Z. Fleischmann

发表

A mitochondria-specific mutational signature of aging: increased rate of A>G substitutions on a heavy chain

A. Reymond, V. Makeev, K. Khrapko, 2022, bioRxiv.

Mitochondrial mutational spectrum in mammals is sensitive to cellular and organismal longevity by means of A>G transitions

A. Reymond, S. Nikolaev, J. Fellay, 2020 .

A mitochondrial mutational signature of temperature in ectothermic and endothermic vertebrates

J. Fellay, K. Khrapko, W. Kunz, 2020, bioRxiv.

Mitochondrial mutational spectrum provides an universal marker of cellular and organismal longevity

A. Reymond, S. Nikolaev, K. Khrapko, 2019 .

Mitochondrial Pseudogenes Suggest Repeated Inter-Species Hybridization among Direct Human Ancestors

L. Peshkin, K. Khrapko, K. Popadin, 2017, bioRxiv.

Nuclear DNA-encoded fragments of mitochondrial DNA (mtDNA) confound analysis of selection of mtDNA mutations in human primordial germ cells

K. Khrapko, J. Tilly, D. Woods, 2021, bioRxiv.

A mitochondria-specific mutational signature of aging: increased rate of A > G substitutions on the heavy strand

A. Reymond, V. Makeev, J. Fellay, 2022, Nucleic acids research.

Direction mutation pressure of SARS-CoV-2 helps to understand the past and predict the future evolution: C>U and G>U biased mutagenesis forces the majority of amino-acid substitutions to be from CG-rich losers to U-rich gainers

J. Fellay, K. Khrapko, K. Popadin, 2022, bioRxiv.

LUCS: a high-resolution nucleic acid sequencing tool for accurate long-read analysis of individual DNA molecules

K. Khrapko, J. Tilly, D. Woods, 2020, Aging.

Direction mutation pressure of SARS-CoV-2 helps to understand the past and predict the future evolution: C>U and G>U biased mutagenesis forces the majority of amino-acid substitutions to be from CG-rich losers to U-rich gainers

J. Fellay, K. Khrapko, K. Popadin, 2022, bioRxiv.

Dynamics of the most common pathogenic mtDNA variant m.3243A>G demonstrate frequency-dependency in blood and positive selection in the germline

D. Turnbull, K. Khrapko, M. Braverman, 2022, bioRxiv.

Bi-phasic dynamics of the mitochondrial DNA mutation m.3243A>G in blood: An unbiased, mutation level-dependent model implies positive selection in the germline

D. Turnbull, K. Khrapko, M. Braverman, 2021 .

3GOLD: optimized Levenshtein distance for clustering third-generation sequencing data

K. Khrapko, J. Tilly, D. Woods, 2021, BMC Bioinform..

Friend or Foe: Can Mitochondrial Toxins Lead to Similar Benefits as Exercise?

K. Khrapko, J. Tilly, D. Woods, 2018 .

Mitochondrial mutational spectrum is associated with mammalian longevity: a novel signature of oxidative damage

A. Reymond, V. Makeev, J. Fellay, 2021 .

Workflow Optimization for Identification of Female Germline or Oogonial Stem Cells in Human Ovarian Cortex Using Single-Cell RNA Sequence Analysis

J. Tilly, D. Woods, O. Ishihara, 2022, Stem cells.

Mammalian mitochondrial mutational spectrum as a hallmark of cellular and organismal aging

A. Reymond, S. Nikolaev, J. Fellay, 2019, bioRxiv.

Reanalysis of mtDNA mutations of human primordial germ cells (PGCs) reveals NUMT contamination and suggests that selection in PGCs may be positive

K. Khrapko, J. Tilly, D. Woods, 2023, bioRxiv.

Quasi-Mendelian Paternal Inheritance of mitochondrial DNA: A notorious artifact, or anticipated mtDNA behavior?

K. Khrapko, D. Woods, W. Kunz, 2019, bioRxiv.

Quasi-Mendelian paternal inheritance of mitochondrial DNA: A notorious artifact, or anticipated behavior?

K. Khrapko, D. Woods, W. Kunz, 2019, Proceedings of the National Academy of Sciences.

A mitochondrial mutational signature of temperature and longevity in ectothermic and endothermic vertebrates

J. Fellay, K. Khrapko, W. Kunz, 2020 .