Frank Wu

Discovery of an Orally Available Diazabicyclooctane Inhibitor (ETX0282) of Class A, C, and D Serine β-Lactamases

S. McLeod, R. Tommasi, M. Sacco, 2020, Journal of medicinal chemistry.

Hit to lead account of the discovery of bisbenzamide and related ureidobenzamide inhibitors of Rho kinase.

C. Cywin, E. Hickey, M. Kashem, 2010, Journal of medicinal chemistry.

Substituted 2H-isoquinolin-1-one as potent Rho-Kinase inhibitors. Part 1: Hit-to-lead account.

C. Cywin, E. Hickey, M. Kashem, 2010, Bioorganic & medicinal chemistry letters.

N-Arylsulfonyl-α-amino carboxamides are potent and selective inhibitors of the chemokine receptor CCR10 that show efficacy in the murine DNFB model of contact hypersensitivity.

D. Jeanfavre, N. Moss, Jiang-Ping Wu, 2016, Bioorganic & medicinal chemistry letters.

Discovery of Imigliptin, a Novel Selective DPP-4 Inhibitor for the Treatment of Type 2 Diabetes.

Jun Xu, H. Ge, P. Peng, 2014, ACS medicinal chemistry letters.

Simultaneous determination of imigliptin and its three metabolites in human plasma and urine by liquid chromatography coupled to tandem mass spectrometry.

Dongyang Liu, Hanlin Song, Yang Liu, 2015, Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.

Substituted 2H-isoquinolin-1-ones as potent Rho-kinase inhibitors: part 2, optimization for blood pressure reduction in spontaneously hypertensive rats.

Xiang Li, C. Cywin, E. Hickey, 2010, Bioorganic & medicinal chemistry letters.

Quantitative prediction of human pharmacokinetics and pharmacodynamics of imigliptin, a novel DPP-4 inhibitor, using allometric scaling, IVIVE and PK/PD modeling methods.

Dongyang Liu, Yang Liu, Ji Jiang, 2016, European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences.

SAR and Structural Analysis of Siderophore-Conjugated Monocarbam Inhibitors of Pseudomonas aeruginosa PBP3.

A. Ferguson, Kerry E. Murphy-Benenato, Ning Gao, 2015, ACS medicinal chemistry letters.

In vitro and in vivo evaluation of O-alkyl derivatives of tramadol.

M. Currie, C. Senanayake, M. Hewitt, 2008, Bioorganic & medicinal chemistry letters.

Simultaneous determination of imigliptin and its three metabolites in human plasma and urine by liquid chromatography coupled to tandem mass spectrometry.

Dongyang Liu, Hanlin Song, Yang Liu, 2015, Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.