Y. Gao

发表

N-omega-fluoroalkyl analogs of (1R)-2 beta-carbomethoxy-3 beta-(4-iodophenyl)-tropane (beta-CIT): radiotracers for positron emission tomography and single photon emission computed tomography imaging of dopamine transporters.

R. Baldessarini, R. Innis, R. Baldwin, 1994, Journal of medicinal chemistry.

N-terminal carboxyl and tetrazole-containing amides as adjuvants to Grb2 SH2 domain ligand binding.

T. Burke, Z. Yao, X. Zhu, 2001, Bioorganic & medicinal chemistry.

Macrocyclization in the design of a conformationally constrained Grb2 SH2 domain inhibitor.

T. Burke, J. Voigt, D. Yang, 2001, Bioorganic & medicinal chemistry letters.

Stereoisomeric, Photoaffinity, Affinity and Fluorescent Probes for Characterization of Dopamine D1 and D2 Receptors

R. Baldessarini, J. Neumeyer, Y. Gao, 1992 .

Modeling directed design and biological evaluation of quinazolinones as non-peptidic growth hormone secretagogues.

A. Howard, S. Feighner, S. Pong, 2000, Bioorganic & Medicinal Chemistry Letters.

R(−)2-fluoro-n-n-propylnorapomorphine: A very potent and D2-selective dopamine agonist

A. Campbell, R. Baldessarini, J. Neumeyer, 1991, Neuropharmacology.

Inhibition of Grb2 SH2 domain binding by non-phosphate-containing ligands. 2. 4-(2-Malonyl)phenylalanine as a potent phosphotyrosyl mimetic.

T. Burke, Z. Yao, J. Voigt, 2000, Journal of medicinal chemistry.

Monocarboxylic-based phosphotyrosyl mimetics in the design of GRB2 SH2 domain inhibitors.

G. Milne, T. Burke, H. Zhao, 1999, Bioorganic & medicinal chemistry letters.

Use of a Heck reaction for the synthesis of a new alpha-azido phosphotyrosyl mimetic suitably protected for peptide synthesis.

T. Burke, Y. Gao, D. Liu, 2000, The Journal of organic chemistry.

Utilization of a peptide lead for the discovery of a novel PTP1B-binding motif.

L. Wu, T. Burke, Z. Zhang, 2001, Journal of medicinal chemistry.

Synthesis and dopamine receptor affinities of enantiomers of 2-substituted apomorphines and their N-n-propyl analogues.

R. Baldessarini, J. Neumeyer, R J Baldessarini, 1990, Journal of medicinal chemistry.

2 beta-substituted analogues of cocaine. Synthesis and inhibition of binding to the cocaine receptor.

M. Kuhar, F. Carroll, A. Lewin, 1992, Journal of medicinal chemistry.

N-Substituted Analogues of 2β-Carbomethoxy-3β-(4′-iodophenyl) tropane (β-CIT) with Selective Affinity to Dopamine or Serotonin Transporters in Rat Forebrain.

R. Baldessarini, J. Neumeyer, G. Tamagnan, 1996 .

Synthesis, ligand binding, and QSAR (CoMFA and classical) study of 3 beta-(3'-substituted phenyl)-, 3 beta-(4'-substituted phenyl)-, and 3 beta-(3',4'-disubstituted phenyl)tropane-2 beta-carboxylic acid methyl esters.

F I Carroll, P Abraham, S W Mascarella, 1994, Journal of medicinal chemistry.

Probes for the cocaine receptor. Potentially irreversible ligands for the dopamine transporter.

M. Kuhar, R. Lew, F. Carroll, 1992, Journal of medicinal chemistry.

Synthesis, ligand binding, QSAR, and CoMFA study of 3 beta-(p-substituted phenyl)tropane-2 beta-carboxylic acid methyl esters.

F I Carroll, P Abraham, M. Kuhar, 1991, Journal of medicinal chemistry.

Phosphoryltyrosyl mimetics in the design of peptide-based signal transduction inhibitors.

T. Burke, Z. Yao, J. Voigt, 2001, Biopolymers.

Neuropharmacology and stereochemistry of dopamine receptor agonist and antagonist enantiomeric pairs.

A. Campbell, R. Baldessarini, M. Froimowitz, 1988, Journal of receptor research.

Effects of isomers of hydroxyaporphines on dopamine metabolism in rat brain regions.

Eric R. Marsh, R. Baldessarini, J. Neumeyer, 1990, Biochemical pharmacology.

R(−) and s(+) stereoisomers of 11-hydroxy- and 11 -methoxy-N-n -propylnoraporphine: Central dopaminergic behavioral activity in the rat

A. Campbell, R. Baldessarini, J. Neumeyer, 1990, Neuropharmacology.

Quinoline-4-acetamides as sPLA(2) inhibitors.

Y. Gao, R. Wang, Y. Feng, 2001, Bioorganic & medicinal chemistry letters.

Synthesis and structural requirements of N-substituted norapomorphines for affinity and activity at dopamine D-1, D-2, and agonist receptor sites in rat brain.

R. Baldessarini, J. Neumeyer, V. Ram, 1990, Journal of medicinal chemistry.

Synthesis and dopamine receptor affinity of (R)-(-)-2-fluoro-N-n-propylnorapomorphine: a highly potent and selective dopamine D2 agonist.

R. Baldessarini, J. Neumeyer, R J Baldessarini, 1990, Journal of medicinal chemistry.

Presynaptic inhibition of dopamine synthesis in rat striatal tissue by enantiomeric mono- and dihydroxyaporphines.

R. Baldessarini, J. Neumeyer, R. Booth, 1990, Molecular pharmacology.

N-substituted analogs of 2 beta-carbomethoxy-3 beta- (4'-iodophenyl)tropane (beta-CIT) with selective affinity to dopamine or serotonin transporters in rat forebrain.

R. Baldessarini, J. Neumeyer, S. Wang, 1996, Journal of medicinal chemistry.

Synthesis and dopamine agonist and antagonist effects of (R)-(-)- and (S)-(+)-11-hydroxy-N-n-propylnoraporphine.

R. Baldessarini, J. Neumeyer, A. Campbell, 1988, Journal of medicinal chemistry.

R and S enantiomers of 11-hydroxy- and 10,11-dihydroxy-N-allylnoraporphine: synthesis and affinity for dopamine receptors in rat brain tissue.

R. Baldessarini, J. Neumeyer, Y. Gao, 1991, Journal of medicinal chemistry.

Olefin metathesis in the design and synthesis of a globally constrained Grb2 SH2 domain inhibitor.

T. Burke, Y. Gao, C. Wei, 2001, Organic Letters.