T. Virtanen

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Level of airborne bovine epithelial antigen in Finnish cowsheds

K. Husman, R. Mäntyjärvi, T. Virtanen, 1988, International archives of occupational and environmental health.

Association of HLA class II alleles with sensitization to cow dander Bos d 2, an important occupational allergen.

A. Kauppinen, Meinir G. Jones, T. Kinnunen, 2012, Immunobiology.

Allergy to lipocalins: a consequence of misguided T-cell recognition of self and nonself?

R. Mäntyjärvi, T. Zeiler, T. Virtanen, 1999, Immunology today.

Lipocalins as allergens.

R. Mäntyjärvi, T. Virtanen, J. Rautiainen, 2000, Biochimica et biophysica acta.

Microarrayed allergen molecules: diagnostic gatekeepers for allergy treatment

Wayne Thomas, Karin Hoffmann-Sommergruber, Reto Crameri, 2002, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Important Animal Allergens Are Lipocalin Proteins: Why Are They Allergenic?

R. Mäntyjärvi, T. Zeiler, T. Virtanen, 1999, International Archives of Allergy and Immunology.

Immunotherapy for pet allergies

T. Virtanen, 2018, Human vaccines & immunotherapeutics.

Prospects for peptide-based immunotherapy for dog allergy

T. Virtanen, 2006, Current opinion in allergy and clinical immunology.

Two new variants of the lipocalin allergen Bos d 2.

S. Auriola, R. Mäntyjärvi, A. Konttinen, 2001, Journal of chromatography. B, Biomedical sciences and applications.

Immunomodulatory potential of heteroclitic analogs of the dominant T-cell epitope of lipocalin allergen Bos d 2 on specific T cells.

A. Närvänen, W. Kwok, T. Kinnunen, 2005, International immunology.

Suboptimal recognition of a T cell epitope of the major dog allergen Can f 1 by human T cells.

B. Maillère, A. Kauppinen, A. Närvänen, 2009, Molecular immunology.

T cell epitopes of a lipocalin allergen colocalize with the conserved regions of the molecule.

P. Vilja, R. Mäntyjärvi, J. Kauppinen, 1999, Journal of immunology.

Immunotherapeutic potential of the immunodominant T‐cell epitope of lipocalin allergen Bos d 2 and its analogues

B. Maillère, A. Kauppinen, A. Närvänen, 2008, Immunology.

Sensitization of dairy farmers to bovine antigens and effects of exposure on specific IgG and IgE titers.

K. Husman, R. Mäntyjärvi, T. Virtanen, 1988, International archives of allergy and applied immunology.

Human CD4+ T Cell Responses to the Dog Major Allergen Can f 1 and Its Human Homologue Tear Lipocalin Resemble Each Other

B. Maillère, T. Kinnunen, T. Virtanen, 2014, PloS one.

Allergen‐specific naïve and memory CD4+ T cells exhibit functional and phenotypic differences between individuals with or without allergy

A. Närvänen, W. Kwok, T. Kinnunen, 2010, European journal of immunology.

Cat, dog, and house‐dust‐mite allergen levels of house dust in Finnish apartments

A. Pasanen, T. Virtanen, P. Raunio, 1998, Allergy.

Potential of an altered peptide ligand of lipocalin allergen Bos d 2 for peptide immunotherapy.

A. Närvänen, W. Kwok, T. Kinnunen, 2007, The Journal of allergy and clinical immunology.

T Cell Epitope-Containing Peptides of the Major Dog Allergen Can f 1 as Candidates for Allergen Immunotherapy

J. Partanen, B. Maillère, A. Närvänen, 2005 .

Threshold levels of purified natural Bos d 2 for inducing bronchial airway response in asthmatic patients

R. Mäntyjärvi, H. Tukiainen, T. Zeiler, 2002, Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology.

Nasal sensitization of dairy farmers to bovine epithelial and urinary antigens.

R. Mäntyjärvi, J. Nuutinen, M. Rautiainen, 1992, Rhinology.

IgG and IgE antibody responses to cow dander and urine in farmers with cow‐induced asthma

R. Mäntyjärvi, T. Virtanen, A. Taivainen, 1992, Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology.

Concentrations of specific dusts in swineries and the humoral response of swinery workers

R. Mäntyjärvi, P. Kalliokoski, T. Virtanen, 1990, Allergy.

Comparative analysis of bovine extracts by immunoblotting and ELISA inhibition

R. Mäntyjärvi, J. Nuutinen, T. Virtanen, 1990, Allergy.

Enzyme-linked immunosorbent assay (ELISA) inhibition method to estimate the level of airborne bovine epidermal antigen in cowsheds.

K. Louhelainen, R. Mäntyjärvi, T. Virtanen, 1986, International Archives of Allergy and Applied Immunology.

Mammalian lipocalin allergens – insights into their enigmatic allergenicity

T. Kinnunen, T. Virtanen, M. Rytkönen-Nissinen, 2012, Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology.

The DR4–DQ8 haplotype and a specific T cell receptor Vβ T cell subset are associated with absence of allergy to Can f 1

J. Partanen, T. Kinnunen, T. Virtanen, 2005, Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology.

Probing the mechanisms of low immunogenicity of a lipocalin allergen, Bos d 2, in a mouse model

R. Mäntyjärvi, T. Kinnunen, T. Virtanen, 2003, Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology.

Lipocalin allergen Bos d 2 is a weak immunogen.

A. Närvänen, P. Vilja, R. Mäntyjärvi, 2002, International immunology.

Use of multiple peptides containing T cell epitopes is a feasible approach for peptide‐based immunotherapy in Can f 1 allergy

A. Närvänen, T. Kinnunen, T. Virtanen, 2007, Immunology.

Recombinant allergen fragments as candidate preparations for allergen immunotherapy.

H. Karjalainen, L. Tuomisto, R. Mäntyjärvi, 1997, The Journal of allergy and clinical immunology.

Psoriasin, a calcium-binding protein with chemotactic properties is present in the third trimester amniotic fluid.

R. Mäntyjärvi, T. Virtanen, J. Rautiainen, 2005, Molecular human reproduction.

Differential CD4+ T‐cell responses of allergic and non‐allergic subjects to the immunodominant epitope region of the horse major allergen Equ c 1

W. Kwok, T. Kinnunen, T. Virtanen, 2014, Immunology.

Comparison of the allergic and nonallergic CD4+ T-cell responses to the major dog allergen Can f 1.

S. Parviainen, T. Kinnunen, T. Virtanen, 2010, The Journal of allergy and clinical immunology.

In vitro and in vivo responses to the recombinant bovine dander allergen Bos d 2 and its fragments

J. Nuutinen, T. Zeiler, T. Virtanen, 2001, Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology.

Human memory CD4+ T cell response to the major dog allergen Can f 5, prostatic kallikrein

J. Lidholm, L. Mattsson, T. Kinnunen, 2016, Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology.

Mapping of human T-cell epitopes of allergens.

T. Zeiler, T. Virtanen, 2008, Methods in molecular medicine.

Mammal‐Derived Respiratory Lipocalin Allergens do not Exhibit Dendritic Cell‐Activating Capacity

S. Parviainen, T. Kinnunen, T. Virtanen, 2013, Scandinavian journal of immunology.

No relationship between skin-infiltrating TH2-like cells and allergen-specific IgE response in atopic dermatitis.

M. de Carli, R. Manetti, M. Piccinni, 1995, The Journal of allergy and clinical immunology.

Search for the determinants of allergenicity in proteins of the lipocalin family.

J. Rouvinen, R. Mäntyjärvi, T. Virtanen, 2001, Journal of chromatography. B, Biomedical sciences and applications.

Tissue localization of bovine dander allergen Bos d 2.

K. Syrjänen, R. Mäntyjärvi, M. Rytkönen, 1998, The Journal of allergy and clinical immunology.

Assessment of recombinant dog allergens Can f 1 and Can f 2 for the diagnosis of dog allergy

S. Auriola, R. Mäntyjärvi, T. Kinnunen, 2004, Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology.

Commentary: Allergen and Epitope Targets of Mouse-Specific T Cell Responses in Allergy and Asthma

T. Virtanen, M. Rytkönen-Nissinen, 2019, Front. Immunol..

The immunodominant epitope of lipocalin allergen Bos d 2 is suboptimal for human T cells.

B. Maillère, A. Närvänen, R. Mäntyjärvi, 2003, European journal of immunology.

Complementary DNA cloning of the predominant allergen of bovine dander: a new member in the lipocalin family.

J. Pelkonen, R. Mäntyjärvi, M. Rytkönen, 1996, The Journal of allergy and clinical immunology.

cDNA cloning and protein analysis of a bovine dermal allergen with homology to psoriasin.

J. Pelkonen, R. Mäntyjärvi, M. Rytkönen, 1995, The Journal of investigative dermatology.

Preliminary description of antigenic components characteristic of Stachybotrys chartarum.

A. Pasanen, M. Kärkkäinen, T. Virtanen, 2001, Environmental research.

IgE Reactivity of the Dog Lipocalin Allergen Can f 4 and the Development of a Sandwich ELISA for Its Quantification

N. Kalkkinen, T. Virtanen, S. Saarelainen, 2015, Allergy, asthma & immunology research.

Animal‐derived lipocalin allergens exhibit immunoglobulin E cross‐reactivity

J. Rouvinen, A. Kauppinen, S. Auriola, 2007, Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology.

Affinity purification of the major bovine allergen by a novel monoclonal antibody.

J. Pelkonen, R. Mäntyjärvi, T. Virtanen, 1994, The Journal of allergy and clinical immunology.

Comparison of the antigenic and allergenic properties of three types of bovine epithelial material.

R. Mäntyjärvi, T. Virtanen, A. Taivainen, 1992, International archives of allergy and immunology.

Immune reactivity of cow‐asthmatic dairy farmers to the major allergen of cow (BDA20) and to other cow‐derived proteins. The use of purified BDA20 increases the performance of diagnostic tests in respiratory cow allergy

J. Pelkonen, R. Mäntyjärvi, M. Rytkönen, 1996, Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology.

Inhalant Mammal-Derived Lipocalin Allergens and the Innate Immunity

T. Virtanen, 2022, Frontiers in Allergy.

Characterization of human memory CD4(+) T-cell responses to the dog allergen Can f 4.

B. Maillère, T. Kinnunen, T. Virtanen, 2015, The Journal of allergy and clinical immunology.

T Cell Epitope-Containing Peptides of the Major Dog Allergen Can f 1 as Candidates for Allergen Immunotherapy1

Jukka Partanen, Ale Närvänen, Bernard Maillere, 2005, The Journal of Immunology.

Not all proteins are created allergens.

T. Kinnunen, T. Virtanen, 2007, The Journal of allergy and clinical immunology.

Mammalian allergens.

T. Virtanen, R. Järvi, 2004, Clinical allergy and immunology.

The major horse allergen Equ c 1 contains one immunodominant region of T cell epitopes

D. Houitte, B. Maillère, A. Närvänen, 2007, Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology.

Dimerization of lipocalin allergens

J. Jänis, J. Rouvinen, T. Virtanen, 2015, Scientific Reports.

A bovine dander allergen, comparative modeling, and similarities and differences in folding with related proteins

R. Laatikainen, R. Mäntyjärvi, H. Santa, 1998, Journal of protein chemistry.

Adaptive immunity as a determinant of allergenicity.

T. Kinnunen, T. Virtanen, 2009, The Journal of allergy and clinical immunology.

EFFECTS OF AEROSOLS FROM NONTOXIC Stachybotrys chartarum ON MURINE AIRWAYS

V. Kosma, A. Pasanen, T. Virtanen, 2002, Inhalation toxicology.

Quantification of a major bovine allergen by a two‐site immunometric assay based on monoclonal antibodies

R. Mäntyjärvi, M. Rytkönen, T. Virtanen, 1994, Allergy.

Probing the Molecular Basis of Allergy

J. Rouvinen, R. Mäntyjärvi, J. Kauppinen, 1999, The Journal of Biological Chemistry.

Molecular and crystal properties of Bos d 2, an allergenic protein of the lipocalin family.

J. Rouvinen, S. Auriola, R. Mäntyjärvi, 1998, Biochemical and biophysical research communications.

Airborne Allergens and Their Quantification and Effect on the Development of Allergy in Occupational Environments

Tuomas Virtanen, R. Mäntyjärvi, R. Mäntyjärvi, 1994 .

Structural aspects of dog allergies: the crystal structure of a dog dander allergen Can f 4.

J. Jänis, J. Rouvinen, T. Virtanen, 2014, Molecular immunology.

Molecular analysis of allergenic proteins in bovine dander

J. Pelkonen, R. Mäntyjärvi, M. Rytkönen, 1996, Allergy.

Reply to the letter to the editor concerning the review Immunotherapy for pet allergies

T. Virtanen, 2018, Human vaccines & immunotherapeutics.

Homology of a bovine allergen and the oligomycin sensitivity-conferring protein of the mitochondrial adenosine triphosphate synthase complex.

R. Mäntyjärvi, M. Rytkönen, J. Pentikäinen, 1995, Journal of Allergy and Clinical Immunology.

Detection of airborne reindeer epithelial antigen by enzyme‐linked immunosorbent assay inhibition

K. Reijula, J. Hassi, R. Mäntyjärvi, 1992, Allergy.

The immunodominant epitope of lipocalin allergen Bos d 2 is suboptimal for human T cells

B. Maillère, R. Mäntyjärvi, T. Kinnunen, 2003 .

Long- and short-term variability of airborne bovine epithelial antigen concentrations in cowsheds.

K. Husman, R. Mäntyjärvi, T. Virtanen, 1992, International Archives of Allergy and Immunology.

Humoral responses to bovine dust in dairy farmers with allergic rhinitis.

M Rautiainen, R. Mäntyjärvi, T Virtanen, 1997, Acta oto-laryngologica. Supplementum.

BDA20, a major bovine dander allergen characterized at the sequence level, is Bos d 2.

R. Mäntyjärvi, M. Rytkönen, J. Pentikäinen, 1997, The Journal of allergy and clinical immunology.

Two ELISA methods for the measurement of airborne swine epithelial antigens.

T. Virtanen, 1990, Journal of immunoassay.

Allergen‐specific naïve and memory CD4+ T cells exhibit functional and phenotypic differences between individuals with or without allergy

W. Kwok, T. Kinnunen, T. Virtanen, 2010, European journal of immunology.