Toshihiro Sakamoto

发表

Discovery of imidazo[1,2-a]pyridines as potent MCH1R antagonists.

H. Iwaasa, S. Sakuraba, A. Kanatani, 2009, Bioorganic & medicinal chemistry letters.

Investigation of Bioequivalence Between Brand-name and Generic Irinotecan Products.

Y. Sasaki, Ken-Ichi Fujita, Y. Ikegami, 2016, Anticancer research.

Discovery of trans-N-[1-(2-fluorophenyl)-3-pyrazolyl]-3-oxospiro[6-azaisobenzofuran-1(3H),1'-cyclohexane]-4'-carboxamide, a potent and orally active neuropeptide Y Y5 receptor antagonist.

H. Iwaasa, M. Ando, M. Ishikawa, 2009, Bioorganic & medicinal chemistry.

Identification of positron emission tomography ligands for NPY Y5 receptors in the brain.

H. Iwaasa, T. Ohe, A. Kanatani, 2009, Bioorganic & medicinal chemistry letters.

Discovery of novel spiro-piperidine derivatives as highly potent and selective melanin-concentrating hormone 1 receptor antagonists.

H. Iwaasa, M. Ishikawa, A. Kanatani, 2009, Bioorganic & medicinal chemistry letters.

Small-molecule inhibition of Wee1 kinase by MK-1775 selectively sensitizes p53-deficient tumor cells to DNA-damaging agents

Tsuyoshi Arai, Hiroshi Hirai, Takashi Yoshizumi, 2009, Molecular Cancer Therapeutics.

Total synthesis of (±)-furoscrobiculin B

K. Kanematsu, H. Suemune, Toshihiro Sakamoto, 1997 .

Convenient synthesis of 2-alkylamino-6-carboxy-5,7-diarylcyclopenteno[1,2-b]pyridines via direct acylamination with imidoyl chlorides

T. Hayama, T. Fukami, T. Nishimura, 2005 .

Structure-activity relationships of a novel class of endothelin receptor selective antagonists; 6-carboxy-2-isopropylamino-5,7-diarylcyclopenteno[1,2-b]pyridines.

N. Kawanishi, T. Hayama, S. Ozaki, 2004, Bioorganic & medicinal chemistry letters.

Identification of 2-aminobenzimidazoles as potent melanin-concentrating hormone 1-receptor (MCH1R) antagonists.

H. Iwaasa, S. Sakuraba, A. Kanatani, 2009, Bioorganic & medicinal chemistry letters.

Identification and characterization of a selective radioligand for melanin-concentrating hormone 1-receptor (MCH1R).

H. Iwaasa, H. Matsushita, D. Dean, 2009, Bioorganic & medicinal chemistry letters.

Aryl urea derivatives of spiropiperidines as NPY Y5 receptor antagonists.

H. Iwaasa, T. Ohe, A. Kanatani, 2009, Bioorganic & medicinal chemistry letters.

Identification of novel and orally active spiroindoline NPY Y5 receptor antagonists.

D. Macneil, H. Iwaasa, A. Kanatani, 2009, Bioorganic & Medicinal Chemistry Letters.

Novel orally active NPY Y5 receptor antagonists: Synthesis and structure-activity relationship of spiroindoline class compounds.

H. Iwaasa, A. Kanatani, T. Fukami, 2009, Bioorganic & medicinal chemistry.

Total syntheses of spongiaditerpenoids: Spongia-13(16),14-diene and spongiadiosphenol☆

K. Kanematsu, Toshihiro Sakamoto, 1995 .

Synthetic strategy for construction of the furanohydrophenanthrene ring system

K. Kanematsu, Y. Baba, Toshihiro Sakamoto, 1994 .

Synthetic Strategy for Construction of the Furanohydrophenanthrene Ring System.

K. Kanematsu, Y. Baba, Toshihiro Sakamoto, 1994 .

Total Syntheses of Spongiaditerpenoids: Spongia-13(16),14-diene and Spongiadiosphenol.

K. Kanematsu, Toshihiro Sakamoto, 1995 .

Alternative synthetic approaches to (±)-euryfuran via the furan ring transfer reaction

K. Kanematsu, Toshihiro Sakamoto, Seizo Soejima, 1994 .

Potent and orally active ET(A) selective antagonists with 5,7-diarylcyclopenteno[1,2-b]pyridine-6-carboxylic acid structures.

T. Hayama, S. Ozaki, Y. Shibata, 2004, Bioorganic & medicinal chemistry.

Aryl urea derivatives of spiropiperidines as NPY Y5 receptor antagonists.

H. Iwaasa, T. Ohe, A. Kanatani, 2009, Bioorganic & medicinal chemistry letters.