H. Böttcher

发表

Synthesis and in vitro and in vivo functional studies of ortho-substituted phenylpiperazine and N-substituted 4-N-(o-methoxyphenyl)aminopiperidine analogues of WAY100635.

H. Wikström, P. de Boer, G. Bartoszyk, 2000, Journal of medicinal chemistry.

EMD 281014, a new selective serotonin 5-HT2A receptor antagonist.

C. Seyfried, G. Bartoszyk, H. Böttcher, 2003, European journal of pharmacology.

SAR of novel biarylmethylamine dopamine D4 receptor ligands.

C. Seyfried, G. Bartoszyk, H. Böttcher, 1998, Bioorganic & medicinal chemistry letters.

Palladium-catalyzed carbonylation of haloindoles: no need for protecting groups.

D. Michalik, M. Beller, Kamal Kumar, 2004, Organic letters.

Synthesis and in vitro and in vivo functional studies of ortho-substituted phenylpiperazine and N-substituted 4-N-(o-methoxyphenyl)aminopiperidine analogues of WAY100635.

H. Wikström, P. de Boer, G. Bartoszyk, 2000, Journal of medicinal chemistry.

Syntheses of novel 2,3-diaryl-substituted 5-cyano-4-azaindoles exhibiting c-Met inhibition activity.

Michael Reggelin, T. Heinrich, Timo Heinrich, 2009, Bioorganic & medicinal chemistry letters.

New (sulfonyloxy)piperazinyldibenzazepines as potential atypical antipsychotics: chemistry and pharmacological evaluation.

H. Wikström, B. Venhuis, S. Sundell, 1999, Journal of medicinal chemistry.

A new synthesis of indole 5-carboxylic acids and 6-hydroxy-indole-5-carboxylic acids in the preparation of an o-hydroxylated metabolite of vilazodone.

T. Heinrich, H. Böttcher, 2004, Bioorganic & medicinal chemistry letters.

New selective and potent 5-HT(1B/1D) antagonists: chemistry and pharmacological evaluation of N-piperazinylphenyl biphenylcarboxamides and biphenylsulfonamides.

H. Wikström, J. März, S. Sundell, 2000, Journal of medicinal chemistry.

Palladium-catalyzed carbonylation of haloindoles: no need for protecting groups.

D. Michalik, M. Beller, Kamal Kumar, 2004, Organic letters.

Biologically active compounds through catalysis: efficient synthesis of N-(heteroarylcarbonyl)-N'-(arylalkyl)piperazines.

D. Michalik, M. Beller, Kamal Kumar, 2004, Chemistry.

5-HT reuptake inhibitors with 5-HT(1B/1D) antagonistic activity: a new approach toward efficient antidepressants.

C. Seyfried, L. Matzen, L Matzen, 2000, Journal of medicinal chemistry.

Synthesis of Substituted, Partially Hydrogenated [1,2,4]Triazino[4,5‐a]indoles and Pyrrolo[1,2‐d][1,2,4]triazines

H. Böttcher, B. Arzt, 1984 .

Allosteric IGF-1R Inhibitors.

U. Grädler, T. Heinrich, A. Blaukat, 2010, ACS medicinal chemistry letters.

1‐(1‐Phenethylpiperidin‐4‐yl)‐1‐phenylethanols as Potent and Highly Selective 5‐HT2A Antagonists

T. Heinrich, R. Gottschlich, H. Böttcher, 2006, ChemMedChem.

2-Alkyl-3-(1,2,3,6-tetrahydropyridin-4-yl)-1H-indoles as novel 5-HT6 receptor agonists.

H. Greiner, J. Leibrock, C. Sonesson, 2005, Bioorganic & medicinal chemistry letters.

Synthesis and Structure−Activity Relationship in a Class of Indolebutylpiperazines as Dual 5-HT1A Receptor Agonists and Serotonin Reuptake Inhibitors

S. Anzali, T. Heinrich, H. Greiner, 2004 .

Identification of benzothiazoles as potential polyglutamine aggregation inhibitors of Huntington's disease by using an automated filter retardation assay

H. Lehrach, E. Wanker, S. Waelter, 2002, Proceedings of the National Academy of Sciences of the United States of America.

Dual 5-HT1A agonists and 5-HT re-uptake inhibitors by combination of indole-butyl-amine and chromenonyl-piperazine structural elements in a single molecular entity.

T. Heinrich, H. Greiner, K. Schiemann, 2004, Bioorganic & medicinal chemistry.

Synthesis and dopaminergic activity of some 3-(1,2,3,6-tetrahydro-1-pyridylalkyl)indoles. A novel conformational model to explain structure-activity relationships.

G. Barnickel, C. Seyfried, V. Eiermann, 1992, Journal of Medicinal Chemistry.