C. R. de los Santos

发表

NMR structural studies of intramolecular (Y+)n.(R+)n(Y-)nDNA triplexes in solution: imino and amino proton and nitrogen markers of G.TA base triple formation.

D. Patel, I. Radhakrishnan, D. Live, 1991, Biochemistry.

Nuclear magnetic resonance structural studies of intramolecular purine.purine.pyrimidine DNA triplexes in solution. Base triple pairing alignments and strand direction.

D. Patel, I. Radhakrishnan, C. R. de los Santos, 1991, Journal of molecular biology.

Structure and stability of duplex DNA containing (5'S)-5',8-cyclo-2'-deoxyadenosine: an oxidatively generated lesion repaired by NER.

M. Lukin, C. R. de los Santos, Tatiana Zaliznyak, 2012, Chemical research in toxicology.

A dynamic checkpoint in oxidative lesion discrimination by formamidopyrimidine–DNA glycosylase

C. Simmerling, Christina Bergonzo, A. Grollman, 2015, Nucleic acids research.

Putrescine distribution in Escherichia coli studied in vivo by 13C nuclear magnetic resonance.

I. D. Algranati, B. Frydman, R. Frydman, 1984, Biochimica et biophysica acta.

NMR Characterization of a DNA Duplex Containing the Major Acrolein-derived Deoxyguanosine Adduct γ-OH-1,-N 2-Propano-2′-deoxyguanosine*

F. Johnson, C. R. de los Santos, T. Zaliznyak, 2001, The Journal of Biological Chemistry.

Carbon-13 nuclear magnetic resonance analysis of [1-13C]glucose metabolism in Crithidia fasciculata. Evidence of CO2 fixation by phosphoenolpyruvate carboxykinase.

J. Cazzulo, J. Cannata, B. Frydman, 1985, European journal of biochemistry.

NMR studies of the exocyclic 1,N6-ethenodeoxyadenosine adduct (epsilon dA) opposite deoxyguanosine in a DNA duplex. Epsilon dA(syn).dG(anti) pairing at the lesion site.

D. Patel, K. Yarema, J. Essigmann, 1991, Biochemistry.

Dynamic behavior of DNA base pairs containing 8-oxoguanine.

V. Hornak, C. Simmerling, A. Grollman, 2005, Journal of the American Chemical Society.

Multinuclear nuclear magnetic resonance studies of Na cation-stabilized complex formed by d(G-G-T-T-T-T-C-G-G) in solution. Implications for G-tetrad structures.

D. Patel, Y. Wang, D. Live, 1991, Journal of molecular biology.

An Improved Reaction Coordinate for Nucleic Acid Base Flipping Studies.

C. Simmerling, Christina Bergonzo, A. Grollman, 2009, Journal of chemical theory and computation.

Energetic preference of 8-oxoG eversion pathways in a DNA glycosylase.

C. Simmerling, Christina Bergonzo, A. Grollman, 2011, Journal of the American Chemical Society.

Computational analysis of the mode of binding of 8-oxoguanine to formamidopyrimidine-DNA glycosylase.

V. Hornak, C. Simmerling, A. Grollman, 2006, Biochemistry.

Integrity of duplex structures without hydrogen bonding: DNA with pyrene paired at abasic sites.

E. Kool, S. Smirnov, C. R. de los Santos, 2002, Nucleic acids research.

NMR studies of DNA (R+)n.(Y-)n.(Y+)n triple helices in solution: imino and amino proton markers of T.A.T and C.G.C+ base-triple formation.

D. Patel, M. Rosen, C. R. de los Santos, 1989, Biochemistry.

Solution structure of DNA containing α-OH-PdG: the mutagenic adduct produced by acrolein

F. Johnson, S. Attaluri, C. R. de los Santos, 2009, Nucleic acids research.

Spectroscopic evidence for a porphobilinogen deaminase-tetrapyrrole complex that is an intermediate in the biosynthesis of uroporphyrinogen III.

B. Frydman, A. Sburlati, R. Frydman, 1988, Biochemistry.

Solution conformation of the (+)-cis-anti-[BP]dG adduct in a DNA duplex: intercalation of the covalently attached benzo[a]pyrenyl ring into the helix and displacement of the modified deoxyguanosine.

D. Patel, B. Hingerty, S. Broyde, 1993, Biochemistry.

Influence of benzo[a]pyrene diol epoxide chirality on solution conformations of DNA covalent adducts: the (-)-trans-anti-[BP]G.C adduct structure and comparison with the (+)-trans-anti-[BP]G.C enantiomer.

D. Patel, B. Hingerty, S. Broyde, 1992, Biochemistry.

Solution conformation of the major adduct between the carcinogen (+)-anti-benzo[a]pyrene diol epoxide and DNA.

D. Patel, B. Hingerty, S. Broyde, 1992, Proceedings of the National Academy of Sciences of the United States of America.

Solution structure of duplex DNA containing a β-carba-Fapy-dG lesion.

F. Johnson, M. Lukin, S. Attaluri, 2013, Chemical research in toxicology.

Novel post-synthetic generation, isomeric resolution, and characterization of Fapy-dG within oligodeoxynucleotides: differential anomeric impacts on DNA duplex properties

K. Breslauer, F. Johnson, D. P. Remeta, 2011, Nucleic acids research.

Structure and stability of DNA containing an aristolactam II-dA lesion: implications for the NER recognition of bulky adducts

F. Johnson, M. Lukin, C. R. de los Santos, 2011, Nucleic acids research.

NMR solution structures of bistranded abasic site lesions in DNA.

C. R. de los Santos, K. Tian, R. D. Hazel, 2008, Biochemistry.

Effect of 6-thioguanine on the stability of duplex DNA

J. Bohon, Jen Bohon, Carlos R. de los Santos, 2005, Nucleic acids research.

Structural effect of the anticancer agent 6-thioguanine on duplex DNA.

J. Bohon, Jen Bohon, Carlos R de los Santos, 2003, Nucleic acids research.

Nuclear magnetic resonance structural studies of A.AT base triple alignments in intramolecular purine.purine.pyrimidine DNA triplexes in solution.

D. Patel, I. Radhakrishnan, C. R. de los Santos, 1993, Journal of molecular biology.

Use of an internal reference in 13C chemical shift measurements

E. Marceca, C. R. de los Santos, D. de Kowalewski, 1990 .

NMR structures of damaged DNA.

M. Lukin, Mark Lukin, Carlos de los Santos, 2006, Chemical reviews.

Stereoselective excision of thymine glycol lesions by mammalian cell extracts.

C. Iden, T. Rosenquist, R. Rieger, 2004, DNA repair.

Solution structure of duplex DNA containing an extrahelical abasic site analog determined by NMR spectroscopy and molecular dynamics.

A. Grollman, C. R. de los Santos, Z. Lin, 1998, Nucleic acids research.

Sorting the consequences of ionizing radiation: processing of 8-oxoguanine/abasic site lesions.

C. R. de los Santos, K. Tian, M. Mctigue, 2002, DNA repair.

Incorporation of 3-Aminobenzanthrone into 2′-Deoxyoligonucleotides and Its Impact on Duplex Stability

F. Johnson, M. Lukin, C. R. de los Santos, 2011, Journal of nucleic acids.

Structure and stability of duplex DNA containing the 3-(deoxyguanosin-N2-yl)-2-acetylaminofluorene (dG(N2)-AAF) lesion: a bulky adduct that persists in cellular DNA.

F. Johnson, R. Bonala, C. R. de los Santos, 2006, Chemical research in toxicology.

NMR structure of duplex DNA containing the alpha-OH-PdG.dA base pair: a mutagenic intermediate of acrolein.

F. Johnson, M. Lukin, C. R. de los Santos, 2012, Biopolymers.

Solution structure of an 11-mer duplex containing the 3, N(4)-ethenocytosine adduct opposite 2'-deoxycytidine: implications for the recognition of exocyclic lesions by DNA glycosylases.

F. Johnson, C. R. de los Santos, D. Cullinan, 2000, Journal of molecular biology.

138 2′-Deoxyguanine analogs which enhance hybridization oligonucleotides with complementary DNA

M. Lukin, C. R. de los Santos, Tatiana Zaliznyak, 2015, Journal of Biomolecular Structure and Dynamics.

Carbon-13 nuclear magnetic resonance analysis of [1-13C]glucose metabolism in Trypanosoma cruzi. Evidence of the presence of two alanine pools and of two CO2 fixation reactions.

J. Cazzulo, J. Cannata, B. Frydman, 1990, European journal of biochemistry.

Identification of a reduction product of aristolochic acid: implications for the metabolic activation of carcinogenic aristolochic acid.

J. Quirke, H. Priestap, C. R. de los Santos, 2010, Journal of natural products.

Molecular simulations reveal a common binding mode for glycosylase binding of oxidatively damaged DNA lesions.

C. Simmerling, A. Grollman, Kun Song, 2007, Journal of the American Chemical Society.

Impact of the C1' configuration of abasic sites on DNA duplex structure.

F. Johnson, C. R. de los Santos, K. Tian, 2004, Biochemistry.

Structure of an 11-mer DNA Duplex Containing the Carbocyclic Nucleotide Analog: 2′-Deoxyaristeromycin

F. Johnson, S. Smirnov, C. R. de los Santos, 2000, Journal of biomolecular structure & dynamics.

NMR solution structures of clustered abasic site lesions in DNA: structural differences between 3'-staggered (-3) and 5'-staggered (+3) bistranded lesions.

C. R. de los Santos, R. D. Hazel, 2010, Biochemistry.

NMR characterization of clustered bistrand abasic site lesions: effect of orientation on their solution structure.

C. R. de los Santos, Z. Lin, Z. Lin, 2001, Journal of molecular biology.

Active destabilization of base pairs by a DNA glycosylase wedge initiates damage recognition

C. Simmerling, Christina Bergonzo, A. Grollman, 2014, Nucleic acids research.

Solution structure of DNA containing α-OH-PdG: the mutagenic adduct produced by acrolein

F. Johnson, S. Attaluri, C. R. de los Santos, 2009, Nucleic acids research.

Solution structure of a DNA duplex containing the exocyclic lesion 3,N4-etheno-2'-deoxycytidine opposite 2'-deoxyguanosine.

F. Johnson, A. Grollman, M. Eisenberg, 1997, Biochemistry.