M. Morcillo

发表

Optimization of the pharmacophore model for 5-HT7R antagonism. Design and synthesis of new naphtholactam and naphthosultam derivatives.

L. Pardo, J. Lavandera, J. Ramos, 2003, Journal of medicinal chemistry.

Synthesis of new derivatives of -carboline-hydantoin

M. Braña, M. Morcillo, M. Garrido, 1990 .

Synthesis and structure-activity relationships of a new model of arylpiperazines. 4. 1-[omega-(4-Arylpiperazin-1-yl)alkyl]-3-(diphenylmethylene) - 2, 5-pyrrolidinediones and -3-(9H-fluoren-9-ylidene)-2, 5-pyrrolidinediones: study of the steric requirements of the terminal amide fragment on 5-HT1A af

M. López-Rodríguez, A. Sanz, L. Orensanz, 1999, Journal of medicinal chemistry.

Synthesis and structure-activity relationships of a new model of arylpiperazines. 2. Three-dimensional quantitative structure-activity relationships of hydantoin-phenylpiperazine derivatives with affinity for 5-HT1A and alpha 1 receptors. A comparison of CoMFA models.

M. López-Rodríguez, K. Schaper, B. Benhamú, 1997, Journal of medicinal chemistry.

Synthesis and structure-activity relationships of a new model of arylpiperazines. 1. 2-[[4-(o-methoxyphenyl)piperazin-1-yl]methyl]-1, 3-dioxoperhydroimidazo[1,5-alpha]pyridine: a selective 5-HT1A receptor agonist.

J. Manzanares, M. López-Rodríguez, A. Sanz, 1996, Journal of medicinal chemistry.

Michael additions to acrylonitrile, methyl acrylate and methyl vinyl ketone to Nb-benzylidenetryptophan methyl ester

M. Braña, M. Morcillo, M. Garrido, 1990 .

Synthesis, structure and cytostatic activity of a series of 2-substituted perimidines

G. Klebe, M. Braña, M. Morcillo, 1990 .

Novel benzimidazole-4-carboxylic acid derivatives as potent and selective 5-HT3 receptor ligands

M. López-Rodríguez, M. Morcillo, B. Benhamú, 1996 .

Synthesis and structure-activity relationships of a new model of arylpiperazines. 3.1 2-[omega-(4-arylpiperazin-1-yl)alkyl]perhydropyrrolo- [1,2-c]imidazoles and -perhydroimidazo[1,5-a]pyridines: study of the influence of the terminal amide fragment on 5-HT1A affinity/selectivity.

M. López-Rodríguez, M. Murcia, A. Sanz, 1997, Journal of medicinal chemistry.

Reaction of 6-hydroxytetrahydro-beta-carboline-3-carboxylic acids with isocyanates and isothiocyanates.

B. Benhamú, L. Orensanz, E. Fernández, 1994, Chemical & pharmaceutical bulletin.

1-[omega-(4-arylpiperazin-1-yl)alkyl]-3-diphenylmethylene-2,5- pyrrolidinediones as 5-HT1A receptor ligands: study of the steric requirements of the terminal amide fragment on 5-HT1A affinity/selectivity.

M. López-Rodríguez, L. Orensanz, E. Fernández, 1998, Bioorganic & medicinal chemistry letters.

Reaction of 5-hydroxy-L-tryptophan with alkyl isocyanates

M. Braña, M. Morcillo, M. Garrido, 1987 .

Arylpiperazine derivatives acting at 5-HT(1A) receptors.

M. López-Rodríguez, A. Viso, B. Benhamú, 2002, Current medicinal chemistry.

First pharmacophoric hypothesis for 5-HT7 antagonism.

J. Lavandera, J. Ramos, M. López-Rodríguez, 2000, Bioorganic & medicinal chemistry letters.

Synthesis and structure-activity relationships of a new model of arylpiperazines. Study of the 5-HT(1a)/alpha(1)-adrenergic receptor affinity by classical hansch analysis, artificial neural networks, and computational simulation of ligand recognition.

L. Pardo, M. López-Rodríguez, K. Schaper, 2001, Journal of medicinal chemistry.

5-HT(4) receptor antagonists: structure-affinity relationships and ligand-receptor interactions.

L. Pardo, M. López-Rodríguez, A. Viso, 2002, Current topics in medicinal chemistry.

Benzimidazole derivatives. Part 1: Synthesis and structure-activity relationships of new benzimidazole-4-carboxamides and carboxylates as potent and selective 5-HT4 receptor antagonists.

M. López-Rodríguez, A. Viso, M. Murcia, 1999, Bioorganic & medicinal chemistry.

Synthesis, structure and cytostatic activity of a series of N-substituted 3,4-diphenyl-1H-pyrrole-2,5-diones.

M. Morcillo, M. Fernández Braña, M. Garrido, 1989, Chemical & pharmaceutical bulletin.

Synthesis, Structure, and Cytostatic Activity of a Series of N-Substituted 3,4-Diphenyl-1H-pyrrole-2,5-diones.

M. Braña, M. Morcillo, M. Garrido, 1990 .

Design and synthesis of S-(-)-2-[[4-(napht-1-yl)piperazin-1-yl]methyl]-1,4-dioxoperhydropyrrolo[1,2-a]pyrazine (CSP-2503) using computational simulation. A 5-HT1A receptor agonist.

M. Delgado, L. Pardo, J. Manzanares, 2003, Bioorganic & medicinal chemistry letters.

Reaction of L-Tryptophan with Alkyl Isocyanates

M. Braña, M. Morcillo, M. Garrido, 1987 .

Reaction of L-Tryptophan with Alkyl Isocyanates.

M. Braña, M. Morcillo, M. Garrido, 1987 .

Serotonin 5-HT7 Receptor Antagonists

L. Pardo, J. Lavandera, M. López-Rodríguez, 2004 .

Benzimidazole derivatives. Part 5: design and synthesis of new benzimidazole-arylpiperazine derivatives acting as mixed 5-HT1A/5-HT3 ligands.

M. López-Rodríguez, B. Benhamú, L. Schiapparelli, 2004, Bioorganic & medicinal chemistry.