Bochun Hu

发表

Enantioconvergent hydrolysis of racemic epoxides at elevated concentrations in Tween-20/phosphate buffer by the corresponding epoxide hydrolases

Wenqian Lin, Bochun Hu, Xiuxiu Zhu, 2022, Process Biochemistry.

Near-perfect kinetic resolution of racemic p-chlorostyrene oxide by SlEH1, a novel epoxide hydrolase from Solanum lycopersicum with extremely high enantioselectivity.

Minchen Wu, D. Hu, Bochun Hu, 2019, International journal of biological macromolecules.

Nearly perfect kinetic resolution of racemic o-nitrostyrene oxide by AuEH2, a microsomal epoxide hydrolase from Aspergillus usamii, with high enantio- and regio-selectivity.

D. Zhang, Minchen Wu, D. Hu, 2020, International journal of biological macromolecules.

Characterization of a robust glucose 1-dehydrogenase, SyGDH, and its application in NADPH regeneration for the asymmetric reduction of haloketone by a carbonyl reductase in organic solvent/buffer system

Jianfang Li, Minchen Wu, D. Hu, 2020 .

Manipulating regioselectivity of an epoxide hydrolase for single enzymatic synthesis of (R)-1,2-diols from racemic epoxides.

Minchen Wu, F. Xue, D. Hu, 2020, Chemical communications.

Near-perfect kinetic resolution of o-methylphenyl glycidyl ether by RpEH, a novel epoxide hydrolase from Rhodotorula paludigena JNU001 with high stereoselectivity

Minchen Wu, D. Hu, Bochun Hu, 2020, Applied Microbiology and Biotechnology.

Structure-guided improvement in the enantioselectivity of an Aspergillus usamii epoxide hydrolase for the gram-scale kinetic resolution of ortho-trifluoromethyl styrene oxide.

D. Zhang, Minchen Wu, D. Hu, 2021, Enzyme and microbial technology.

Stereoselective ring-opening of styrene oxide at elevated concentration by Phaseolus vulgaris epoxide hydrolase, PvEH2, in the organic/aqueous biphasic system

Minchen Wu, D. Hu, Bochun Hu, 2019, Catalysis Communications.

Engineering the regiocomplementarity of an epoxide hydrolase from Rhodotorula paludigena by means of computer-aided design for the scale-up enantioconvergent hydrolysis of racemic m-nitrostyrene oxide

Dong Zhang, Min Wu, Bochun Hu, 2022, Biochemical Engineering Journal.

Manipulating the regioselectivity of a Solanum lycopersicum epoxide hydrolase for the enantioconvergent synthesis of enantiopure alkane- and alkene-1,2-diols

D. Zhang, Minchen Wu, D. Hu, 2020 .

Decoquinate derivatives: A new class of potent antischistosomal agents against Schistosoma japonicum

S. Lijun, W. Fan, Bochun Hu, 2017 .

Greatly enhancing the enantioselectivity of PvEH2, a Phaseolus vulgaris epoxide hydrolase, towards racemic 1,2-epoxyhexane via replacing its partial cap-loop.

Minchen Wu, D. Hu, Bochun Hu, 2020, International journal of biological macromolecules.

Substantially improving the enantioconvergence of PvEH1, a Phaseolus vulgaris epoxide hydrolase, towards m-chlorostyrene oxide by laboratory evolution

D. Hu, Bochun Hu, Chuang Li, 2019, Microbial Cell Factories.

Engineering a BsBDHA substrate-binding pocket entrance for the improvement in catalytic performance toward (R)-phenyl-1,2-ethanediol based on the computer-aided design

Yu Hu, Bochun Hu, Xinchao Yuan, 2023, Biochemical engineering journal.

Improvement in the activity and enantioconvergency of PvEH3, an epoxide hydrolase from Phaseolus vulgaris, for p-chlorostyrene oxide by site-saturation mutagenesis

Jianfang Li, Bochun Hu, Chuang Li, 2018, Catalysis Communications.

Multiple site-directed mutagenesis of a Phaseolus vulgaris epoxide hydrolase to improve its catalytic performance towards p-chlorostyrene oxide based on the computer-aided re-design.

D. Hu, Bochun Hu, Chuang Li, 2019, International Journal of Biological Macromolecules.

Structure-Guided Regulation in the Enantioselectivity of an Epoxide Hydrolase to Produce Enantiomeric Monosubstituted Epoxides and Vicinal Diols via Kinetic Resolution.

Dong Zhang, D. Hu, Bochun Hu, 2022, Organic letters.