F. Bortolotti

发表

Pullulan-cyclodextrin microspheres. A chromatographic approach for the evaluation of the drug-cyclodextrin interactions and the determination of the drug release profiles.

P. Ascenzi, R. Cortesi, E. Menegatti, 2003, Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.

Amphiphilic association systems for Amphotericin B delivery.

R. Cortesi, E. Esposito, E. Menegatti, 2003, International journal of pharmaceutics.

Research Article Caffeine intake induces an alteration in human neutrophil A 2A adenosine receptors

K. Varani, F. Portaluppi, A. Dalpiaz, 2005 .

Steady-state and pre-steady-state kinetics of the trypsin-catalysed hydrolysis of alpha-CBZ-L-lysine-p-nitrophenyl ester.

E. Antonini, E. Menegatti, F. Bortolotti, 1981, Biochimica et biophysica acta.

Cellulose acetate butyrate-pH/thermosensitive polymer microcapsules containing aminated poly(vinyl alcohol) microspheres for oral administration of DNA.

P. Ascenzi, R. Cortesi, E. Menegatti, 2007, European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V.

Preparation and characterisation of poly(vinyl alcohol)/cyclodextrin microspheres as matrix for inclusion and separation of drugs.

P. Ascenzi, R. Cortesi, E. Menegatti, 2004, International journal of pharmaceutics.

Multicomponent antibiotic substances produced by fermentation: implications for regulatory authorities, critically ill patients and generics.

P. Colombo, G. Colombo, A. Brink, 2014, International journal of antimicrobial agents.

Purification, inhibitory properties, amino acid sequence and identification of the reactive site of a new serine proteinase inhibitor from oil‐rape (itBrassica napus) seed

P. Ascenzi, E. Menegatti, F. Ceciliani, 1994, FEBS letters.

Development and characterization of biodegradable nanospheres as delivery systems of anti-ischemic adenosine derivatives.

F. Forni, M. Vandelli, E. Leo, 2005, Biomaterials.

Vitamin C and 6-amino-vitamin C conjugates of diclofenac: synthesis and evaluation.

A. Dalpiaz, S. Manfredini, C. Biondi, 2005, International journal of pharmaceutics.

Ascorbic and 6-Br-ascorbic acid conjugates as a tool to increase the therapeutic effects of potentially central active drugs.

L. Ferraro, S. Tanganelli, P. Prasad, 2005, European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences.

Design, synthesis and in vitro evaluation on HRPE cells of ascorbic and 6-bromoascorbic acid conjugates with neuroactive molecules.

P. Prasad, A. Dalpiaz, S. Manfredini, 2004, Bioorganic & medicinal chemistry.

Transporter-mediated effects of diclofenamic acid and its ascorbyl pro-drug in the in vivo neurotropic activity of ascorbyl nipecotic acid conjugate.

L. Ferraro, S. Tanganelli, P. Prasad, 2004, Journal of pharmaceutical sciences.

A novel multicompartimental system based on aminated poly(vinyl alcohol) microspheres/succinoylated pullulan microspheres for oral delivery of anionic drugs.

R. Cortesi, E. Menegatti, G. Fundueanu, 2007, International journal of pharmaceutics.

Poly[(N-isopropylacrylamide-co-acrylamide-co-(hydroxyethylmethacrylate))] thermoresponsive microspheres: An accurate method based on solute exclusion technique to determine the volume phase transition temperature

P. Ascenzi, R. Cortesi, E. Menegatti, 2007 .

Isolation and characterization of a new form of the porcine pancreatic secretory trypsin inhibitor. Biochemical studies and high-resolution 1H-NMR.

E. Menegatti, A. D. Marco, L. Minchiotti, 1982, Biochimica et biophysica acta.

Conjugation of aspirin with vitamin C: uptake and stability studies

A. Dalpiaz, S. Manfredini, C. Biondi, 2009 .

Reversed-phase HPLC study on the in vitro enzymic degradation of dermorphin

S. Salvadori, S. Scalia, M. Marastoni, 1986, Peptides.

Purification, inhibitory properties and amino acid sequence of a new serine proteinase inhibitor from white mustard (Sinapis alba L.) seed

M. Bolognesi, P. Ascenzi, E. Menegatti, 1992, FEBS letters.

Opportunity and challenges of nasal powders: Drug formulation and delivery

P. Russo, G. Colombo, F. Sonvico, 2017, European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences.

Binding of native and [homoserine lactone‐52]‐52,53‐seco‐bovine basic pancreatic trypsin inhibitor (kunitz inhibitor) to porcine pancreatic β‐kallikrein‐B and bovine α‐chymtorpsin: Thermodynaic study

M. Bolognesi, P. Ascenzi, D. Barra, 1994 .

Therapeutic Paint of Cidofovir/Sucralfate Gel Combination Topically Administered by Spraying for Treatment of orf virus Infections

P. Colombo, G. Colombo, F. Sonvico, 2009, AAPS Journal.

In vitro permeation of desmopressin across rabbit nasal mucosa from liquid nasal sprays: the enhancing effect of potassium sorbate.

P. Russo, G. Colombo, F. Sonvico, 2009, European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences.

Enzymatic Synthesis of 2′-O-acyl Prodrugs of 1-(β-D-arabinofuranosyl)-5(E)-(2-bromovinyl)uracil and of 2′-O-acyl-araU, -araC and -araA

S. Manfredini, S. Vertuani, F. Bortolotti, 1998, Antiviral chemistry & chemotherapy.

HIV protease inhibitors: synthesis and activity of N-aryl-N'-hydroxyalkyl hydrazide pseudopeptides.

C. Trapella, M. Marastoni, A. Baldisserotto, 2005, European journal of medicinal chemistry.

Preparation and characterization of starch/cyclodextrin bioadhesive microspheres as platform for nasal administration of Gabexate Mesylate (Foy) in allergic rhinitis treatment.

P. Ascenzi, R. Cortesi, E. Menegatti, 2004, Biomaterials.

Brain uptake of an anti-ischemic agent by nasal administration of microparticles.

L. Ferraro, S. Tanganelli, P. Russo, 2008, Journal of pharmaceutical sciences.

Cationic liposomes as potential carriers for ocular administration of peptides with anti-herpetic activity.

R. Manservigi, R. Cortesi, E. Esposito, 2006, International journal of pharmaceutics.

Catalytic properties of serine proteases. 2. Comparison between human urinary kallikrein and human urokinase, bovine beta-trypsin, bovine thrombin, and bovine alpha-chymotrypsin.

E. Antonini, E. Menegatti, F. Bortolotti, 1982, Biochemistry.

In vivo nose-to-brain delivery of the hydrophilic antiviral ribavirin by microparticle agglomerates

E. Zironi, L. Calzà, G. Colombo, 2018, Drug delivery.

Anti-inflammatory flurbiprofen nasal powders for nose-to-brain delivery in Alzheimer’s disease

P. Russo, P. Colombo, G. Colombo, 2019, Journal of drug targeting.

Characterization of low-molecular-mass trypsin isoinhibitors from oil-rape (Brassica napus var. oleifera) seed.

S. Pascarella, P. Ascenzi, P. Pucci, 1999, European journal of biochemistry.

Complex product composition generates risks for generic substitution also with dosage forms for intravenous administration.

M. Mor, P. Colombo, G. Colombo, 2013, International journal of pharmaceutics.

Highly selective fluorescent analogue of the potent delta-opioid receptor antagonist Dmt-Tic.

S. Salvadori, G. Balboni, R. Argazzi, 2004, Journal of medicinal chemistry.

Catalytic properties of human urinary kallikrein 1

P. Ascenzi, E. Antonini, E. Menegatti, 1982 .

Diffusion of preservatives from topical dosage forms: a comparative study.

C. Nastruzzi, R. Cortesi, E. Esposito, 2003, Journal of cosmetic science.

Antidiuretic effect of desmopressin chimera agglomerates by nasal administration in rats.

L. Ferraro, P. Russo, P. Colombo, 2013, International journal of pharmaceutics.

Gabexate mesylate inhibition of serine proteases: thermodynamic and computer-graphics analysis.

M. Bolognesi, E. Menegatti, S. Scalia, 1986, Journal of pharmaceutical sciences.

Molecular mechanism involved in the transport of a prodrug dopamine glycosyl conjugate.

P. Prasad, A. Dalpiaz, C. Biondi, 2007, International journal of pharmaceutics.

Synthesis and activity of N-benzyl pseudopeptides HIV protease inhibitors.

M. Marastoni, R. Tomatis, M. Bazzaro, 2003, Bioorganic & medicinal chemistry.

HIV-1 protease inhibitors containing a novel C2 symmetrical hydroxyalkylgem-diamino core structure.

S. Salvadori, M. Marastoni, R. Tomatis, 2009, The journal of peptide research : official journal of the American Peptide Society.

Nanoparticle formulation may affect the stabilization of an antiischemic prodrug.

G. Tosi, E. Leo, C. Contado, 2006, International journal of pharmaceutics.

Preparation and characterisation of thermoresponsive poly[(N-isopropylacrylamide-co-acrylamide-co-(hydroxyethyl acrylate)] microspheres as a matrix for the pulsed release of drugs.

P. Ascenzi, R. Cortesi, E. Menegatti, 2005, Macromolecular bioscience.

Caffeine intake induces an alteration in human neutrophil A2A adenosine receptors

K. Varani, F. Portaluppi, A. Dalpiaz, 2005, Cellular and Molecular Life Sciences CMLS.

A novel conjugated agent between dopamine and an A2A adenosine receptor antagonist as a potential anti-Parkinson multitarget approach.

S. Federico, G. Spalluto, B. Cacciari, 2012, Molecular pharmaceutics.

Controlled proteolysis of mouse epidermal growth factor. An RP-HPLC and 1H-n.m.r. study.

E. Menegatti, S. Scalia, F. Bortolotti, 2009, International journal of peptide and protein research.

HIV-1 protease inhibitors containing an N-hydroxyamino acid core structure.

S. Salvadori, M. Marastoni, R. Tomatis, 2001, Bioorganic & medicinal chemistry.

Synthesis and Study of 5′-Ester Prodrugs of N6-Cyclopentyladenosine, a Selective A1 Receptor Agonist

E. Menegatti, A. Dalpiaz, S. Manfredini, 2001, Pharmaceutical Research.

Orphan Designation and Cisplatin/Hyaluronan Complex in an Intracavitary Film for Malignant Mesothelioma

P. Colombo, G. Colombo, F. Sonvico, 2021, Pharmaceutics.

Synthesis and Activity of New Acylated Diaminohydroxyalkanes as Human Immunodeficiency Virus Protease Inhibitors

M. Marastoni, R. Tomatis, M. Bazzaro, 2000, Arzneimittelforschung.

Flurbiprofen Sodium Microparticles and Soft Pellets for Nose-to-Brain Delivery: Serum and Brain Levels in Rats after Nasal Insufflation.

P. Russo, N. Kostomitsopoulos, P. Colombo, 2021, International journal of pharmaceutics.

Production and characterization of biodegradable microparticles for the controlled delivery of proteinase inhibitors

C. Nastruzzi, R. Cortesi, E. Esposito, 1996 .