J. Beck

发表

The Toxoplasma Dense Granule Proteins GRA17 and GRA23 Mediate the Movement of Small Molecules between the Host and the Parasitophorous Vacuole.

G. Bett, A. Bougdour, S. Sidik, 2015, Cell host & microbe.

Small-molecule inhibition of a depalmitoylase enhances Toxoplasma host-cell invasion

Megan C. Garland, M. Bogyo, J. Boothroyd, 2013, Nature chemical biology.

Cytoskeleton assembly in Toxoplasma gondii cell division.

M. Gubbels, P. Bradley, Chun-Ti Chen, 2012, International review of cell and molecular biology.

Bottom-up structural proteomics: cryoEM of protein complexes enriched from the cellular milieu

Z. Zhou, D. Goldberg, T. Terwilliger, 2019, Nature Methods.

A Novel Family of Toxoplasma IMC Proteins Displays a Hierarchical Organization and Functions in Coordinating Parasite Division

P. Bradley, N. Morrissette, M. Huynh, 2010, PLoS pathogens.

TurboID Identification of Evolutionarily Divergent Components of the Nuclear Pore Complex in the Malaria Model Plasmodium berghei

J. Beck, G. Mair, Sushma V. Ambekar, 2022, mBio.

A SAS-6-Like Protein Suggests that the Toxoplasma Conoid Complex Evolved from Flagellar Components

B. Wickstead, K. Gull, P. Bradley, 2013, Eukaryotic Cell.

The PTEX Pore Component EXP2 Is Important for Intrahepatic Development during the Plasmodium Liver Stage

Ryan C. Smith, J. M. Beck, J. Beck, 2022, bioRxiv.

TurboID Identification of Evolutionarily Divergent Components of the Nuclear Pore Complex in the Malaria Model Plasmodium berghei

J. Beck, G. Mair, Sushma V. Ambekar, 2022, mBio.

A novel knock sideways approach for Plasmodium secreted proteins reveals a surprising insensitivity to vacuolar depletion of PTEX component HSP101

J. Beck, M. Fierro, Tahir Hussain, 2022, bioRxiv.

Purification, crystallization and preliminary X-ray diffraction analysis of inner membrane complex (IMC) subcompartment protein 1 (ISP1) from Toxoplasma gondii.

P. Bradley, M. Tonkin, M. Boulanger, 2012, Acta crystallographica. Section F, Structural biology and crystallization communications.

RON5 Is Critical for Organization and Function of the Toxoplasma Moving Junction Complex

P. Bradley, J. Beck, Elliot W. Kim, 2014, PLoS pathogens.

Toxoplasma ISP4 is a central IMC sub-compartment protein whose localization depends on palmitoylation but not myristoylation.

P. Bradley, Connie Fung, J. Beck, 2012, Molecular and biochemical parasitology.

The Toxoplasma Dense Granule Proteins GRA 17 and GRA 23 Mediate the Movement of Small Molecules between the Host and the Parasitophorous Vacuole Graphical

G. Bett, A. Bougdour, S. Sidik, 2015 .

Knock-sideways by inducible ER retrieval reveals a novel extra-vacuolar function for Plasmodium PTEX component HSP101

J. Beck, M. Fierro, Tahir Hussain, 2022, bioRxiv.

Intervacuolar Transport and Unique Topology of GRA14, a Novel Dense Granule Protein in Toxoplasma gondii

P. Webster, P. Bradley, J. Beck, 2008, Infection and Immunity.

Exploitation of a newly-identified entry pathway into the malaria parasite-infected erythrocyte to inhibit parasite egress

D. Goldberg, J. Zimmerberg, R. Fairhurst, 2017, Scientific Reports.

EXP1 is required for organisation of EXP2 in the intraerythrocytic malaria parasite vacuole

D. Goldberg, J. Wohlschlegel, T. Nessel, 2020, Cellular microbiology.

EXP1 is required for organization of the intraerythrocytic malaria parasite vacuole

D. Goldberg, J. Wohlschlegel, T. Nessel, 2019, bioRxiv.

The parasitophorous vacuole of the blood-stage malaria parasite

M. Blackman, J. Beck, J. M. Matz, 2020, Nature Reviews Microbiology.

Flagellar Components from Toxoplasma Conoid Complex Evolved A SAS-6-Like Protein Suggests that the

Cruz Vargas de León, W. Beatty, J. Beck, 2014 .

The Inner Membrane Complex Sub-compartment Proteins Critical for Replication of the Apicomplexan Parasite Toxoplasma gondii Adopt a Pleckstrin Homology Fold*

P. Bradley, M. Tonkin, M. Boulanger, 2014, The Journal of Biological Chemistry.

Homology Fold Adopt a Pleckstrin Toxoplasma gondii Replication of the Apicomplexan Parasite Sub-compartment Proteins Critical for The Inner Membrane Complex Protein Structure and Folding :

P. Bradley, M. Tonkin, M. Boulanger, 2014 .

The chaperonin TRiC forms an oligomeric complex in the malaria parasite cytosol

D. Goldberg, Natalie J. Spillman, J. Niles, 2017, Cellular microbiology.

The parasitophorous vacuole of the blood-stage malaria parasite

M. Blackman, J. Beck, J. M. Matz, 2020, Nature Reviews Microbiology.

PTEX component HSP101 mediates export of diverse malaria effectors into host erythrocytes

D. Goldberg, V. Muralidharan, A. Oksman, 2014, Nature.

Plasmodium Niemann-Pick type C1-related protein is a druggable target required for parasite membrane homeostasis

E. Winzeler, A. Vaidya, M. Llinás, 2019, eLife.

Discovery of small molecule inhibitors of Plasmodium falciparum apicoplast DNA polymerase

R. Honzatko, S. Nelson, Anuradha Roy, 2022, bioRxiv.

Protein export into malaria parasite-infected erythrocytes: mechanisms and functional consequences.

D. Goldberg, Natalie J. Spillman, J. Beck, 2015, Annual review of biochemistry.

Promising Antimalarials targeting Apicoplast DNA Polymerase from Plasmodium falciparum

R. Honzatko, Supreet Kaur, J. M. Beck, 2022, bioRxiv.

Plasmodium falciparum Niemann-Pick Type C1-Related Protein is a Druggable Target Required for Parasite Membrane Homeostasis

E. Winzeler, A. Vaidya, M. Llinás, 2018, bioRxiv.

Transport mechanisms at the malaria parasite-host cell interface

J. Beck, Chi-Min Ho, 2021, PLoS pathogens.

Malaria Parasite Translocon Structure and Mechanism of Effector Export

Daniel E. Goldberg, D. Goldberg, M. Lai, 2018, Nature.

HSP101/PTEX mediates export of diverse malaria effector proteins into the host erythrocyte

D. Goldberg, V. Muralidharan, A. Oksman, 2014, Nature.

Dramatic Consequences of Reducing Erythrocyte Membrane Cholesterol on Plasmodium falciparum

Joanne M. Morrisey, A. Vaidya, J. Morrisey, 2022, bioRxiv.

Cholesterol dynamics are essential for the growth and development of Plasmodium falciparum within the erythrocyte

A. Vaidya, J. Morrisey, J. Beck, 2021 .

EXP 2 is a nutrient-permeable channel in the vacuolar membrane of Plasmodium and is essential for protein export via

D. Goldberg, J. Zimmerberg, J. Niles, 2018 .

Native structure of the RhopH complex, a key determinant of malaria parasite nutrient acquisition

Z. Zhou, D. Goldberg, M. Lai, 2021, Proceedings of the National Academy of Sciences.

Contacting domains segregate a lipid transporter from a solute transporter in the malarial host–parasite interface

E. Istvan, D. Goldberg, J. Zimmerberg, 2020, Nature Communications.

Bottom-up structural proteomics: cryoEM of protein complexes enriched from the cellular milieu

Z. Zhou, D. Goldberg, T. Terwilliger, 2019, Nature Methods.

A Toxoplasma Palmitoyl Acyl Transferase and the Palmitoylated Armadillo Repeat Protein TgARO Govern Apical Rhoptry Tethering and Reveal a Critical Role for the Rhoptries in Host Cell Invasion but Not Egress

I. Coppens, A. Vashisht, J. Wohlschlegel, 2013, PLoS pathogens.

A new species of antbird (Passeriformes: Thamnophilidae) from the Cordillera Azul, San Martín, Peru

O. Johnson, J. Beck, A. Moncrieff, 2017, The Auk.

Plasmepsins IX and X are essential and druggable mediators of malaria parasite egress and invasion

N. Tolia, D. Fremont, D. Goldberg, 2017, Science.

MtcB, a member of the MttB superfamily from the human gut acetogen Eubacterium limosum, is a cobalamin‐dependent carnitine demethylase

D. Goldberg, Z. Zhou, M. Lai, 2020, The Journal of biological chemistry.

Knock-sideways by inducible ER retrieval enables a novel approach for studying Plasmodium secreted proteins

J. Beck, M. Fierro, Tahir Hussain, 2023, bioRxiv.

Contacting domains that segregate lipid from solute transporters in malaria parasites

D. Goldberg, J. Zimmerberg, Robyn Roth, 2019, bioRxiv.

Rounding precedes rupture and breakdown of vacuolar membranes minutes before malaria parasite egress from erythrocytes

D. Goldberg, J. Zimmerberg, J. Heuser, 2018, Cellular microbiology.

PEXEL is a proteolytic maturation site for both exported and non-exported Plasmodium proteins

J. Wohlschlegel, J. Sha, J. Beck, 2023, bioRxiv.

EXP2 is a nutrient-permeable channel in the vacuolar membrane of Plasmodium and is essential for protein export via PTEX

D. Goldberg, J. Zimmerberg, J. Niles, 2018, Nature Microbiology.

The Toxoplasma Dense Granule Proteins GRA17 and GRA23 Mediate the Movement of Small Molecules between the Host and the Parasitophorous Vacuole.

G. Bett, S. Sidik, Sebastian Lourido, 2015, Cell host & microbe.

Intervacuolar Transport and Unique Topology of GRA14, a Novel Dense Granule Protein in Toxoplasma gondii

P. Webster, P. Bradley, J. Beck, 2008, Infection and Immunity.

Nuclear pore complexes undergo Nup221 exchange during blood stage asexual replication of Plasmodium parasites

J. Beck, Sabrina Absalon, James Blauwkamp, 2024, bioRxiv.