B. Georgievska

发表

Reversal of motor impairments in parkinsonian rats by continuous intrastriatal delivery of l-dopa using rAAV-mediated gene transfer

A. Björklund, R. Mandel, N. Muzyczka, 2002, Proceedings of the National Academy of Sciences of the United States of America.

Cognitive changes and modified processing of amyloid precursor protein in the cortical and hippocampal system after cholinergic synapse loss and muscarinic receptor activation.

O. Isacson, A. Mattsson, B. Georgievska, 1999, Proceedings of the National Academy of Sciences of the United States of America.

Myeloperoxidase Inhibition Ameliorates Multiple System Atrophy-Like Degeneration in a Transgenic Mouse Model

W. Poewe, G. Wenning, N. Stefanova, 2012, Neurotoxicity Research.

Failure of Neuroprotection Despite Microglial Suppression by Delayed-Start Myeloperoxidase Inhibition in a Model of Advanced Multiple System Atrophy: Clinical Implications

R. J. Mather, W. Poewe, G. Wenning, 2015, Neurotoxicity Research.

Interactive report Towards a neuroprotective gene therapy for Parkinson's disease: use of adenovirus, AAV and lentivirus vectors for gene transfer of GDNF

A. Björklund, D. Kirik, C. Rosenblad, 2000 .

Failure of Neuroprotection Despite Microglial Suppression by Delayed-Start Myeloperoxidase Inhibition in a Model of Advanced Multiple System Atrophy: Clinical Implications

R. J. Mather, W. Poewe, G. Wenning, 2015, Neurotoxicity Research.

Seizure suppression by GDNF gene therapy in animal models of epilepsy.

M. Kokaia, D. Kirik, B. Georgievska, 2007, Molecular therapy : the journal of the American Society of Gene Therapy.

Early diagnosis and detection of clinically non‐suspected thyroid neoplasia by the cytologic method a critical review of 1536 aspiration biopsies

G. Stavrić, B. Karanfilski, B. Georgievska, 1980, Cancer.

Efficient transduction of neurons using Ross River glycoprotein-pseudotyped lentiviral vectors

C. Lundberg, J. Jakobsson, T. Nielsen, 2006, Gene Therapy.

Citation for the published paper: Ericson C, Georgievska B, Lundberg C. "Ex vivo gene delivery of GDNF using primary astrocytes transduced with a lentiviral vector provides neuroprotection in a rat model of Parkinson's disease."

C. Lundberg, B. Georgievska, Cecilia Ericson, 2006 .

Ex vivo gene delivery of GDNF using primary astrocytes transduced with a lentiviral vector provides neuroprotection in a rat model of Parkinson's disease

C. Lundberg, B. Georgievska, Cecilia Ericson, 2005, The European journal of neuroscience.

Regulated delivery of glial cell line-derived neurotrophic factor into rat striatum, using a tetracycline-dependent lentiviral vector.

D. Kirik, C. Lundberg, J. Jakobsson, 2004, Human gene therapy.

Continuous Low-Level Glial Cell Line-Derived Neurotrophic Factor Delivery Using Recombinant Adeno-Associated Viral Vectors Provides Neuroprotection and Induces Behavioral Recovery in a Primate Model of Parkinson's Disease

R. Ridley, H. Baker, L. Annett, 2005, The Journal of Neuroscience.

Overexpression of Glial Cell Line-Derived Neurotrophic Factor Using a Lentiviral Vector Induces Time- and Dose-Dependent Downregulation of Tyrosine Hydroxylase in the Intact Nigrostriatal Dopamine System

A. Björklund, D. Kirik, B. Georgievska, 2004, The Journal of Neuroscience.

Long‐term striatal overexpression of GDNF selectively downregulates tyrosine hydroxylase in the intact nigrostriatal dopamine system

D. Kirik, C. Rosenblad, B. Georgievska, 2003, The European journal of neuroscience.

Aberrant Sprouting and Downregulation of Tyrosine Hydroxylase in Lesioned Nigrostriatal Dopamine Neurons Induced by Long-Lasting Overexpression of Glial Cell Line Derived Neurotrophic Factor in the Striatum by Lentiviral Gene Transfer

A. Björklund, D. Kirik, B. Georgievska, 2002, Experimental Neurology.

Neuroprotection in the rat Parkinson model by intrastriatal GDNF gene transfer using a lentiviral vector

A. Björklund, D. Kirik, C. Rosenblad, 2002, Neuroreport.

Delayed infusion of GDNF promotes recovery of motor function in the partial lesion model of Parkinson's disease

A. Björklund, D. Kirik, C. Rosenblad, 2001, European Journal of Neuroscience.

Selective Antibody-Induced Cholinergic Cell and Synapse Loss Produce Sustained Hippocampal and Cortical Hypometabolism with Correlated Cognitive Deficits

Ling Lin, Ole Isacson, S. Browne, 2001, Experimental Neurology.

Dissociation between short‐term increased graft survival and long‐term functional improvements in Parkinsonian rats overexpressing glial cell line‐derived neurotrophic factor

D. Kirik, C. Winkler, T. Carlsson, 2004, The European journal of neuroscience.

Revisiting the peripheral sink hypothesis: inhibiting BACE1 activity in the periphery does not alter β‐amyloid levels in the CNS

U. Lendahl, S. Eketjäll, A. Juréus, 2015, Journal of neurochemistry.

GDNF fails to exert neuroprotection in a rat α-synuclein model of Parkinson's disease.

A. Björklund, B. Mattsson, D. Kirik, 2011, Brain : a journal of neurology.

Brain area, age and viral vector-specific glial cell-line-derived neurotrophic factor expression and transport in rat

M. Kokaia, D. Kirik, B. Georgievska, 2007, Neuroreport.

Localized striatal delivery of GDNF as a treatment for Parkinson disease

A. Björklund, D. Kirik, B. Georgievska, 2004, Nature Neuroscience.

AZD1080, a novel GSK3 inhibitor, rescues synaptic plasticity deficits in rodent brain and exhibits peripheral target engagement in humans

S. Hellberg, R. Bhat, P. Arvidsson, 2013, Journal of neurochemistry.

Continuous exposure to glial cell line-derived neurotrophic factor to mature dopaminergic transplants impairs the graft’s ability to improve spontaneous motor behavior in parkinsonian rats

D. Kirik, C. Winkler, T. Carlsson, 2006, Neuroscience.

Aminoimidazoles as BACE-1 inhibitors: the challenge to achieve in vivo brain efficacy.

Britt-Marie Swahn, Margareta Ek, Johan Lindström, 2012, Bioorganic & medicinal chemistry letters.

Myeloperoxidase Inhibition Ameliorates Multiple System Atrophy-Like Degeneration in a Transgenic Mouse Model

W. Poewe, G. Wenning, N. Stefanova, 2012, Neurotoxicity Research.

Design and synthesis of β-site amyloid precursor protein cleaving enzyme (BACE1) inhibitors with in vivo brain reduction of β-amyloid peptides.

Britt-Marie Swahn, Johan Lindström, Stefan Berg, 2012, Journal of medicinal chemistry.

Reversal of neurochemical changes and pain-related behavior in a model of neuropathic pain using modified lentiviral vectors expressing GDNF.

S. McMahon, S. Pezet, N. Mazarakis, 2006, Molecular therapy : the journal of the American Society of Gene Therapy.

Delivery of GDNF for Parkinson's Disease: Transition of a Neuroprotective Treatment Strategy From Basic Sciences to Clinical Application

C. Svendsen, D. Kirik, B. Georgievska, 2006 .

Combining an amyloid‐beta (Aβ) cleaving enzyme inhibitor with a γ‐secretase modulator results in an additive reduction of Aβ production

R. Cowburn, S. Eketjäll, P. Arvidsson, 2015, The FEBS journal.

Bace Inhibitors for the Treatment of Alzheimer's Disease

S. Eketjäll, B. Swahn, J. Fälting, 2009, Alzheimer's & Dementia.