J. Schardt

发表

Improving antibody drug development using bionanotechnology.

Emily K Makowski, Peter M. Tessier, J. Schardt, 2021, Current opinion in biotechnology.

CD44 Promotes Inflammation and Extracellular Matrix Production During Arteriovenous Fistula Maturation

Michael R. Hall, Steven M. Jay, Clinton D. Protack, 2017, Arteriosclerosis, thrombosis, and vascular biology.

Rapid and Quantitative In Vitro Evaluation of SARS-CoV-2 Neutralizing Antibodies and Nanobodies.

J. Zhang, M. K. Oo, Xiaotian Tan, 2022, Analytical chemistry.

Co-optimization of therapeutic antibody affinity and specificity using machine learning models that generalize to novel mutational space

Patrick C. Kinnunen, J. Linderman, Yulei Zhang, 2022, Nature Communications.

Discovery and characterization of high-affinity, potent SARS-CoV-2 neutralizing antibodies via single B cell screening

Kyung Soo Park, M. Cascalho, J. Moon, 2021, Scientific Reports.

Homologous quorum sensing regulatory circuit (hQSRC): A dual-input genetic controller for modulating quorum sensing (QS)-mediated protein expression in E. coli.

Kristina T. Stephens, W. Bentley, Eric VanArsdale, 2020, ACS synthetic biology.

HER3-Targeted Affibodies with Optimized Formats Reduce Ovarian Cancer Progression in a Mouse Xenograft Model

S. Lipkowitz, S. Jay, R. Lapidus, 2019, The AAPS Journal.

A platform of genetically engineered bacteria as vehicles for localized delivery of therapeutics: Toward applications for Crohn's disease

W. Bentley, G. Payne, M. Chang, 2018, Bioengineering & translational medicine.

Agonist antibody discovery: experimental, computational, and rational engineering approaches.

P. Tessier, J. Schardt, Matthew D. Smith, 2021, Drug discovery today.

Directed evolution of potent neutralizing nanobodies against SARS-CoV-2 using CDR-swapping mutagenesis

M. Cascalho, A. Tai, P. Tessier, 2021, Cell Chemical Biology.

Oncogene Knockdown via Active Loading of Small RNAs into Extracellular Vesicles by Sonication

S. Jay, N. Arumugasaamy, Natalie K. Livingston, 2016, Cellular and Molecular Bioengineering.

Oncogene Knockdown via Active Loading of Small RNAs into Extracellular Vesicles by Sonication

S. Jay, N. Arumugasaamy, Natalie K. Livingston, 2016, Cellular and molecular bioengineering.

Emerging roles for extracellular vesicles in tissue engineering and regenerative medicine.

Steven M Jay, Sonja Sokic, S. Jay, 2015, Tissue engineering. Part B, Reviews.

Engineered Multivalent Nanobodies Potently and Broadly Neutralize SARS‐CoV‐2 Variants

M. Cascalho, P. Tessier, T. Lanigan, 2021, Advanced therapeutics.

HER3-Targeted Affibodies with Optimized Formats Reduce Ovarian Cancer Progression in a Mouse Xenograft Model

S. Lipkowitz, A. Hussain, S. Jay, 2019, The AAPS Journal.

Engineered Multivalency Enhances Affibody-Based HER3 Inhibition and Downregulation in Cancer Cells.

S. Lipkowitz, A. Hussain, S. Jay, 2017, Molecular pharmaceutics.

Mutational analysis of SARS-CoV-2 variants of concern reveals key tradeoffs between receptor affinity and antibody escape

Peter M. Tessier, J. Schardt, Matthew D. Smith, 2022, PLoS Comput. Biol..

ENGINEERED MULTIVALENCY FOR ENHANCED AFFIBODY-BASED HER3 CANCER THERAPY

J. Schardt, 2018 .

Optimization of therapeutic antibodies for reduced self-association and non-specific binding via interpretable machine learning.

Peter M. Tessier, J. Schardt, J. Zupancic, 2023, Nature biomedical engineering.

Monoclonal Antibody Generation Using Single B Cell Screening for Treating Infectious Diseases.

Peter M. Tessier, J. Schardt, Neelan S Sivaneri, 2024, BioDrugs : clinical immunotherapeutics, biopharmaceuticals and gene therapy.

Facile generation of biepitopic antibodies with intrinsic agonism for activating tumor necrosis factor receptors.

Peter M. Tessier, J. Schardt, Alec A. Desai, 2024, Cell chemical biology.

Facile generation of biepitopic antibodies with intrinsic agonism for activating receptors in the tumor necrosis factor superfamily

Peter M. Tessier, J. Schardt, Alec A. Desai, 2023, bioRxiv.