B. Cordell

发表

Transgenic Mice Expressing Human β‐APP751, But Not Mice Expressing β‐APP695, Display Early Alzheimer's Disease‐like Histopathology a

L. Higgins, R. Catalano, D. Quon, 1993 .

Transgenic mice expressing human beta-APP751, but not mice expressing beta-APP695, display early Alzheimer's disease-like histopathology.

L. Higgins, R. Catalano, D. Quon, 1993, Annals of the New York Academy of Sciences.

Macrophage Colony-stimulating Factor Augments β-Amyloid-induced Interleukin-1, Interleukin-6, and Nitric Oxide Production by Microglial Cells*

G. Murphy, B. Cordell, Lan Yang, 1998, The Journal of Biological Chemistry.

Structure and processing of yeast precursor tRNAs containing intervening sequences

W. Rutter, H. Goodman, P. Valenzuela, 1978, Nature.

Purification and subunit composition of atrial natriuretic peptide receptor.

J. Lewicki, D. Schenk, J. G. Porter, 1987, Proceedings of the National Academy of Sciences of the United States of America.

tRNATrp as primer for RNA-directed DNA polymerase: structural determinants of function.

H. Goodman, R. Swanstrom, J. Bishop, 1979, The Journal of biological chemistry.

Alzheimer's disease: beta-amyloid precursor protein expression in plaques varies among cytoarchitectonic areas of the medial temporal lobe.

S. Salamat, L. Forno, L. Eng, 1991, Neuroscience Letters.

Alzheimer's disease: β-amyloid precursor protein expression in plaques varies among cytoarchitectonic areas of the medial temporal lobe

S. Salamat, J. Tinklenberg, L. Forno, 1991, Neuroscience Letters.

Positive and negative regulation of APP amyloidogenesis by sumoylation

Yu-Wang Liu, D. Quon, B. Cordell, 2002, Proceedings of the National Academy of Sciences of the United States of America.

Novel functional assay for proteases and modulators

Y. Liu, Yu-Wang Liu, B. Cordell, 2001, Molecular biotechnology.

Conversion of brain apolipoprotein E to an insoluble form in a mouse model of Alzheimer disease

K. Bales, Su Wu, S. Paul, 2001, Neuroreport.

Transgenic mouse brain histopathology resembles early Alzheimer's disease

D. Holtzman, W. Mobley, L. Higgins, 1994, Annals of neurology.

Selective reduction of mRNA for the β-amyloid precursor protein that lacks a Kunitz-type protease inhibitor motif in cortex from Alzheimer brains

Steven A. Johnson, C. Finch, G. Pasinetti, 1988, Experimental Neurology.

Glycogen Synthase Kinase-3β Regulates Presenilin 1 C-terminal Fragment Levels*

S. Hsu, F. Kirschenbaum, J. McCarthy, 2001, The Journal of Biological Chemistry.

p3 -Amyloid Peptide Has a Unique and Potentially Pathogenic Immunohistochemical Profile in Alzheimer's Disease Brain

G. Murphy, L. Higgins, R. Catalano, 2007 .

Isolation and characterization of the human pulmonary surfactant apoprotein gene

J. Schilling, S. Hawgood, B. Benson, 1985, Nature.

Morphological and Behavioral Effects of Basic Fibroblast Growth Factor and Heparin on Transplanted Fetal Dopaminergic Neurons and Astrocytes in the Denervated Rat Caudate-Putamen

H. Steinbusch, A. Nijssen, J. Vente, 1991 .

Early Alzheimer disease-like histopathology increases in frequency with age in mice transgenic for beta-APP751.

L. Higgins, R. Catalano, D. Quon, 1995, Proceedings of the National Academy of Sciences of the United States of America.

Relation of neuronal APP-751/APP-695 mRNA ratio and neuritic plaque density in Alzheimer's disease.

C. Finch, T. McNeill, B. Cordell, 1990, Science.

Growth hormone regulates expression of rat liver cytochrome P-450 15 beta at a pretranslational level.

J. Gustafsson, C. MacGeoch, E. Morgan, 1987, Biochemical and biophysical research communications.

Identification and characterization of C‐terminal fragments of the beta‐amyloid precursor produced in cell culture.

D. Wolf, Y. Wang, D. Quon, 1990, The EMBO journal.

At least 104 nucleotides are transposed from the 5′ terminus of the avian sarcoma virus genome to the 5′ termini of smaller viral mrnas

H. Varmus, J. Bishop, S. Weiss, 1978, Cell.

Accumulation of abundant messenger ribonucleic acids during postnatal development of mouse small intestine.

A. Ouellette, B. Cordell, A. J. Ouellette, 1988, Gastroenterology.

Polymorphism in the 5'-flanking region of the human insulin gene and its possible relation to type 2 diabetes.

J. Chirgwin, P. Rotwein, B. Cordell, 1981, Science.

Isolation and Characterization of Apolipoproteins from Murine Microglia

D. Sanan, Qiang Xu, B. Cordell, 2000, The Journal of Biological Chemistry.

A new A4 amyloid mRNA contains a domain homologous to serine protease inhibitors

B. Greenberg, I. Lieberburg, W. Wallace, 1988 .

Gene localization by chromosome fractionation: globin genes are on at least two chromosomes and three estrogen-inducible genes are on three chromosomes.

J. D. Engel, H. Varmus, J. Dodgson, 1979, Proceedings of the National Academy of Sciences of the United States of America.

Presenilin 1 Controls (cid:103) -Secretase Processing of Amyloid Precursor Protein in Pre-Golgi Compartments of Hippocampal Neurons

B. Strooper, D. Westaway, P. Fraser, 1999 .

Assigning the polymorphic human insulin gene to the short arm of chromosome 11 by chromosome sorting

A. Carrano, Y. Kan, R. Lebo, 2004, Human Genetics.

Secretion of beta-amyloid precursor protein involves multiple cleavage sites.

K. Murakami, Y. Wang, J. Higaki, 1994, The Journal of biological chemistry.

Alpha2 macroglobulin and the risk of Alzheimer's disease.

J. Yesavage, A. Pfefferbaum, S. Paul, 2000, Neurology.

Additional arrows for the β-amyloid target

B. Cordell, 1989, Neurobiology of Aging.

A combinatorial approach to the identification of dipeptide aldehyde inhibitors of beta-amyloid production.

P. Harden, J. Higaki, S. Chakravarty, 1999, Journal of medicinal chemistry.

Cytokine Communication Between Neurons and Glia and the Pathogenesis of Alzheimer’s Disease

S. Paul, K. Bales, G. Murphy, 2000 .

Nucleotide Sequence ThatBindsPrimerforDNA Synthesis totheAvianSarcoma VirusGenome

H. Goodman, R. Friedrich, E. Stavnezer, 1976 .

A Transgenic Mouse Model of Alzheimer’s Disease

L. Higgins, B. Cordell, 1994 .

Formation of beta-amyloid protein deposits in brains of transgenic mice.

K. Murakami, Y. Wang, J. Scardina, 1991, Nature.

Regulation of pulmonary surfactant apoprotein SP 28-36 gene in fetal human lung.

L. Gonzales, S. Hawgood, B. Cordell, 1986, Proceedings of the National Academy of Sciences of the United States of America.

Transgenic Mice as a Model of Alzheimer’s Disease

L. Higgins, B. Cordell, 1994 .

Development of a monoclonal antibody specific for the COOH-terminal of beta-amyloid 1-42 and its immunohistochemical reactivity in Alzheimer's disease and related disorders.

L. Forno, L. Eng, G. Murphy, 1994, The American journal of pathology.

Analysis of β-Amyloid Peptide Degradation In Vitro.

B. Cordell, A. Naidu, 2000, Methods in molecular medicine.

β-amyloid precursor detected in human cerebral cortex

J. Tinklenberg, L. Eng, W. Ellis, 1990, Progress in Neuro-Psychopharmacology and Biological Psychiatry.

Neuroinflammation and Alzheimer's disease: critical roles for cytokine/Abeta-induced glial activation, NF-kappaB, and apolipoprotein E.

S. Paul, K. Bales, D. Holtzman, 2000, Neurobiology of aging.

Striving for useful phenotypes in β-APP transgenic mice

L. Higgins, B. Cordell, 1995, Neurobiology of Aging.

Inhibition of amino acyl tRNA synthetase activity by copper complexes of two metal binding ligands. N-Methyl isatin beta-thiosemicarbazone and 8-hydroxyquinoline.

W. Rohde, W. Levinson, B. Cordell, 1977, Biochimica et biophysica acta.

Substitution of a Glycogen Synthase Kinase-3β Phosphorylation Site in Presenilin 1 Separates Presenilin Function from β-Catenin Signaling*

S. Hsu, F. Kirschenbaum, J. McCarthy, 2001, The Journal of Biological Chemistry.

Sequence of the human insulin gene

Howard M. Goodman, William J. Rutter, Graeme I. Bell, 1980, Nature.

Formation of β-amyloid protein deposits in brains of transgenic mice

K. Murakami, Y. Wang, J. Scardina, 1991, Nature.

Inhibition of β-amyloid formation identifies proteolytic precursors and subcellular site of catabolism

J. Higaki, D. Quon, B. Cordell, 1995, Neuron.

Pathology of early-onset Alzheimer's disease cases bearing the Thr113-114ins presenilin-1 mutation.

C. Morris, D. Rubinsztein, M. Cruts, 2000, Brain : a journal of neurology.

Presenilin 1 Controls γ-Secretase Processing of Amyloid Precursor Protein in Pre-Golgi Compartments of Hippocampal Neurons

B. de Strooper, D. Westaway, P. Fraser, 1999, The Journal of cell biology.

Phosphorylation, Subcellular Localization, and Membrane Orientation of the Alzheimer's Disease-associated Presenilins*

P. S. St George-Hyslop, B. de Strooper, M. Bollen, 1997, The Journal of Biological Chemistry.

Antibodies to presenilin proteins detect neurofibrillary tangles in Alzheimer's disease.

L. Forno, T. Bird, W. Ellis, 1996, The American journal of pathology.

Nucleotide and deduced amino acid sequence of the influenza neuraminidase genes of two equine serotypes.

G. Air, B. Dale, Rhonda Brown, 1986, Virology.

Nucleotide sequence that binds primer for DNA synthesis to the avian sarcoma virus genome

H. Goodman, J. Bishop, R. Friedrich, 1976, Journal of virology.

Isolation and characterization of a cloned rat insulin gene

W. Rutter, R. Pictet, E. Tischer, 1979, Cell.

Disproportionate expression of the two nonallelic rat insulin genes in a pancreatic tumor is due to translational control

H. Goodman, D. Diamond, B. Cordell, 1982, Cell.

A new A4 amyloid mRNA contains a domain homologous to serine proteinase inhibitors

B. Greenberg, I. Lieberburg, W. Wallace, 1988, Nature.

Secretion of apolipoprotein E by brain glia requires protein prenylation and is suppressed by statins

Qiang Xu, R. Catalano, B. Cordell, 2002, Brain Research.

Polymorphism in the 5' flanking region of the human insulin gene: a genetic marker for non-insulin-dependent diabetes.

M. Permutt, J. Chirgwin, W. Knowler, 1983, The New England journal of medicine.

Recombination within and between the human insulin and beta-globin gene loci.

H. Cann, K. Buetow, A. Chakravarti, 1983, Proceedings of the National Academy of Sciences of the United States of America.

Gene expression profile of the PDAPP mouse model for Alzheimer's disease with and without Apolipoprotein E

J. Yesavage, L. Lazzeroni, H. Ryan, 2009, Neurobiology of Aging.

Specific spatial learning deficits become severe with age in β-amyloid precursor protein transgenic mice that harbor diffuse β-amyloid deposits but do not form plaques

J. Bureš, J. Koistinaho, J. Cimadevilla, 2001, Proceedings of the National Academy of Sciences of the United States of America.

Transgenic Mice and Modeling Alzheimer's Disease

L. Higgins, B. Cordell, 1995, Reviews in the neurosciences.

Fibroblast growth factor induces beta-amyloid precursor mRNA in glial but not neuronal cultured cells.

R. Catalano, D. Quon, B. Cordell, 1990, Biochemical and biophysical research communications.

Synthesis and characterization of the Kunitz protease-inhibitor domain of the β-amyloid precursor protein

J. Schilling, Leanne M. Smith, K. Lau, 1991 .

beta-Amyloid formation as a potential therapeutic target for Alzheimer's disease.

B. Cordell, Barbara Cordell, 1994, Annual review of pharmacology and toxicology.

Neuronal DNA damage correlates with overexpression of interleukin-1β converting enzyme in APPV717F mice

S. Paul, W. Griffin, R. Mrak, 2001, Neurobiology of Aging.

P. Moran, L. Higgins, P. Moser, 1995, Proceedings of the National Academy of Sciences of the United States of America.

α2 Macroglobulin and the risk of Alzheimer’s disease

J. Yesavage, A. Pfefferbaum, S. Paul, 2000, Neurology.

Beta-amyloid precursor protein. Location of transmembrane domain and specificity of gamma-secretase cleavage.

E. Tischer, B. Cordell, 1996, The Journal of biological chemistry.

Nucleotide sequence of a cDNA clone encoding human preproinsulin

W. Rutter, R. Pictet, H. Goodman, 1979, Nature.

Early Phenotypic Changes in Transgenic Mice That Overexpress Different Mutants of Amyloid Precursor Protein in Brain*

Veerle Baekelandt, Emile Godaux, E. Godaux, 1999, The Journal of Biological Chemistry.

Expression of macrophage colony-stimulating factor receptor is increased in the AbetaPP(V717F) transgenic mouse model of Alzheimer's disease.

G. Murphy, F. Zhao, B. Cordell, 2000, The American journal of pathology.

Behavioral Disturbances without Amyloid Deposits in Mice Overexpressing Human Amyloid Precursor Protein with Flemish (A692G) or Dutch (E693Q) Mutation

C. Broeckhoven, P. Cras, F. Checler, 2000, Neurobiology of Disease.

Overexpression of the Neuritotrophic Cytokine S100β Precedes the Appearance of Neuritic β‐Amyloid Plaques in APPV717F Mice

W. Griffin, R. Mrak, K. Bales, 2000 .

Association of heparan sulfate proteoglycan with the neurofibrillary tangles of Alzheimer's disease

P. Cras, R. Kalaria, M. Kawai, 1991, The Journal of neuroscience : the official journal of the Society for Neuroscience.

Overexpression of the neuritotrophic cytokine S100beta precedes the appearance of neuritic beta-amyloid plaques in APPV717F mice.

S. Paul, R. Mrak, K. Bales, 2000, Journal of neurochemistry.

Protease-specificity of Kunitz inhibitor domain of Alzheimer's disease amyloid protein precursor.

N. Katunuma, H. Kido, A. Fukutomi, 1990, Biochemical and biophysical research communications.

Neuroinflammation and Alzheimer’s disease: critical roles for cytokine/Aβ-induced glial activation, NF-κB, and apolipoprotein E

D. Holtzman, S. Paul, K. Bales, 2000, Neurobiology of Aging.

The forms of tRNATrp found in avian sarcoma virus and uninfected chicken cells have structural identity but functional distinctions.

H. Goodman, J. F. Atkins, R. Gesteland, 1980, The Journal of biological chemistry.

Sequence and structural organization of the human gene encoding ciliary neurotrophic factor.

M. Manthorpe, S. Varon, A. Lam, 1991, Gene.

Processing of β-Amyloid Precursor Protein by Cathepsin D*

C. Tarnus, J. Higaki, A. Guzzetta, 1996, The Journal of Biological Chemistry.

Structural and functional characterization of the upstream regulatory region of the human gene encoding prostate apoptosis response factor-4.

S. Hsu, F. Kirschenbaum, J. McCarthy, 2002, Gene.

Increased amyloid production from aberrant beta-amyloid precursor proteins.

J. Higaki, L. Higgins, D. Quon, 1994, The Journal of biological chemistry.

Viruses as an aid to cancer therapy: regression of solid and ascites tumors in rodents after treatment with bovine enterovirus.

M. W. Taylor, B. Cordell, M. Souhrada, 1971, Proceedings of the National Academy of Sciences of the United States of America.

Expression cloning of neurotrophic factors using Xenopus oocytes

P. Ponte, A. Lam, F. Fuller, 1992, Journal of neuroscience research.

Presenilin-1 and -2 Are Molecular Targets for γ-Secretase Inhibitors*

Robert A. Copeland, David W. Robertson, Qian Wang, 2000, The Journal of Biological Chemistry.

β-Amyloid Peptide Secretion by a Microglial Cell Line Is Induced by β-Amyloid-(25–35) and Lipopolysaccharide*

G. Murphy, B. Cordell, A. Naidu, 1996, The Journal of Biological Chemistry.

Inhibition of β‐Amyloid Formation by Haloperidol: A Possible Mechanism for Reduced Frequency of Alzheimer's Disease Pathology in Schizophrenia

G. Murphy, J. Higaki, B. Cordell, 1997, Journal of neurochemistry.

Synthesis and evaluation of succinoyl-caprolactam γ-secretase inhibitors

Marcie A. Glicksman, M. Glicksman, D. Seiffert, 2006 .

Genetically engineered animal models of human neurodegenerative diseases.

L. Higgins, B. Cordell, 1995, Neurodegeneration : a journal for neurodegenerative disorders, neuroprotection, and neuroregeneration.

P3 beta-amyloid peptide has a unique and potentially pathogenic immunohistochemical profile in Alzheimer's disease brain.

L. Forno, G. Murphy, L. Higgins, 1996, The American journal of pathology.

-Amyloid Peptide Produced in Vitro Is Degraded by Proteinases Released by Cultured Cells (*)

D. Quon, B. Cordell, A. Naidu, 1995, The Journal of Biological Chemistry.

Structure of canine pulmonary surfactant apoprotein: cDNA and complete amino acid sequence.

J. Schilling, S. Hawgood, B. Benson, 1985, Proceedings of the National Academy of Sciences of the United States of America.

β-Amyloid Precursor Protein

E. Tischer, B. Cordell, 1996, The Journal of Biological Chemistry.

Amyloid forming proteases: therapeutic targets for Alzheimer's disease.

J. Higaki, B. Cordell, Frauke Schimmöller, 2002, Current pharmaceutical design.

Substitution of a glycogen synthase kinase-3beta phosphorylation site in presenilin 1 separates presenilin function from beta-catenin signaling.

S. Hsu, F. Kirschenbaum, J. McCarthy, 2001, The Journal of biological chemistry.

Glycogen synthase kinase-3beta regulates presenilin 1 C-terminal fragment levels.

F. Kirschenbaum, J. McCarthy, B. Cordell, 2001, The Journal of biological chemistry.

Detection of insulin synthesis in mammalian anterior pituitary cells by immunohistochemistry and demonstration of insulin-related transcripts by in situ RNA-DNA hybridization.

B. Pansky, G. Budd, B. Cordell, 1986, The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society.

β-App-751 Transgenic Mice: Deficits in Learning and Memory

P. Moran, L. Higgins, P. Moser, 1997 .

A Transgenic Mouse Model of Alzheimer’s Disease

L. Higgins, B. Cordell, 1994 .