Kenneth M Meyers

Aminomethyl tetrahydronaphthalene biphenyl carboxamide MCH-R1 antagonists--Increasing selectivity over hERG.

O. Reizes, S. Mittelstadt, S. R. Klopfenstein, 2007, Bioorganic & medicinal chemistry letters.

Design and synthesis of substituted quinolines as novel and selective melanin concentrating hormone antagonists as anti-obesity agents.

C. Mitchell, O. Reizes, J. Méndez-Andino, 2006, Bioorganic & medicinal chemistry letters.

Structure-based discovery of potent WD repeat domain 5 inhibitors that demonstrate efficacy and safety in preclinical animal models

S. Fesik, Qi Liu, S. Chowdhury, 2022, Proceedings of the National Academy of Sciences of the United States of America.

Discovery of Potent Orally Bioavailable WD Repeat Domain 5 (WDR5) Inhibitors Using a Pharmacophore-Based Optimization.

S. Fesik, J. Sai, Bin Zhao, 2022, Journal of medicinal chemistry.

Discovery and Structure-Based optimization of potent and selective WDR5 inhibitors containing a dihydroisoquinolinone bicyclic core

S. Fesik, R. Coffey, J. Sai, 2020 .

Discovery and Structure-Based Optimization of Potent and Selective WD repeat domain 5 (WDR5) Inhibitors Containing a Dihydroisoquinolinone Bicyclic Core.

S. Fesik, R. Coffey, M. Inoue, 2019, Journal of medicinal chemistry.

Identification of substituted 4-aminopiperidines and 3-aminopyrrolidines as potent MCH-R1 antagonists for the treatment of obesity.

O. Reizes, A. Colson, Jan R Davis, 2006, Bioorganic & medicinal chemistry letters.

The efficacy and cardiac evaluation of aminomethyl tetrahydronaphthalene ketopiperazines: a novel class of potent MCH-R1 antagonists.

M. Dowty, O. Reizes, C. Obringer, 2007, Bioorganic & medicinal chemistry.

Novel pyrazolopiperazinone- and pyrrolopiperazinone-based MCH-R1 antagonists.

M. Dowty, O. Reizes, C. Obringer, 2007, Bioorganic & medicinal chemistry letters.

Aminomethyl tetrahydronaphthalene ketopiperazine MCH-R1 antagonists--Increasing selectivity over hERG.

M. Dowty, O. Reizes, C. Obringer, 2007, Bioorganic & medicinal chemistry letters.