Huilan Li

发表

Introduction of Z-GP scaffold into procarbazine reduces spermatoxicity and myelosuppression.

Rikang Wang, Yi Jin, Heru Chen, 2019, Bioorganic chemistry.

Design, synthesis, and biological evaluation of deuterated phenylpropionic acid derivatives as potent and long-acting free fatty acid receptor 1 agonists.

Wen-long Huang, Hai Qian, W. Shi, 2018, Bioorganic chemistry.

Design, synthesis and structure-activity relationship studies of novel free fatty acid receptor 1 agonists bearing amide linker.

Wen-long Huang, Hai Qian, W. Shi, 2017, Bioorganic & medicinal chemistry.

pH-Sensitive micelles with mitochondria-targeted and aggregation-induced emission characterization: synthesis, cytotoxicity and biological applications.

Wen-long Huang, Hai Qian, B. Zhang, 2018, Biomaterials science.

Improving metabolic stability with deuterium: The discovery of HWL‐066, a potent and long‐acting free fatty acid receptor 1 agonists

Wen-long Huang, Hai Qian, W. Shi, 2018, Chemical biology & drug design.

Improved antiproliferative activity of novel Pulsatilla saponin D/α-hederin derivatives containing nitric oxide donors

Yi Jin, Yulin Feng, Yuanying Fang, 2020 .

GPR119 agonists for the treatment of type 2 diabetes: an updated patent review (2014-present)

Yuanying Fang, Zunhua Yang, Huilan Li, 2021, Expert opinion on therapeutic patents.

Structure-Based Discovery of Pyrimidine Aminobenzene Derivatives as Potent Oral Reversal Agents against P-gp- and BCRP-Mediated Multidrug Resistance.

Wen-long Huang, Hai Qian, Ziyu Yin, 2021, Journal of medicinal chemistry.

Phenylquinoline transient receptor potential vanilloid 1 antagonists for the treatment of pain: Discovery of 1-(2-phenylquinoline-4-carbonyl)-N-(4-(trifluoromethyl)phenyl)pyrrolidine-3-carboxamide.

Wen-long Huang, Hai Qian, Huilan Li, 2017, Bioorganic & medicinal chemistry.

Val‐Val‐Tyr‐Pro protects against non‐alcoholic steatohepatitis in mice by modulating the gut microbiota and gut‐liver axis activation

Rikang Wang, Yi Jin, Yongbing Sun, 2021, Journal of cellular and molecular medicine.

Histology and antitumor activity study of PTX-loaded micelle, a fluorescent drug delivery system prepared by PEG-TPP

Wen-long Huang, Hai Qian, Wei Zhang, 2019, Chinese Chemical Letters.

Pro-apoptotic cationic host defense peptides rich in lysine or arginine to reverse drug resistance by disrupting tumor cell membrane

Wen-long Huang, Hai Qian, W. Shi, 2017, Amino Acids.

Novel 2,6-disubstituted benzofuran-3-one analogues improve cerebral ischemia/reperfusion injury via neuroprotective and antioxidative effects.

Yulin Feng, Yang Wan, Yuanying Fang, 2023, Bioorganic chemistry.

Synthesis and biological evaluation of novel aliphatic acid-conjugated antimicrobial peptides as potential agents with anti-tumor, multidrug resistance-reversing activity and enhanced stability

Wen-long Huang, Hai Qian, Liang Ge, 2017, Amino Acids.

Synthesis, Biological Evaluation, and Mode of Action of Pulsatilla Saponin D Derivatives as Promising Anticancer Agents

Yi Jin, Yuanying Fang, Shiling Yang, 2019, Frontiers in Pharmacology.

Discovery of phenylsulfonyl acetic acid derivatives with improved efficacy and safety as potent free fatty acid receptor 1 agonists for the treatment of type 2 diabetes.

Wen-long Huang, Hai Qian, W. Shi, 2017, European journal of medicinal chemistry.

Evaluation of novel paclitaxel-loaded NO-donating polymeric micelles for an improved therapy for gastroenteric tumor

Yi Jin, Yuanying Fang, Ronghua Liu, 2021, New Journal of Chemistry.

Design, synthesis and evaluation of a novel series of inhibitors reversing P‐glycoprotein‐mediated multidrug resistance

Wen-long Huang, Hai Qian, Qianqian Qiu, 2018, Chemical biology & drug design.

Pro-apoptotic cationic host defense peptides rich in lysine or arginine to reverse drug resistance by disrupting tumor cell membrane

Wen-long Huang, Hai Qian, W. Shi, 2017, Amino Acids.

Design, synthesis, and biological evaluation of thieno[2,3-d]pyrimidine derivatives as novel dual c-Met and VEGFR-2 kinase inhibitors.

Wen-long Huang, Hai Qian, Huilan Li, 2017, Bioorganic & medicinal chemistry.

Discovery of novel free fatty acid receptor 1 agonists bearing triazole core via click chemistry.

Wen-long Huang, Hai Qian, Huilan Li, 2016, Bioorganic & medicinal chemistry.

Synthesis and biological evaluation of novel aliphatic acid-conjugated antimicrobial peptides as potential agents with anti-tumor, multidrug resistance-reversing activity and enhanced stability

Wen-long Huang, Hai Qian, Liang Ge, 2017, Amino Acids.