Katharina Sylvester

发表

Cell‐permeable high‐affinity tracers for Gq proteins provide structural insights, reveal distinct binding kinetics and identify small molecule inhibitors

C. Müller, B. Fleischmann, M. Gütschow, 2019, British journal of pharmacology.

Small-Molecule Thioesters as SARS-CoV-2 Main Protease Inhibitors: Enzyme Inhibition, Structure–Activity Relationships, Antiviral Activity, and X-ray Structure Determination

Yechun Xu, A. Poso, M. Gütschow, 2022, Journal of medicinal chemistry.

Discovery and Crystallographic Studies of Trisubstituted Piperazine Derivatives as Non-Covalent SARS-CoV-2 Main Protease Inhibitors with High Target Specificity and Low Toxicity

Dongwei Kang, P. Zhan, Xinyong Liu, 2022, Journal of medicinal chemistry.

Targeting the Main Protease of SARS‐CoV‐2: From the Establishment of High Throughput Screening to the Design of Tailored Inhibitors

A. Schiedel, C. Müller, M. Gütschow, 2021, Angewandte Chemie.

Diindolylmethane Derivatives: Potent Agonists of the Immunostimulatory Orphan G Protein-Coupled Receptor GPR84.

Meryem Köse, C. Müller, H. Weighardt, 2017, Journal of medicinal chemistry.

2‐Substituted thienotetrahydropyridine derivatives: Allosteric ectonucleotidase inhibitors

M. Gütschow, J. Sévigny, J. Pelletier, 2021, Archiv der Pharmazie.

6-(Ar)Alkylamino-Substituted Uracil Derivatives: Lipid Mimetics with Potent Activity at the Orphan G Protein-Coupled Receptor 84 (GPR84)

Meryem Köse, C. Müller, I. von Kügelgen, 2018, ACS omega.

Synthesis and structure-activity relationships of ticlopidine derivatives and analogs as inhibitors of ectonucleotidase CD39.

J. Sévigny, J. Pelletier, Thanigaimalai Pillaiyar, 2023, Bioorganic chemistry.

Discovery and Crystallographic Studies of Nonpeptidic Piperazine Derivatives as Covalent SARS-CoV-2 Main Protease Inhibitors

Dongwei Kang, P. Zhan, Xinyong Liu, 2022, Journal of medicinal chemistry.

An agonist radioligand for the proinflammatory lipid-activated G protein-coupled receptor GPR84 providing structural insights.

Meryem Köse, C. Müller, I. von Kügelgen, 2019, Journal of medicinal chemistry.

Heparins are potent inhibitors of ectonucleotide pyrophosphatase/phospho-diesterase-1 (NPP1) – a promising target for the immunotherapy of cancer

J. Pelletier, G. Bendas, O. Vanakker, 2023, Frontiers in immunology.