E. Mertsching

发表

Systemic administration of an Fcgamma-Fc(epsilon)-fusion protein in house dust mite sensitive nonhuman primates.

M. Kehry, M. V. Van Scott, E. Mertsching, 2008, Clinical immunology.

A mouse strain defective for αβ versus γδ T cell lineage commitment

J. Marth, J. Esko, F. Ramsdell, 2002 .

An Intermediate pH Unfolding Transition Abrogates the Ability of IgE to Interact with Its High Affinity Receptor FcϵRIα*

S. Demarest, M. Kehry, J. Hopp, 2006, Journal of Biological Chemistry.

A mouse Fcγ-Fcε protein that inhibits mast cells through activation of FcγRIIB, SH2 domain–containing inositol phosphatase 1, and SH2 domain–containing protein tyrosine phosphatases

A. Saxon, H. Hess, M. Kehry, 2008 .

IL-7 transgenic mice: analysis of the role of IL-7 in the differentiation of thymocytes in vivo and in vitro.

R. Ceredig, E. Mertsching, C. Burdet, 1995, International immunology.

Phenotypic and functional analysis of B lymphopoiesis in interleukin‐7‐transgenic mice: expansion of pro/pre‐B cell number and persistence of B lymphocyte development in lymph nodes and spleen

R. Ceredig, U. Grawunder, E. Mertsching, 1996, European journal of immunology.

T cell receptor α gene rearrangement and transcription in adult thymic γδ cells

H. Macdonald, R. Ceredig, Anne Wilson, 1997, European journal of immunology.

T cell receptor‐γδ‐expressing fetal mouse thymocytes are generated without T cell receptor Vβ selection

R. Ceredig, E. Mertsching, 1996 .

A pTα‐Negative Subpopulation of CD25+ TN Thymocytes Revealed by a Transgenic Marker

I. Mårtensson, R. Ceredig, E. Mertsching, 2002, Scandinavian journal of immunology.

Interleukin-7, a non-redundant potent cytokine whose over-expression massively perturbs B-lymphopoiesis.

R. Ceredig, J. Linares, R. Ceredig, 1998, International reviews of immunology.

Optimization of novel reversible Bruton's tyrosine kinase inhibitors identified using Tethering-fragment-based screens.

L. Silvian, T. Bohnert, D. Erlanson, 2019, Bioorganic & medicinal chemistry.

Caspase‐8 Variant G Regulates Rheumatoid Arthritis Fibroblast‐Like Synoviocyte Aggressive Behavior

J. M. Sauder, Wei Wang, Rizi Ai, 2021, ACR open rheumatology.

Discovery of structural diverse reversible BTK inhibitors utilized to develop a novel in vivo CD69 and CD86 PK/PD mouse model.

George H Vandeveer, N. Powell, L. Silvian, 2022, Bioorganic & medicinal chemistry letters.

Utilizing structure based drug design and metabolic soft spot identification to optimize the in vitro potency and in vivo pharmacokinetic properties leading to the discovery of novel reversible Bruton's tyrosine kinase inhibitors.

Y. Liu, L. Silvian, T. Bohnert, 2021, Bioorganic & medicinal chemistry.

Structures of human Bruton's tyrosine kinase in active and inactive conformations suggest a mechanism of activation for TEC family kinases

L. Silvian, D. Baker, V. Hong, 2010, Protein science : a publication of the Protein Society.

Serum-circulating His-tRNA synthetase inhibits organ-targeted immune responses

K. Ogilvie, K. Chiang, P. Jakobsson, 2019, Cellular & Molecular Immunology.

A mouse Fcgamma-Fcepsilon protein that inhibits mast cells through activation of FcgammaRIIB, SH2 domain-containing inositol phosphatase 1, and SH2 domain-containing protein tyrosine phosphatases.

A. Saxon, H. Hess, M. Kehry, 2008, The Journal of allergy and clinical immunology.

A mouse strain defective for alphabeta versus gammadelta T cell lineage commitment.

J. Marth, J. Esko, F. Ramsdell, 2002, International immunology.