W. Park

发表

Development of a time-resolved fluorometric assay for the high throughput screening of melanin concentrating hormone receptor antagonists.

Gun-Do Kim, S. Yoo, Sunghou Lee, 2006, Journal of pharmacological and toxicological methods.

Differential effect of 5-hydroxytryptophan on approach and avoidance behavior in rats

M. H. Aprison, J. Hingtgen, W. Park, 1991, Pharmacology Biochemistry and Behavior.

In vitro BACE-1 inhibitory activity of resveratrol oligomers from the seed extract of Paeonia lactiflora.

S. Ryu, Young Sup Kim, Y. H. Kim, 2011, Planta medica.

Novel quinazolinone derivatives as 5-HT7 receptor ligands.

H. Choo, Y. Cho, H. Koh, 2008, Bioorganic & medicinal chemistry.

Preparation of piperazine derivatives as 5-HT7 receptor antagonists.

H. Rhim, A. Pae, W. Park, 2008, Bioorganic & medicinal chemistry.

KKHA-761, a potent D3 receptor antagonist with high 5-HT1A receptor affinity, exhibits antipsychotic properties in animal models of schizophrenia

H. Koh, A. Pae, W. Park, 2005, Pharmacology Biochemistry and Behavior.

Versatile Synthesis of Disubstituted Triazole Library for Dopamine and Serotonin Receptor Ligands

H. Koh, Hee‐Yoon Lee, W. Park, 2011 .

Design and synthesis of novel arylpiperazine derivatives containing the imidazole core targeting 5-HT(2A) receptor and 5-HT transporter.

Min Ju Kim, Jinhwa Lee, H. Seo, 2011, Journal of medicinal chemistry.

Naphthofuroquinone derivatives: inhibition of receptor tyrosine kinases.

Gun-Do Kim, J. Hwang, Su-Jin Park, 2006, Bioorganic & medicinal chemistry letters.

Inhibition of c-Kit signaling by diosmetin isolated from Chrysanthemum morifolium

G. Choi, W. Park, Heeyeong Cho, 2013, Archives of pharmacal research.

Discovery of thienopyrrolotriazine derivatives to protect mitochondrial function against Aβ-induced neurotoxicity.

Ashwini M. Londhe, Seo Yun Jung, Ki Duk Park, 2017, European journal of medicinal chemistry.

Synthesis and structure-activity relationship of 1H-indole-3-carboxylic acid pyridine-3-ylamides: a novel series of 5-HT2C receptor antagonists.

So Young Kim, So young Kim, So Young Kim, 2008, Bioorganic & medicinal chemistry letters.

Discovery of 4-(phenyl)thio-1H-pyrazole derivatives as agonists of GPR109A, a high affinity niacin receptor

Sunkyung Lee, J. Song, V. B. Jadhav, 2015, Archives of pharmacal research.

Discovery of GSK3β Inhibitors through In Silico Prediction-and-Experiment Cycling Strategy, and Biological Evaluation

Yuno Lee, Sunkyung Lee, Hyowon Hong, 2022, Molecules.

Screening of Kit inhibitors: suppression of Kit signaling and melanogenesis by emodin

G. Choi, Sangjin Kang, W. Park, 2009, Phytotherapy research : PTR.

Sphingosylphosphorylcholine Attenuated β–Amyloid Production by Reducing BACE1 Expression and Catalysis in PC12 Cells

C. Myung, W. Park, Heeyeong Cho, 2011, Neurochemical Research.

Synthesis and antioxidant activities of 3,5-dialkoxy-4-hydroxycinnamamides.

Y. Konishi, Jong-Pyung Kim, Young-Sik Jung, 2008, Bioorganic & medicinal chemistry letters.

Ginsenoside Rg3 antagonizes NMDA receptors through a glycine modulatory site in rat cultured hippocampal neurons.

S. Nah, H. Rhim, Sunoh Kim, 2004, Biochemical and biophysical research communications.

Identification of substituted pyrazole constrained arylpiperazines asselective ligands for serotonin 5HT 1a and 5HT 2a receptors

H. Koh, Jeeyeon Kim, Hee‐Yoon Lee, 2011 .

Synthesis and Biological Evaluation of Focused Isoxazolylpiperidinylpiperazine Library for Dopamine D3 and D4 Receptor Antagonists.

H. Koh, A. Pae, W. Park, 2011 .

Pharmacological actions of a novel and selective dopamine D3 receptor antagonist, KCH-1110.

Y. Cho, H. Koh, A. Pae, 2003, Pharmacological research.

Effect ofPanax ginseng on the development of morphine induced tolerance and dependence (VI). On the oral administration of ginseng ether fraction and saponins

K. Oh, W. Park, H. Kim, 1987 .

5-HT₂c receptor selectivity and structure-activity relationship of N-methyl-N-(1-methylpiperidin-4-yl)benzenesulfonamide analogs.

Y. Cho, A. Pae, Jae Wan Jang, 2012, Bioorganic & medicinal chemistry letters.

Construction of a Library of Arylpiperazinyl 1,2,3-Triazole Derivatives as Ligands for Dopamine D3/D4 Receptor

H. Koh, Hee‐Yoon Lee, R. Murugan, 2013 .

Synthesis of Piperazinylalkylisoxazoline Analogues and Their Binding Affinities for Dopamine Receptor Subtypes

H. Koh, A. Pae, Ji-Young Jung, 2006 .

In vitro BACE-1 Inhibitory Phenolic Components from the Seeds of Psoralea corylifolia

S. Ryu, Young Sup Kim, C. Choi, 2008, Planta medica.

A novel IRAK4/PIM1 inhibitor ameliorates rheumatoid arthritis and lymphoid malignancy by blocking the TLR/MYD88-mediated NF-κB pathway

C. Myung, Hyowon Hong, C. Chae, 2022, Acta pharmaceutica Sinica. B.

Discovery of 3-aryl-3-methyl-1H-quinoline-2,4-diones as a new class of selective 5-HT6 receptor antagonists.

Jae Yang Kong, Churl Min Seong, Woo Kyu Park, 2008, Bioorganic & medicinal chemistry letters.

Further optimization of novel pyrrole 3-carboxamides for targeting serotonin 5-HT(2A), 5-HT(2C), and the serotonin transporter as a potential antidepressant.

Min Ju Kim, A. Pae, Jinhwa Lee, 2010, Bioorganic & medicinal chemistry.

Synthesis and biological properties of 4-substituted quinolin-2(1H)-one analogues

Seikwan Oh, O. Park, Jae-chul Jung, 2003 .

Discovery of potent and selective cytotoxic activity of new quinazoline-ureas against TMZ-resistant glioblastoma multiforme (GBM).

Ambily Nath Indu Viswanath, H. Seol, D. Nam, 2015, European journal of medicinal chemistry.

Synthesis and SAR of (piperazin-1-yl-phenyl)-arylsulfonamides: a novel series of atypical antipsychotic agents.

So Young Kim, C. Park, C. Seong, 2010, Bioorganic & medicinal chemistry letters.

1-(Arylsulfonyl)-2,3-dihydro-1H-quinolin-4-one derivatives as 5-HT(6) serotonin receptor ligands.

So Young Kim, C. Park, C. Seong, 2011, Bioorganic & medicinal chemistry letters.

N-(2,7-dimethyl-2-alkyl-2H-chromen-6-yl)sulfonamide derivatives as selective serotonin 5-HT6 receptor antagonists: Design, synthesis, and biological evaluation

Aizhan Abdildinova, Y. Gong, W. Park, 2022, Journal of Molecular Structure.

Design, synthesis, biological evaluation and molecular modelling of 2‐(2‐aryloxyphenyl)‐1,4‐dihydroisoquinolin‐3(2H)‐ones: A novel class of TSPO ligands modulating amyloid‐&bgr;‐induced mPTP opening

Ki Duk Park, Jiyoun Lee, Bongjin Moon, 2017, European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences.

Blockade by naloxone of cocaine-induced hyperactivity, reverse tolerance and conditioned place preference in mice

C. Jang, Seikwan Oh, K. Oh, 1997, Behavioural Brain Research.

Cocaine Administered into the Medial Prefrontal Cortex Reinstates Cocaine-Seeking Behavior by Increasing AMPA Receptor-Mediated Glutamate Transmission in the Nucleus Accumbens

R D Spealman, R. Spealman, A. Bari, 2002, The Journal of Neuroscience.

KRICT-9 inhibits neuroinflammation, amyloidogenesis and memory loss in Alzheimer’s disease models

J. Hong, M. Park, S. Han, 2017, Oncotarget.

A new specific BACE-1 inhibitor from the stembark extract of Vitis vinifera.

S. Ryu, Young Sup Kim, C. Choi, 2009, Planta medica.

Synthesis and evaluation of 4-hydroxyphenylacetic acid amides and 4-hydroxycinnamamides as antioxidants.

Woo-Kyu Park, No-Sang Park, Young-Sik Jung, 2002, Bioorganic & medicinal chemistry letters.

Synthesis and Evaluation of a Series of 3,4,5‐Trimethoxycinnamic Acid Derivatives as Potential Antinarcotic Agents

Seikwan Oh, Jae-chul Jung, M. Jung, 2013, Chemical biology & drug design.

Modulation of the activity of pro-inflammatory enzymes, COX-2 and iNOS, by chrysin derivatives.

Woo-Kyu Park, Cheol-Won Yun, Youmie Park, 2004, Pharmacological research.

NMDA receptor antagonists inhibit apomorphine-induced climbing behavior not only in intact mice but also in reserpine-treated mice

Seikwan Oh, W. Park, G. Rhee, 1999, Behavioural Brain Research.

Synthesis and biological evaluation of 3-aminopyrrolidine derivatives as CC chemokine receptor 2 antagonists.

Seung-Woo Lee, M. Oak, G. Choi, 2010, Bioorganic & Medicinal Chemistry Letters.

Inhibitory effect of the root ofCoptis japonica on catecholamine biosynthesis in PC12 cells

Myung-Koo Lee, W. Park, H. Kim, 1994 .

Discovery of a Novel 2,6-Difunctionalized 2H-Benzopyran Inhibitors Toward Sphingosylphosphorylcholine Synthetic Pathway as New Anti-inflammatory Target

Y. Gong, W. Park, Heeyeong Cho, 2014 .

Inhibition of c-Kit signaling by diosmetin isolated from Chrysanthemum morifolium

G. Choi, W. Park, Heeyeong Cho, 2013, Archives of pharmacal research.

Neuregulin 1 Controls Glutamate Uptake by Up-regulating Excitatory Amino Acid Carrier 1 (EAAC1)*

Hye-Sun Kim, K. Nam, W. Park, 2015, The Journal of Biological Chemistry.

Indatraline inhibits Rho- and calcium-mediated glioblastoma cell motility and angiogenesis.

W. Park, Heeyeong Cho, Jin-Chul Heo, 2014, Biochemical and biophysical research communications.

Synthesis of (3S,4S)-4-aminopyrrolidine-3-ol derivatives and biological evaluation for their BACE1 inhibitory activities.

W. Park, Heeyeong Cho, Sukumar Bepary, 2016, Bioorganic & medicinal chemistry letters.

Biological evaluation of tanshindiols as EZH2 histone methyltransferase inhibitors.

Byung Jin Byun, J. Y. Lee, S. Ryu, 2014, Bioorganic & medicinal chemistry letters.

Derivatives of 3, 4, 5-Trimethoxycinnamic Acid Ameliorate Stress-Induced Anxiety in Mice and Rats

Hyun Kyu Min, Sun Mi Gu, Seikwan Oh, 2023, Molecular Neurobiology.

Nitric oxide mediation of cocaine-induced dopaminergic behaviors: ambulation-accelerating activity, reverse tolerance and conditioned place preference in mice.

W. Park, H. S. Kim, 1995, The Journal of pharmacology and experimental therapeutics.

Inhibition by MK-801 of cocaine-induced sensitization, conditioned place preference, and dopamine-receptor supersensitivity in mice

C. Jang, Seikwan Oh, W. Park, 1996, Brain Research Bulletin.

Inhibition by noncompetitive NMDA receptor antagonists of apomorphine-induced climbing behavior in mice.

C. Jang, J. H. Lee, J. Jung, 1996, Life sciences.

N‐Methyl‐d‐aspartate Receptor Antagonists Enhance the Head‐twitch Response, a 5‐Hydroxytryptamine2 Receptor‐mediated Behaviour, in Reserpine‐treated Mice

C. Jang, Seikwan Oh, W. Park, 2000, The Journal of pharmacy and pharmacology.

Suppression of NFAT5-mediated Inflammation and Chronic Arthritis by Novel κB-binding Inhibitors

D. Jue, Wan-Uk Kim, C. Cho, 2017, EBioMedicine.

Synthesis and Biological Evaluation of 3-Amino-4-aryl-piperidine Derivatives as BACE 1 Inhibitors

W. Park, Hee-Jong Lim, M. Jung, 2006 .

A New Amaryllidaceae Alkaloid from the Bulbs of Lycoris radiata

Jin-hee Kim, Ji-Young Lee, S. Ryu, 2014 .

Inhibition by MK-801 of morphine-induced conditioned place preference and postsynaptic dopamine receptor supersensitivity in mice

C. Jang, W. Park, H. Kim, 1996, Pharmacology Biochemistry and Behavior.

Synthesis and biological evaluation of 4-nitroindole derivatives as 5-HT2A receptor antagonists.

Ambily Nath Indu Viswanath, H. Rhim, A. Pae, 2015, Bioorganic & medicinal chemistry.

Synthesis of 5‐(4‐Alkylsulfanyl‐[1, 2, 5]Thiadiazol‐3‐yl)‐3‐Methyl‐1, 2, 3, 4‐Tetrahydropyrimidine Oxalate Salts and their Evaluation as Muscarinic Receptor Agonists

W. Park, M. Jung, Jewn‐Giew Park, 2000, Archiv der Pharmazie.

Evaluation of anti-depressant effects of phthalazinone-based triple-acting small molecules against 5-HT2A, 5-HT2C, and the serotonin transporter.

A. Pae, Jihye Kim, W. Park, 2019, Bioorganic & medicinal chemistry letters.

The bis benzylisoquinoline alkaloids, tetrandine and fangchinoline, enhance the cytotoxicity of multidrug resistance‐related drugs via modulation of P‐glycoprotein

Sang-Un Choi, W. Park, H. Kim, 1998, Anti-cancer drugs.

Synthesis of Piperazinylalkylisoxazoline Analogues and Their Binding Affinities for Dopamine Receptor Subtypes.

H. Koh, A. Pae, Ji-Young Jung, 2007 .

Arylpiperazine-containing pyrrole 3-carboxamide derivatives targeting serotonin 5-HT(2A), 5-HT(2C), and the serotonin transporter as a potential antidepressant.

Min Ju Kim, A. Pae, Jinhwa Lee, 2010, Bioorganic & medicinal chemistry letters.

NMDA receptor antagonists enhance 5-HT2 receptor-mediated behavior, head-twitch response, in mice.

W. Park, H. S. Kim, I. Park, 1998, Life sciences.

Synthesis and biological evaluation of (phenylpiperazinyl-propyl)arylsulfonamides as selective 5-HT(2A) receptor antagonists.

H. Rhim, A. Pae, W. Park, 2010, Bioorganic & medicinal chemistry.

Evaluation of the Caffeine Contents in Tea and Coffee by HPLC and Effect of Caffeine on Behavior in Rats

K. Kwon, Bimit Mahat, Byung-yo Lee, 2012 .

Novel pyrimidoazepine analogs as serotonin 5-HT(2A) and 5-HT(2C) receptor ligands for the treatment of obesity.

Jiyoun Lee, Y. Cho, A. Pae, 2013, European journal of medicinal chemistry.

Synthesis and Biological Activities of (4-Arylpiperazinyl)piperidines as Nonpeptide BACE 1 Inhibitors.

W. Park, Hee-Jong Lim, Sun-Woo Won, 2011 .

Effects of ginseng total saponin on morphine-induced hyperactivity and conditioned place preference in mice

C. Jang, Seikwan Oh, K. Oh, 1998 .

Identification of novel serotonin 2C receptor ligands by sequential virtual screening.

Hyunah Choo, Yong Seo Cho, Ae Nim Pae, 2009, Bioorganic & medicinal chemistry.

Discovery of 4-(phenyl)thio-1H-pyrazole derivatives as agonists of GPR109A, a high affinity niacin receptor

Sunkyung Lee, J. Song, V. B. Jadhav, 2015, Archives of pharmacal research.

Novel N-biphenyl-2-ylmethyl 2-methoxyphenylpiperazinylalkanamides as 5-HT7R antagonists for the treatment of depression.

H. Choo, H. Rhim, G. Keum, 2014, Bioorganic & Medicinal Chemistry.

New Serotonin 5-HT6 Ligands from Common Feature Pharmacophore Hypotheses

Hyunah Choo, Yong Seo Cho, Ae Nim Pae, 2008, J. Chem. Inf. Model..

Synthesis of 5‐(4‐Alkylsulfanyl‐[1, 2, 5]Thiadiazol‐3‐yl)‐3‐Methyl‐1, 2, 3, 4‐Tetrahydropyrimidine Oxalate Salts and their Evaluation as Muscarinic Receptor Agonists

W. Park, M. Jung, Jewn‐Giew Park, 2000, Archiv der Pharmazie.

Identification of novel serotonin 2C receptor ligands by sequential virtual screening.

Y. Cho, A. Pae, Asif Ahmed, 2009, Bioorganic & medicinal chemistry.

Synthesis and biological evaluation of arylsulfonylpiperazine derivatives as 5-HT6 receptor ligands

Y. Cho, H. Rhim, H. Koh, 2007 .

Classification of Piperazinylalkylisoxazole Library by Recursive Partitioning

Y. Cho, H. Koh, A. Pae, 2008 .

Synthesis and Biological Evaluation of Isoxazoline and Isoxazole Derivatives as 5-HT2A and 5-HT2C Receptor Ligands

Y. Cho, H. Koh, A. Pae, 2009 .