I. Tosi

发表

Quantitative 3T MR imaging of the descending thoracic aorta: patients with familial hypercholesterolemia have an increased aortic plaque burden despite long-term lipid-lowering therapy.

S. Schmitz, D. O’Regan, J. Hajnal, 2008, Journal of vascular and interventional radiology : JVIR.

Characterization of innate lymphoid cells (ILC) in human skin and blood demonstrates increase of NKp44+ ILC3 in psoriasis

F. Villanova, F. Nestle, P. Di Meglio, 2013, The Journal of investigative dermatology.

MRI at 3 Tesla detects no evidence for ischemic brain damage in intensively treated patients with homozygous familial hypercholesterolemia

S. Schmitz, D. O’Regan, J. Hajnal, 2007, Neuroradiology.

Downregulation of Fas gene expression in Sézary syndrome is associated with promoter hypermethylation.

S. Whittaker, T. Mitchell, Chung-Ching Chu, 2010, The Journal of investigative dermatology.

LYMPHOID NEOPLASIA Candidate driver genes involved in genome maintenance and DNA repair in S´ezary syndrome

M. Simpson, S. Whittaker, Charlotte E. Flanagan, 2016 .

CYP1A1 Enzymatic Activity Influences Skin Inflammation Via Regulation of the AHR Pathway

B. Stockinger, F. Nestle, P. Di Meglio, 2020, The Journal of investigative dermatology.

Coronavirus disease 2019 subphenotypes and differential treatment response to convalescent plasma in critically ill adults: secondary analyses of a randomized clinical trial

J. Williams, M. Shankar-Hari, P. Klenerman, 2022, Intensive Care Medicine.

Targeting CD8(+) T cells prevents psoriasis development.

F. Villanova, F. Nestle, P. Di Meglio, 2016, The Journal of allergy and clinical immunology.

Regulation of T-plastin expression by promoter hypomethylation in primary cutaneous T-cell lymphoma.

S. Whittaker, M. Bagot, T. Mitchell, 2012, The Journal of investigative dermatology.

Infantile systemic hyalinosis associated with a putative splice‐site mutation in the ANTXR2 gene

J. McGrath, D. Chirla, I. Tosi, 2012, Clinical and experimental dermatology.

Enhanced NF-κB signaling in type-2 dendritic cells at baseline predicts non-response to adalimumab in psoriasis

M. Barnes, F. Nestle, P. Di Meglio, 2021, Nature communications.

Enhanced NF-κB signaling in type-2 dendritic cells at baseline predicts non-response to adalimumab in psoriasis

R. Emsley, M. Barnes, K. Payne, 2020, Nature Communications.

Evaluation of Immunophenotypic and Molecular Biomarkers for Sézary Syndrome Using Standard Operating Procedures: A Multicenter Study of 59 Patients.

M. Felcht, C. Klemke, L. van der Fits, 2016, The Journal of investigative dermatology.

MicroRNA expression in Sezary syndrome: identification, function, and diagnostic potential.

J. Chi, F. Pezzella, S. Whittaker, 2010, Blood.

The Genetic Architecture of the Human Immune System: A Bioresource for Autoimmunity and Disease Pathogenesis

Mario Roederer, Frank O. Nestle, Tim D. Spector, 2015, Cell.

Genetic defects causing familial hypercholesterolaemia: identification of deletions and duplications in the LDL-receptor gene and summary of all mutations found in patients attending the Hammersmith Hospital Lipid Clinic.

A. Soutar, R. Naoumova, C. Neuwirth, 2007, Atherosclerosis.

Elevated IgG4 in patient circulation is associated with the risk of disease progression in melanoma

Kristina M. Ilieva, I. Fentiman, J. Taylor‐Papadimitriou, 2015, Oncoimmunology.

Candidate driver genes involved in genome maintenance and DNA repair in Sézary syndrome.

M. Simpson, S. Whittaker, Charlotte E. Flanagan, 2016, Blood.

Constitutive activation of STAT3 in Sézary syndrome is independent of SHP-1

T. Mitchell, C. Jones, S. Whittaker, 2012, Leukemia.

The IL23R R381Q Gene Variant Protects against Immune-Mediated Diseases by Impairing IL-23-Induced Th17 Effector Response in Humans

K. Peris, F. Villanova, F. Nestle, 2011, PloS one.

Severe Hypercholesterolemia in Four British Families With the D374Y Mutation in the PCSK9 Gene: Long-Term Follow-Up and Treatment Response

S. Horswell, A. Marais, A. Soutar, 2005, Arteriosclerosis, thrombosis, and vascular biology.

Activation of the Aryl Hydrocarbon Receptor Dampens the Severity of Inflammatory Skin Conditions

Frank O. Nestle, Helena Ahlfors, Brigitta Stockinger, 2014, Immunity.

IgG subclass switching and clonal expansion in cutaneous melanoma and normal skin

Kristina M. Ilieva, F. Villanova, F. Nestle, 2016, Scientific Reports.

Independent Loss of Methylthioadenosine Phosphorylase (MTAP) in Primary Cutaneous T-Cell Lymphoma.

S. Whittaker, A. Lorenc, T. Mitchell, 2016, The Journal of investigative dermatology.

Contribution of STAT3 and RAD23B in Primary Sézary Cells to Histone Deacetylase Inhibitor FK228 Resistance.

S. Whittaker, Charlotte E. Flanagan, S. John, 2019, The Journal of investigative dermatology.

Pioglitazone added to conventional lipid-lowering treatment in familial combined hyperlipidaemia improves parameters of metabolic control: relation to liver, muscle and regional body fat content.

Jimmy D Bell, J. Fitzpatrick, Elizabeth Louise Thomas, 2007, Atherosclerosis.

Evidence for effect of mutant PCSK9 on apolipoprotein B secretion as the cause of unusually severe dominant hypercholesterolaemia.

David Wile, A. Soutar, R. Naoumova, 2005, Human molecular genetics.

White matter brain lesions in midlife familial hypercholesterolemic patients at 3-tesla magnetic resonance imaging

S. Schmitz, D. O’Regan, J. Hajnal, 2008, Acta radiologica.

The IL23R A/Gln381 Allele Promotes IL-23 Unresponsiveness in Human Memory T-Helper 17 Cells and Impairs Th17 Responses in Psoriasis Patients

J. Todd, S. Nutland, F. Villanova, 2013, The Journal of investigative dermatology.

MBTPS2 mutation in a British pedigree with keratosis follicularis spinulosa decalvans

J. Mellerio, E. Wedgeworth, A. Powell, 2012, Clinical and experimental dermatology.

Downregulation of Fas gene expression in Sézary syndrome is associated with promoter hypermethylation.

S. Whittaker, T. Mitchell, Chung-Ching Chu, 2010, The Journal of investigative dermatology.

Candidate driver genes involved in genome maintenance and DNA repair in Sézary syndrome.

M. Simpson, S. Whittaker, Charlotte E. Flanagan, 2016, Blood.