M. Grizzle

发表

Novel benzimidazole-based MCH R1 antagonists.

M. J. Bishop, J. Speake, A. Goetz, 2006, Bioorganic & medicinal chemistry letters.

Hemodynamic effects of GI 87084B, an ultra-short acting mu-opioid analgesic, in anesthetized dogs.

M. K. James, M. Grizzle, A. Vuong, 1992, The Journal of pharmacology and experimental therapeutics.

Food intake inhibition and reduction in body weight gain in lean and obese rodents treated with GW438014A, a potent and selective NPY-Y5 receptor antagonist

A. Daniels, D. Heyer, M. Grizzle, 2002, Regulatory Peptides.

3-(1H-indazol-3-ylmethyl)-1,5-benzodiazepines: CCK-A agonists that demonstrate oral activity as satiety agents.

M. K. James, T. Willson, B. Henke, 1996, Journal of medicinal chemistry.

Effects of a potent melanocortin agonist on the diabetic/obese phenotype in yellow mice

C. Harris, M. Grizzle, W. Wilkison, 1998, International Journal of Obesity.

Optimization of 3-(1H-indazol-3-ylmethyl)-1,5-benzodiazepines as potent, orally active CCK-A agonists.

M. K. James, T. Willson, B. Henke, 1997, Journal of medicinal chemistry.

1,4-Benzodiazepine peripheral cholecystokinin (CCK-A) receptor agonists.

M. K. James, T. Rimele, R. G. Sherrill, 2001, Bioorganic & medicinal chemistry letters.

Food intake inhibition and reduction in body weight gain in rats treated with GI264879A, a non-selective NPY-Y1 receptor antagonist

W. Chance, D. Heyer, M. Grizzle, 2001, Peptides.

Discovery of 1,5-benzodiazepines with peripheral cholecystokinin (CCK-A) receptor agonist activity (II): Optimization of the C3 amino substituent.

M. K. James, T. Willson, B. Henke, 1996, Journal of medicinal chemistry.

The discovery and optimization of pyrimidinone-containing MCH R1 antagonists.

M. J. Bishop, A. Goetz, F. Tavares, 2006, Bioorganic & medicinal chemistry letters.

Discovery of 1,5-benzodiazepines with peripheral cholecystokinin (CCK-A) receptor agonist activity. 1. Optimization of the agonist "trigger".

M. K. James, L. Miller, R. Carr, 1996, Journal of medicinal chemistry.

A concise synthesis of 1,4-dihydro-[1,4]diazepine-5,7-dione, a novel 7-TM receptor ligand core structure with melanocortin receptor agonist activity.

C. Laudeman, J. Szewczyk, D. Ignar, 2010, Bioorganic & medicinal chemistry.

Effect of polyethylene glycol-superoxide dismutase and catalase on endotoxemia in pigs.

N. Olson, M. Grizzle, D. Anderson, 1987, Journal of applied physiology.

6-Azasteroids: Potent Dual Inhibitors of Human Type 1 and 2 Steroid 5. alpha.-Reductase.

M. K. James, S. Frye, T. Tippin, 1994 .

Potent, selective, and orally efficacious antagonists of melanin-concentrating hormone receptor 1.

M. J. Bishop, A. Goetz, F. Tavares, 2006, Journal of medicinal chemistry.

Dimethylthiourea attenuates endotoxin-induced acute respiratory failure in pigs.

N. Olson, M. Grizzle, D. Anderson, 1987, Journal of applied physiology.

Effects of ketanserin on pulmonary hemodynamics, lung mechanics, and gas exchange in endotoxemic pigs.

N. Olson, M. Grizzle, D. Anderson, 1986, American journal of veterinary research.

Characterisation of olanzapine-induced weight gain and effect of aripiprazole vs olanzapine on body weight and prolactin secretion in female rats

D. Ignar, Claire Rourke, M. Kalinichev, 2005, Psychopharmacology.

6-(4-chlorophenyl)-3-substituted-thieno[3,2-d]pyrimidin-4(3H)-one-based melanin-concentrating hormone receptor 1 antagonist.

M. J. Bishop, A. Goetz, F. Tavares, 2006, Journal of medicinal chemistry.

Discovery of 1,5‐Benzodiazepines with Peripheral Cholecystokinin (CCK‐ A) Receptor Agonist Activity (II): Optimization of the C3 Amino Substituent.

T. Willson, B. Henke, J. Szewczyk, 1997 .

Modification of receptor selectivity and functional activity in cholecystokinin peptoid ligands.

M. K. James, J. Mosher, M. Grizzle, 1995, Journal of medicinal chemistry.