H. Manabe

发表

Administration of PDE4 Inhibitors Suppressed the Pannus-Like Inflammation by Inhibition of Cytokine Production by Macrophages and Synovial Fibroblast Proliferation

T. Suda, Katsuya Kobayashi, I. Miki, 2007, Mediators of inflammation.

KF19514, a phosphodiesterase 4 and 1 inhibitor, inhibits TNF-α-induced GM-CSF production by a human bronchial epithelial cell line via inhibition of PDE4

K. Sasaki, H. Manabe, 2003, Inflammation Research.

Differential effects of PDE4 inhibitors on cortical neurons and T-lymphocytes.

M. Ichimura, K. Yanagawa, H. Manabe, 2008, Journal of pharmacological sciences.

Correlation between emetic effect of phosphodiesterase 4 inhibitors and their occupation of the high-affinity rolipram binding site in Suncus murinus brain.

M. Ichimura, H. Nonaka, K. Yanagawa, 2007, European journal of pharmacology.

First-pass of GTS-21 on canine gut wall and liver determined by portal-systemic concentration difference.

H. Kiwada, H. Manabe, M. Komuro, 2001, European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences.

Inhibitory Effect of the 4-Aminotetrahydroquinoline Derivatives, Selective Chemoattractant Receptor-Homologous Molecule Expressed on T Helper 2 Cell Antagonists, on Eosinophil Migration Induced by Prostaglandin D2

E. Fuse, S. Tashiro, M. Sawada, 2005, Journal of Pharmacology and Experimental Therapeutics.

The Phosphodiesterase 4 Inhibitor Prevents Antigen-induced Biphasic Nasal Obstruction in Brown Norway Rats

H. Manabe, H. Kawasaki, T. Kaise, 2005 .

[Recent development of new drugs for the treatment of allergic diseases].

D. Harada, H. Manabe, E. Ohshima, 2004, Nihon yakurigaku zasshi. Folia pharmacologica Japonica.

The inhaled administration of KF19514, a phosphodiesterase 4 and 1 inhibitor, prevents antigen-induced lung inflammation in guinea pigs.

H. Manabe, H. Kawasaki, K. Akuta, 2000, Pulmonary pharmacology & therapeutics.

Oxatomide inhibits the release of chemical mediators from human lung tissues and from granulocytes.

H. Manabe, S. Yoshida, H. Tomioka, 1988, International archives of allergy and applied immunology.

The effect of erdosteine and its active metabolite on reactive oxygen species production by inflammatory cells

H. Manabe, K. Miyake, K. Akuta, 1999, Inflammation Research.

Gabapentin and pregabalin inhibit the itch-associated response induced by the repeated application of oxazolone in mice.

H. Yano, H. Manabe, H. Miura, 2011, Journal of pharmacological sciences.

Inhibitory effect of the 4-aminotetrahydroquinoline derivatives , selective CRTH 2 antagonists , on eosinophil migration induced by prostaglandin D 2

E. Fuse, S. Tashiro, M. Sawada, 2005 .

Optimum Pain Relief With Continuous Epidural Infusion of Local Anesthetics Shortens the Duration of Zoster-Associated Pain

H. Manabe, S. Shono, K. Higa, 2004, The Clinical journal of pain.

Guidelines on Treatment of Herpes Zoster

J. Kato, H. Manabe, K. Higa, 2001 .

Severity of skin lesions of herpes zoster at the worst phase rather than age and involved region most influences the duration of acute herpetic pain

H. Manabe, K. Higa, K. Dan, 1997, Pain.

Treatment of Acute Herpes Zoster

H. Manabe, Kenshiro Hirata, Katsusuke Kume, 2008 .

Continuous Epidural Infusion of Local Anesthetics and Shorter Duration of Acute Zoster‐Associated Pain

H. Manabe, K. Higa, K. Dan, 1995, The Clinical journal of pain.

Effect of KW-4679, an orally active anti-allergic drug, on antigen-induced airway hyperresponsiveness in actively sensitized guinea pigs.

H. Manabe, H. Kawasaki, K. Ohmori, 1996, Japanese journal of pharmacology.

Staphylococcus aureus peptidoglycan stimulates granulocyte macrophage colony‐stimulating factor production from human epidermal keratinocytes via mitogen‐activated protein kinases

D. Harada, H. Manabe, M. Matsubara, 2004, FEBS letters.

Analyses of a mouse model of the dermatitis caused by 2,4,6-trinitro-1-chlorobenzene (TNCB)-repeated application.

C. Takada, D. Harada, H. Manabe, 2005, Journal of dermatological science.

New bronchodilators. 3. Imidazo[4,5-c][1,8]naphthyridin-4(5H)-ones.

H. Kase, S. Kitamura, M. Ichimura, 1992, Journal of medicinal chemistry.

New bronchodilators. 1. 1,5-Substituted 1H-imidazo[4,5-c]quinolin-4(5H)-ones.

S. Kitamura, F. Suzuki, H. Manabe, 1992, Journal of medicinal chemistry.

KF 19514 , a phosphodiesterase 4 and 1 inhibitor , inhibits TNF-a-induced GM-CSF production by a human bronchial epithelial cell line via inhibition of PDE 4

K. Sasaki, H. Manabe, 2022 .

Effect of orally administered KF66490, a phosphodiesterase 4 inhibitor, on dermatitis in mouse models.

Katsuya Kobayashi, C. Takada, D. Harada, 2009, International immunopharmacology.

Stellate Ganglion Block for the Treatment of Acute Herpetic Pain Involving the Trigeminal and Cervical Regions

H. Manabe, K. Higa, K. Dan, 1994 .

Varicella‐zoster virus infections during pregnancy: Hypothesis concerning the mechanisms of congenital malformations

H. Manabe, K. Higa, K. Dan, 1987, Obstetrics and gynecology.

The effects of olopatadine hydrochloride on the number of scratching induced by repeated application of oxazolone in mice.

T. Tamura, H. Manabe, T. Amano, 2005, European journal of pharmacology.

Fetal varicella syndrome.

H. Manabe, K. Higa, K. Dan, 1988, The Journal of pediatrics.

Effect of orally administered rolipram, a phosphodiesterase 4 inhibitor, on a mouse model of the dermatitis caused by 2,4,6-trinitro-1-chlorobenzene (TNCB)-repeated application.

D. Harada, H. Manabe, Yukihito Tsukumo, 2006, European journal of pharmacology.

Factors influencing the duration of treatment of acute herpetic pain with sympathetic nerve block: Importance of severity of herpes zoster assessed by the maximum antibody titers to varicella-zoster virus in otherwise healthy patients

H. Manabe, K. Higa, K. Dan, 1988, Pain.

T-lymphocyte subsets in otherwise healthy patients with herpes zoster and relationships to the duration of acute herpetic pain

H. Manabe, K. Higa, K. Dan, 1992, Pain.

Curative effects of phosphodiesterase 4 inhibitors cilomilast, roflumilast, and rolipram in dermatitis mouse model.

Katsuya Kobayashi, D. Harada, H. Manabe, 2008, Journal of dermatological science.

KW-4679, an antiallergic drug, inhibits the production of inflammatory lipids in human polymorphonuclear leukocytes and guinea pig eosinophils.

I. Miki, H. Ishii, H. Kase, 1996, International archives of allergy and immunology.

Pharmacological characterization of itch-associated response induced by repeated application of oxazolone in mice.

D. Harada, H. Manabe, Yukihito Tsukumo, 2010, Journal of pharmacological sciences.

Effects of KW-4679, a new orally active antiallergic drug, on antigen-induced bronchial hyperresponsiveness, airway inflammation and immediate and late asthmatic responses in guinea pigs.

H. Ishii, S. Kitamura, H. Manabe, 1996, International archives of allergy and immunology.

The effects of preoperative alcohol, tobacco, and psychological stress on postoperative complications: a prospective observational study

Y. Osaki, H. Manabe, Y. Myoga, 2021, BMC Anesthesiology.

Inhibitory effect of oxatomide on oxygen-radical generation and peptide-leukotriene release from guinea pig eosinophils.

H. Manabe, K. Ohmori, K. Akuta-Ohnuma, 1998, Arzneimittel-Forschung.

Anti-inflammatory and bronchodilator properties of KF19514, a phosphodiesterase 4 and 1 inhibitor.

H. Kase, S. Kitamura, M. Ichimura, 1997, European journal of pharmacology.

Prognostic clinical signs in herpes zoster pain

H. Manabe, K. Higa, K. Dan, 1987, PAIN.

Antiinflammatory and antiallergic effects of a novel metabolite of Nocardiopsis sp. as a potent protein kinase C inhibitor from microbial origin.

H. Ishii, H. Kase, T. Tamura, 1988, Arzneimittel-Forschung.

[The effect of KW-4679, an antiallergic drug, on experimental allergic rhinitis].

H. Manabe, T. Kaise, K. Ohmori, 1995, Arerugi = [Allergy].

Immunopharmacological properties of a new antiallergic agent KW-4679

Yasuo Sasaki, K. Ohmori, Hidee Ishii, 1988 .

Two Cases of Liver Dysfunction after Intravenous Injection of Acyclovir for Acute Herpes Zoster

H. Manabe, K. Hirota, K. Higa, 1998 .

Herpes zoster in a patient with mixed connective tissue disease

H. Manabe, K. Higa, K. Dan, 1994 .

T-lymphocyte subsets in otherwise healthy patients with herpes zoster and relationships to the duration of acute herpetic pain

H. Manabe, K. Higa, K. Dan, 1992, Pain.