Hisanaka Ito

发表

Asymmetric Aldol Reaction via a Dinuclear Zinc Catalyst: α-Hydroxyketones as Donors

B. Trost, E. Silcoff, Hisanaka Ito, 2001 .

A Direct Catalytic Enantioselective Aldol Reaction via a Novel Catalyst Design

Hisanaka Ito, B. M. T. and, 2000 .

Asymmetric Synthesis and Structure Revision of Guignardone H and I: Development of a Chiral 1,3-Diketone Possessing C2 Symmetry.

H. Abe, Yuichiro Kawamoto, Toyoharu Kobayashi, 2019, Organic letters.

Asymmetric total synthesis of pleurospiroketals A and B.

H. Abe, Toyoharu Kobayashi, Hisanaka Ito, 2018, Chemical communications.

Pathological Role of Pin1 in the Development of DSS-Induced Colitis

T. Asano, Hiraku Ono, H. Sakoda, 2021, Cells.

Concise total synthesis of spirocurcasone.

H. Abe, Toyoharu Kobayashi, Hisanaka Ito, 2013, Organic letters.

Prolyl isomerase Pin1 plays an essential role in SARS-CoV-2 proliferation, indicating its possibility as a novel therapeutic target

T. Asano, Y. Nakatsu, Takeshi Yamamotoya, 2021, Scientific Reports.

Roles of peptidyl prolyl isomerase Pin1 in viral propagation

T. Asano, Y. Nakatsu, Takeshi Yamamotoya, 2022, Frontiers in Cell and Developmental Biology.

(S,S)‐2,6‐Bis((2‐(hydroxydiphenylmethyl)‐1‐pyrrolidinyl)methyl)‐4‐methylphenol

Hisanaka Ito, 2008 .

Total synthesis of the tricyclic humulanolide wilfolide B

H. Abe, Toyoharu Kobayashi, Hisanaka Ito, 2019, Tetrahedron Letters.

Stereocontrolled asymmetric synthesis of mollebenzylanols A and B using Claisen rearrangements

Yuichiro Kawamoto, Toyoharu Kobayashi, Hisanaka Ito, 2021 .

Enantioselective Total Synthesis of Mollebenzylanol A.

Yuichiro Kawamoto, Toyoharu Kobayashi, Hisanaka Ito, 2020, Organic letters.

[Development of novel carbon-carbon bond forming reactions using zirconocene complex].

Hisanaka Ito, 2003, Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan.

Total Synthesis of Catunaregin and Preliminary Evaluation of Its Antitumor Activity

H. Abe, Toyoharu Kobayashi, Y. Mimaki, 2018 .

Convenient preparation of synthetically useful chiral quaternary carbon-containing bicyclic compounds with organocatalysts

Yuichiro Kawamoto, Toyoharu Kobayashi, Hisanaka Ito, 2021, Tetrahedron Letters.

Enantioselective Total Synthesis of Chondrosterins I and J by Catalytic Asymmetric Intramolecular Aldol Reaction Using Chiral Diamine Catalyst

Yuichiro Kawamoto, Toyoharu Kobayashi, Hisanaka Ito, 2020 .

Total synthesis of (±)-chondrosterin I using a desymmetric aldol reaction.

Yuichiro Kawamoto, Toyoharu Kobayashi, Hisanaka Ito, 2018, Organic & biomolecular chemistry.

Asymmetric Claisen rearrangement

Hisanaka Ito, T. Taguchi, 1999 .

Zirconium-Mediated, Highly Diastereoselective Ring Contraction of Vinylmorpholine Derivatives from .alpha.-Amino Acids: An Application to the Synthesis of (-)-Macronecine

M. Shiro, Y. Hanzawa, Hisanaka Ito, 1994 .

Generation of allylic and related organozirconiums through a highly effective zirconium—β-alkoxide elimination reaction

Y. Hanzawa, Hisanaka Ito, Takanori Nakamura, 1995 .

Practical zirconium-mediated deprotective method of allyl groups

Y. Hanzawa, Hisanaka Ito, T. Taguchi, 1993 .

Preparation and reactions of allenic zirconium species from propargylic ether derivatives

Y. Hanzawa, Hisanaka Ito, Takanori Nakamura, 1992 .

Preparation and regio- and diastereoselective reactions of allylic zirconium reagents from allylic ether derivatives

Y. Hanzawa, Hisanaka Ito, T. Taguchi, 1992 .

Construction of Optically Active Spiroketal by Direct Aldol Reaction

K. Iguchi, Hisanaka Ito, Chie Kawabe, 2006 .

Concise asymmetric total synthesis of catunaregin

H. Abe, Toyoharu Kobayashi, Hisanaka Ito, 2016 .

A Direct Catalytic Enantioselective Aldol Reaction via a Novel Catalyst Design.

B. Trost, Hisanaka Ito, 2001 .

Synthesis of 2-fluoro analog of 6-aminonorbornane-2,6-dicarboxylic acid: A conformationally rigid glutamic acid derivative

A. Saito, Hisanaka Ito, T. Taguchi, 1999 .

Enantioselective aromatic Claisen rearrangement

Hisanaka Ito, T. Taguchi, Azusa Sato, 1997 .

Zirconium-mediated ring contraction : an efficient synthesis of enantiomerically pure key intermediate of carbocyclic oxetanocin

Y. Hanzawa, Hisanaka Ito, T. Taguchi, 1993 .

Catalytic enantioselective [2+2]-cycloaddition reaction of 2-methoxycarbonyl-2-cyclopenten-1-one by chiral copper catalyst

K. Iguchi, Hisanaka Ito, Mineki Hasegawa, 2006 .

A practical preparation of 2-hydroxymethyl-2-cyclopenten-1-one by morita-baylis-hillman reaction

K. Iguchi, Hisanaka Ito, Yosuke Takenaka, 2005 .

Concise total synthesis of albaflavenone utilizing sequential intramolecular aldol condensation: determination of absolute configuration.

H. Abe, Toyoharu Kobayashi, Hisanaka Ito, 2014, Organic letters.

Enantioselective synthesis of curacin A. 1. Construction of C1–C7, C8–17, and C18–C22 segments

Susumu Kobayashi, N. Imai, Hisanaka Ito, 1996 .

Enantioselective synthesis of curacin A. 2. Total synthesis of curacin A by condensation of C1–C7, C8–C17, and C18–C22 segments

K. Takao, Susumu Kobayashi, N. Imai, 1996 .

1,4-Addition reaction of γ, γ-dialkoxyallylic zirconium species as agem-dialkoxycyclopropyl anion equivalent

Hisanaka Ito, T. Taguchi, Azusa Sato, 1999 .

Synthetic study of yonarolide: stereoselective construction of the tricyclic core

K. Iguchi, H. Abe, Hisanaka Ito, 2011 .

Lewis acid promoted reactions of γ,γ-dialkoxyallylic zirconium species with various carbonyl compounds

Hisanaka Ito, T. Taguchi, Azusa Sato, 2005 .

A stereoselective preparation of 1-fluorocyclopropane-1-carboxylate derivatives through radical addition of fluoroiodoacetate to alkenes followed by intramolecular substitution reaction

A. Saito, Hisanaka Ito, T. Taguchi, 2001 .

Enantioselective total synthesis of (+)-tricycloclavulone.

K. Iguchi, Hisanaka Ito, Mineki Hasegawa, 2004, Journal of the American Chemical Society.

Zirconium-mediated intramolecular ester transfer reaction: synthesis of alpha-substituted gamma-aminobutyric acid (GABA) derivatives.

Hisanaka Ito, T. Taguchi, Katsunori Omodera, 2002, Organic letters.

Enantioselective total synthesis of both diastereomers of preclavulone-A methyl ester

K. Iguchi, Masami Konishi, Hisanaka Ito, 2006 .

Enantioselective Total Synthesis of Diocollettines A.

Yuichiro Kawamoto, Toyoharu Kobayashi, Hisanaka Ito, 2019, Organic letters.

Enantioselective Claisen rearrangement of difluorovinyl allyl ethers

Hisanaka Ito, T. Taguchi, Azusa Sato, 1998 .

Asymmetric Diels–Alder reactions of 2-fluoroacrylic acid derivatives. Part 2: A remarkable effect of fluorine substituent on the diastereoselectivity

A. Saito, Hisanaka Ito, T. Taguchi, 1998 .

Enantioselective formal synthesis of (+)-precapnelladiene by chiral copper-catalyzed asymmetric [2+2]-cycloaddition reaction

K. Iguchi, Hisanaka Ito, Yosuke Takenaka, 2007 .

Copper-catalyzed addition reaction of γ,γ-dialkoxyallylic zirconium species with imines

Hisanaka Ito, T. Taguchi, Azusa Sato, 2005 .

Zirconium-mediated diastereoselective coupling reactions of chiral aldimine: Remarkable temperature-dependence of chiral induction

Y. Hanzawa, Hisanaka Ito, T. Taguchi, 1992 .

Cu(I)-assisted carboncarbon bond forming reactions of γ,γ-dialkoxyallylic zirconium species: a new versatile homoenolate equivalent of propionate

Hisanaka Ito, Yusuke Yamaguchi, T. Taguchi, 2000 .

Highly stereocontrolled total synthesis of secodolastane diterpenoid isolinearol.

Yuichiro Kawamoto, Toyoharu Kobayashi, Hisanaka Ito, 2020, Organic & biomolecular chemistry.

Asymmetric Claisen rearrangement

Hisanaka Ito, T. Taguchi, 1999 .

Intramolecular Diels-Alder reactions of ester-tethered 1,7,9-decatrienoates: bis[chloro(methyl)aluminum]trifluoromethanesulfonamide as a catalyst.

A. Saito, Hisanaka Ito, T. Taguchi, 2002, Organic letters.

The Total Synthesis of (±)-Naupliolide: A Tetracyclic Sesquiterpene Lactone.

Kérya Long, H. Abe, Toyoharu Kobayashi, 2016, Angewandte Chemie.

Indium chloride mediated chlorolactonization: construction of chlorinated lactone fragments

H. Abe, Toyoharu Kobayashi, Hisanaka Ito, 2013 .

Preparation and reactions of γ,γ-dialkoxyallylic zirconium species: α,β-Unsaturated acyl anion equivalent

Hisanaka Ito, T. Taguchi, 1997 .

Zirconium-mediated, highly diastereoselective ring contraction of carbohydrate derivatives : synthesis of highly functionalized, enantiomerically pure carbocycles

Y. Hanzawa, Hisanaka Ito, T. Taguchi, 1993 .

Zirconium‐Mediated, Highly Diastereoselective Ring Contraction of Vinylmorpholine Derivatives from α‐Amino Acids: An Application to the Synthesis of (‐)‐Macronecine.

M. Shiro, Y. Hanzawa, Hisanaka Ito, 1994 .

Preparation and reactions of alkoxy allylic zirconium reagents derived from acetals of α,β-unsaturated aldehydes: Remarkable substituent effects on regioselectivity

Y. Hanzawa, Hisanaka Ito, T. Taguchi, 1992 .

Formation of Carbon-Carbon Bonds using Zirconocene-Butene Complex (”Cp2Zr”) as a Synthetic Tool

Y. Hanzawa, Hisanaka Ito, T. Taguchi, 1995 .

Quinolinecarboxylic acid based fluorescent molecules: ratiometric response to Zn2+

K. Iguchi, Y. Kudo, Hisanaka Ito, 2009 .

A synthetic study of briarane-type marine diterpenoid, pachyclavulide B

K. Iguchi, Hisanaka Ito, Junya Iwasaki, 2006 .

Total Synthesis of Applanatumol B.

Yuichiro Kawamoto, Toyoharu Kobayashi, Hisanaka Ito, 2019, Organic letters.

Asymmetric syntheses of ent-callilongisins B and C

Yuichiro Kawamoto, Toyoharu Kobayashi, Hisanaka Ito, 2022, Tetrahedron.

Total Synthesis of ent-Callilongisin B.

Yuichiro Kawamoto, Toyoharu Kobayashi, Hisanaka Ito, 2021, Organic letters.

Construction of nitrogen-heterocyclic compounds through zirconium mediated intramolecular alkene-carbonyl coupling reaction of N-(o-alkenylaryl)carbamate derivatives

Hisanaka Ito, T. Taguchi, Maiko Ito, 2004 .

Total Synthesis of Paralemnolide A.

H. Abe, Toyoharu Kobayashi, Yuta Ogura, 2017, Organic letters.

Stereoselective total synthesis of preclavulone-A methyl ester and its diastereomer

K. Iguchi, Masami Konishi, Hisanaka Ito, 2004 .

Synthesis of Fluorescence Pyriproxyfen Analogues as Juvenile Hormone Agonists

H. Abe, S. Tokishita, T. Ohta, 2011 .

Sequential condensation-6π-electrocyclization reaction of a chiral 1,3-Diketone possessing C2 symmetry

Yuichiro Kawamoto, Toyoharu Kobayashi, Hisanaka Ito, 2020 .

Total synthesis of pleurolactone

H. Abe, Toyoharu Kobayashi, Hisanaka Ito, 2017 .

Diastereoselective Total Synthesis of (±)‐Toxicodenane A

H. Abe, Toyoharu Kobayashi, Hisanaka Ito, 2017 .

Palladium(0)-mediated intramolecular lactonization of allylic alcohol derivatives; unusual substituent effect of the trifluoromethyl group on δ-lactone formation

Y. Hanzawa, Hisanaka Ito, T. Taguchi, 1990 .

Directed synthesis of 2-spiroindolines from indole derivatives by formic acid-induced N-acyliminium ion-conjugated diene spirocyclization

H. Abe, T. Katoh, Toyoharu Kobayashi, 2015 .

Expression of kinase-deficient MEK2 ameliorates Pelizaeus-Merzbacher disease phenotypes in mice.

K. Mizoguchi, K. Ohbuchi, Y. Miyamoto, 2020, Biochemical and biophysical research communications.

Development of Pin1 inhibitors and their potential as therapeutic agents.

T. Asano, K. Ueda, Hiraku Ono, 2020, Current medicinal chemistry.

Marine diterpenoids with a briarane skeleton from the Okinawan soft coral Pachyclavularia violacea.

K. Iguchi, T. Yamori, Hisanaka Ito, 2007, Chemical & pharmaceutical bulletin.

Total synthesis of applanatumols X and Y

Yuichiro Kawamoto, Toyoharu Kobayashi, Hisanaka Ito, 2020 .

Asymmetric Diels–Alder reactions of 2-fluoroacrylic acid derivatives. Part 1: The construction of fluorine substituted chiral tertiary carbon

A. Saito, Hisanaka Ito, T. Taguchi, 1998 .

Briarane-type diterpenoids from the Okinawan soft coral Pachyclavularia violacea.

K. Iguchi, Hisanaka Ito, Yuki Sato, 2006, Journal of natural products.

Synthetic study of marine diterpenoid aberrarone: stereocontrolled construction of tetracyclic framework

H. Abe, Toyoharu Kobayashi, Hisanaka Ito, 2015 .

Asymmetric total synthesis of stachyodins A and B

Yuichiro Kawamoto, Toyoharu Kobayashi, Hisanaka Ito, 2021, Tetrahedron.

Total Synthesis of Nesteretal A.

Yuichiro Kawamoto, Toyoharu Kobayashi, Hisanaka Ito, 2021, Organic letters.

Structurally simplified zaragozic acid (squalestatin): Stereoselective preparation of a 3,4-unsubstituted derivative

K. Takao, Susumu Kobayashi, Hisanaka Ito, 1997 .

Direct asymmetric aldol reactions of acetone using bimetallic zinc catalysts.

B. Trost, E. Silcoff, Hisanaka Ito, 2001, Organic letters.

Synthetic Study of Presilphiperfolan-8-ol: Construction of the Tricyclo[5.3.1.04,11]undecane Framework Utilizing Intramolecular Aldol Condensation and McMurry Coupling

H. Abe, Toyoharu Kobayashi, Hisanaka Ito, 2013 .

Catalytic enantioselective [2+2]-cycloaddition reaction of 2-methoxycarbonyl-2-cyclopenten-1-one by chiral copper catalyst

K. Iguchi, Hisanaka Ito, Mineki Hasegawa, 2006 .

Stereoselective synthesis of a highly oxygenated decahydrocyclopenta[g]chromene derivative: the common tricyclic framework of leucosceptrine and leucosesterterpenone.

H. Abe, Toyoharu Kobayashi, Hisanaka Ito, 2015, Chemical communications.