTK inhibitors ibrutinib and zanubrutinib on NK-cell effector function in patients with mantle cell lymphoma

J. Trapani, Xiaomin Song, A. Roberts, 2020, Haematologica.

Bi-Allelic Mutations in STXBP2 Reveal a Complementary Role for STXBP1 in Cytotoxic Lymphocyte Killing

N. Brown, J. Trapani, I. Voskoboinik, 2018, Front. Immunol..

lymphocyte perforin Fatal immune dysregulation due to a gain of glycosylation mutation in

J. Trapani, A. Brennan, I. Voskoboinik, 2013 .

Cloning and expression of the recombinant mouse natural killer cell granzymeMet-ase-1

M. Smyth, M. Hulett, J. M. Kelly, 2007, Immunogenetics.

Serglycin determines secretory granule repertoire and regulates natural killer cell and cytotoxic T lymphocyte cytotoxicity

J. Trapani, A. Brennan, R. Johnstone, 2016, The FEBS journal.

Cloning and expression of the recombinant mouse natural killer cell granzyme Met-ase-1.

M. Smyth, M. Hulett, J. M. Kelly, 1996, Immunogenetics.

TSTEM-like CAR-T cells exhibit improved persistence and tumor control compared with conventional CAR-T cells in preclinical models

J. Desai, J. Trapani, P. Ekert, 2023, Science Translational Medicine.

A Natural Genetic Variant of Granzyme B Confers Lethality to a Common Viral Infection

J. Trapani, G. Karupiah, P. Bird, 2014, PLoS pathogens.

A clathrin/dynamin- and mannose-6-phosphate receptor–independent pathway for granzyme B–induced cell death

J. Trapani, D. Jans, M. Sandrin, 2003, The Journal of cell biology.

Differential Tumor Surveillance by Natural Killer (Nk) and Nkt Cells

J. Trapani, M. Smyth, E. Cretney, 2000, The Journal of experimental medicine.

Recovery of natural killer cell cytotoxicity in a A91V perforinhomozygous patient following severe haemophagocytic lymphohistiocytosis

J. McNeil, J. Trapani, I. Kerridge, 2020, British journal of haematology.