N. Kula

发表

N-omega-fluoroalkyl analogs of (1R)-2 beta-carbomethoxy-3 beta-(4-iodophenyl)-tropane (beta-CIT): radiotracers for positron emission tomography and single photon emission computed tomography imaging of dopamine transporters.

R. Baldessarini, R. Innis, R. Baldwin, 1994, Journal of medicinal chemistry.

[3H]β-CIT: a radioligand for dopamine transporters in rat brain tissue

F. Tarazi, R. Baldessarini, J. Neumeyer, 1999 .

[3H]beta-CIT: a radioligand for dopamine transporters in rat brain tissue.

F. Tarazi, R. Baldessarini, J. Neumeyer, 1999, European journal of pharmacology.

Effects of dietary fat on hepatic mixed-function oxidases and hepatocellular carcinoma induced by aflatoxin B1 in rats.

P. Newberne, J. Weigert, N. Kula, 1979, Cancer research.

Lack of increase in dopamine transporter binding or function in rat brain tissue after treatment with blockers of neuronal uptake of dopamine

R. Baldessarini, N. Kula, 1991, Neuropharmacology.

Effects of alkylating agents on dopamine D3 receptors in rat brain: selective protection by dopamine

F. Tarazi, R. Baldessarini, N. Weiss, 1999, Brain Research.

Effects of N-substituted phenyltetrahydropyridines on cerebral high-affinity synaptosomal uptake of dopamine and other monoamines in several mammalian species.

S. Finklestein, R. Baldessarini, J. Neumeyer, 1984, Life sciences.

Behavioral effects of apomorphine and diisobutyrylapomorphine in the mouse

R. Baldessarini, N. Kula, K. Walton, 1977, Psychopharmacology.

Hydrolysis of diester prodrugs of apomorphine.

R. Baldessarini, N. Kula, K. Walton, 1977, Biochemical pharmacology.

Substituted phenylpiperidines and phenylpyridines as reversible selective inhibitors of monoamine oxidase type A in rodent brain and liver.

R. Baldessarini, J. Neumeyer, N. Kula, 1988, Biochemical pharmacology.

N-Substituted Analogs of 2β-Carbomethoxy-3β-(4‘-iodophenyl)tropane (β-CIT) with Selective Affinity to Dopamine or Serotonin Transporters in Rat Forebrain

R. Baldessarini, J. Neumeyer, G. Tamagnan, 1996 .

Antioxidants fail to inhibit depletion of striatal dopamine by MPTP

S. Finklestein, R. Baldessarini, N. Kula, 1986, Neurology.

Synthetic analgesics and other phenylpiperidines: effects on uptake and storage of dopamine and other monoamines mouse forebrain tissue.

S. Finklestein, R. Baldessarini, J. Neumeyer, 1986, Life sciences.

Fatty Acid Derivatives of Clozapine: Prolonged Antidopaminergic Activity of Docosahexaenoylclozapine in the Rat

A. Campbell, R. Baldessarini, M. O. Bradley, 2001, Neuropsychopharmacology.

Oral bioavailability of apomorphine in the rat with a portacaval venous anastomosis.

A. Campbell, R. Baldessarini, B. Jeppsson, 1980, European journal of pharmacology.

Neuropharmacological assessment of potential dopamine D4 receptor-selective radioligands.

F. Tarazi, R. Baldessarini, N. Kula, 1999, European journal of pharmacology.

Stereoisomeric, Photoaffinity, Affinity and Fluorescent Probes for Characterization of Dopamine D1 and D2 Receptors

R. Baldessarini, J. Neumeyer, Y. Gao, 1992 .

Distribution of Fluphenazine and Its Metabolites in Brain Regions and Other Tissues of the Rat

R. Baldessarini, S. Marder, M. Aravagiri, 1995, Neuropsychopharmacology.

Synthesis and amine transporter affinities of novel phenyltropane derivatives as potential positron emission tomography (PET) imaging agents.

R. Baldessarini, A. Zhang, J. Neumeyer, 2004, Bioorganic & medicinal chemistry letters.

Novel Phenyltropanes: Affinity to Monoamine Transporters in Rat Forebrain

R. Baldessarini, J. Neumeyer, G. Tamagnan, 1998 .

Pharmacology of binding of 3H-SCH-23390 to D-1 dopaminergic receptor sites in rat striatal tissue.

R. Baldessarini, G. Faedda, N. Kula, 1989, Biochemical pharmacology.

Selective alkylatation of dopamine D2 and D4 receptors in rat brain by N-(p-isothiocyanatophenethyl)spiperone

F. Tarazi, R. Baldessarini, J. Neumeyer, 1999, Neuroscience Letters.

Receptor affinities of aporphine enantiomers in rat brain tissue.

R. Baldessarini, J. Neumeyer, N. Kula, 1994, European journal of pharmacology.

R(−)2-fluoro-n-n-propylnorapomorphine: A very potent and D2-selective dopamine agonist

A. Campbell, R. Baldessarini, J. Neumeyer, 1991, Neuropharmacology.

S-(+)-aporphines are not selective for human D3 dopamine receptors

J. Kebabian, R. Baldessarini, J. Neumeyer, 1994, Cellular and Molecular Neurobiology.

Isomeric selectivity at dopamine D3 receptors.

J. Kebabian, R. Baldessarini, J. Neumeyer, 1993, European journal of pharmacology.

Receptor affinities of dopamine D1 receptor-selective novel phenylbenzazepines.

R. Baldessarini, J. Neumeyer, J. Bergman, 2003, European Journal of Pharmacology.

New sigma-like receptor recognized by novel phenylaminotetralins: ligand binding and functional studies.

A. M. Myers, R. Mailman, R. Baldessarini, 1993, Molecular pharmacology.

Interactions of fluoxetine with metabolism of dopamine and serotonin in rat brain regions

Eric R. Marsh, R. Baldessarini, N. Kula, 1992, Brain Research.

Prolonged D2 antidopaminergic activity of alkylating and nonalkylating derivatives of spiperone in rat brain.

R. Baldessarini, J. Yuan, J. Neumeyer, 1992, Molecular pharmacology.

Selective probes for characterization of dopamine D1 and D2 receptors

R. Baldessarini, J. Neumeyer, B. Madras, 1992, Neurochemistry International.

Synthesis, receptor potency, and selectivity of halogenated diphenylpiperidines as serotonin 5-HT2A ligands for PET or SPECT brain imaging.

R. Baldessarini, R. Innis, R. Baldwin, 2002, Journal of medicinal chemistry.

Stereoisomeric probes for the D1 dopamine receptor: synthesis and characterization of R-(+) and S-(-) enantiomers of 3-allyl-7,8-dihydroxy-1-phenyl-2,3,4,5-tetrahydro-1H-3-benzazepine and its 6-bromo analogue.

R. Baldessarini, J. Neumeyer, N. Kula, 1992, Journal of medicinal chemistry.

Long-Term Effects of S(+)N-n-Propylnorapomorphine Compared with Typical and Atypical Antipsychotics: Differential Increases of Cerebrocortical D2-Like and Striatolimbic D4-Like Dopamine Receptors

F. Tarazi, S. Yeghiayan, R. Baldessarini, 1997, Neuropsychopharmacology.

Synthesis and neuropharmacological evaluation of R(-)-N-alkyl-11-hydroxynoraporphines and their esters.

R. Baldessarini, A. Zhang, J. Neumeyer, 2004, Bioorganic & medicinal chemistry.

Synthesis and dopamine receptor affinities of enantiomers of 2-substituted apomorphines and their N-n-propyl analogues.

R. Baldessarini, J. Neumeyer, R J Baldessarini, 1990, Journal of medicinal chemistry.

Absence of an effect of partial hepatectomy on aflatoxin B 1 carcinogenesis.

A. E. Rogers, P. Newberne, N. Kula, 1971, Cancer research.

Synthesis and monoamine transporter affinity of 2β-carbomethoxy-3β-(4′- p -substituted phenyl)-piperidine analogs of cocaine

R. Baldessarini, R. Innis, R. Baldwin, 2006 .

N-Substituted Analogues of 2β-Carbomethoxy-3β-(4′-iodophenyl) tropane (β-CIT) with Selective Affinity to Dopamine or Serotonin Transporters in Rat Forebrain.

R. Baldessarini, J. Neumeyer, G. Tamagnan, 1996 .

Prolonged decrease of serum prolactin in rat by an ester prodrug of apomorphine

R. Baldessarini, A. E. Boyd, N. Kula, 1979, Psychoneuroendocrinology.

Effects of Dietary Fat on Hepatic Mixed-Function Oxidases and Hepatocellular Carcinoma Induced by Aflatoxin B 1 in Rats 1

P. Newberne, J. Weigert, N. Kula, 2006 .

Regional distribution of dopamine D4 receptors in rat forebrain

F. Tarazi, R. Baldessarini, N. Kula, 1997, Neuroreport.

Clozapine Withdrawal: Serotonergic or Dopaminergic Mechanisms?-Reply

F. Tarazi, R. Baldessarini, D. Gardner, 1997 .

Compounds selective for dopamine receptor subtypes

J. Kebabian, F. Tarazi, R. Baldessarini, 1997 .

Long-Term Effects of Olanzapine, Risperidone, and Quetiapine on Ionotropic Glutamate Receptor Types: Implications for Antipsychotic Drug Treatment

F. Tarazi, R. Baldessarini, N. Kula, 2003, Journal of Pharmacology and Experimental Therapeutics.

Synthesis and pharmacological evaluation of 1-phenyl-3-amino-1,2,3,4-tetrahydronaphthalenes as ligands for a novel receptor with sigma-like neuromodulatory activity.

A. M. Myers, R. Mailman, R. Baldessarini, 1993, Journal of medicinal chemistry.

RBI-257: a highly potent dopamine D4 receptor-selective ligand.

J. Kebabian, R. Baldessarini, N. Kula, 1997, European journal of pharmacology.

Synthesis and monoamine transporter affinity of 2β-carbomethoxy-3β-(2″-, 3″- or 4″-substituted) biphenyltropanes

R. Baldessarini, R. Innis, R. Baldwin, 2000 .

Irreversible binding of [3H](-)N-chloroethylnorapomorphine to mammalian brain tissue.

R. Baldessarini, N. Kula, 1983, Life sciences.

Chloroethylnorapomorphine, a proposed long-acting dopamine antagonist: interactions with dopamine receptors of mammalian forebrain in vitro.

R. Baldessarini, G. Arana, J. Neumeyer, 1980, European journal of pharmacology.

Receptor affinity, neurochemistry and behavioral characteristics of the enantiomers of thioridazine: Evidence for different stereoselectivities at D1 and D2 receptors in rat brain

B. Cohen, A. Campbell, R. Baldessarini, 1988, Neuropharmacology.

Vascular damage and lipid peroxidation in choline-deficient rats.

P. Newberne, M. W. Conner, N. Kula, 1973, Experimental and molecular pathology.

Alkylation of rat dopamine transporters and blockade of dopamine uptake by EEDQ

F. Tarazi, R. Baldessarini, N. Kula, 2000, Neuropharmacology.

Synthesis and biological evaluation of a series of novel N- or O-fluoroalkyl derivatives of tropane: potential positron emission tomography (PET) imaging agents for the dopamine transporter.

R. Baldessarini, J. Neumeyer, N. Kula, 2001, Bioorganic & medicinal chemistry letters.

Effects of norepinephrine and serotonin transporter inhibitors on hyperactivity induced by neonatal 6-hydroxydopamine lesioning in rats.

F. Tarazi, R. Baldessarini, N. Kula, 2002, The Journal of pharmacology and experimental therapeutics.

Plasma levels of apomorphine following intravenous, intraperitoneal and oral administration to mice and rats.

R. Baldessarini, R. Wilcox, W. Soine, 1979, Research communications in chemical pathology and pharmacology.

Determination of N-n-propylnorapomorphine in serum and brain tissue by gas chromatography-negative ion chemical ionization mass spectrometry.

R. Baldessarini, P. Lampen, J. Neumeyer, 1988, Journal of chromatography.

S(+)methylenedioxy-N-n-propylnoraporphine: an orally active inhibitor of dopamine selective for rat limbic system

A. Campbell, R. Baldessarini, J. Neumeyer, 1987, Brain Research.

An orally effective, long-acting dopaminergic prodrug: (-)-10,11-methylenedioxy-N-propylnoraporphine.

R. Baldessarini, G. Sperk, G. Arana, 1982, European journal of pharmacology.

Differential effects of ascorbate and EDTA on high-affinity binding of 3H-apomorphine and 3H-ADTN to calf caudate membranes

R. Baldessarini, G. Arana, N. Kula, 1982, Neuropharmacology.

Effects of cations on high-affinity binding of 3H-ADTN to dopaminergic sites in calf caudate tissue

R. Baldessarini, N. Kula, J. Lamont, 1987, Neuropharmacology.

Effects of isomers of apomorphines on dopamine receptors in striatal and limbic tissue of rat brain.

R. Baldessarini, J. Neumeyer, N. Kula, 1985, Life sciences.

Aporphines. 48. Enantioselectivity of (R)-(-)- and (S)-(+)-N-n-propylnorapomorphine on dopamine receptors.

R. Baldessarini, G. Arana, J. Neumeyer, 1983, Journal of Medicinal Chemistry.

Aporphines. 39. Synthesis, dopamine receptor binding, and pharmacological activity of (R)-(-)- and (S)-(+)-2-hydroxyapomorphine.

R. Baldessarini, G. Arana, J. Neumeyer, 1982, Journal of Medicinal Chemistry.

Effects of isomers of hydroxyaporphines on dopamine metabolism in rat brain regions.

Eric R. Marsh, R. Baldessarini, J. Neumeyer, 1990, Biochemical pharmacology.

Effects of alternative transmitter amines on cyclic AMP formation in rat brain tissue.

R. Baldessarini, N. Kula, K. Walton, 1979, European journal of pharmacology.

APORPHINES. 48. ENANTIOSELECTIVITY OF (R)-(-)- AND (S)-(+)-N-N-PROPYLNORAPOMORPHINE ON DOPAMINE RECEPTORS

R. Baldessarini, G. Arana, J. Neumeyer, 1983 .

APORPHINES. 39. SYNTHESIS, DOPAMINE RECEPTOR BINDING, AND PHARMACOLOGICAL ACTIVITY OF (R)-(-)- AND (S)-(+)-2-HYDROXYAPOMORPHINE

R. Baldessarini, G. Arana, J. Neumeyer, 1983 .

Rate of recovery of D1 and D2 dopaminergic receptors in young vs. adult rat striatal tissue following alkylation with ethoxycarbonyl-ethoxy-dihydroquinoline (EEDQ).

R. Baldessarini, N. Kula, T. George, 1992, Brain research. Developmental brain research.

Synthesis and monoamine transporter affinity of new 2β-carbomethoxy-3β-[aryl or heteroaryl]phenyltropanes

R. Baldessarini, R. Innis, R. Baldwin, 2006 .

Effects of two synthetic antioxidants, vitamin E, and ascorbic acid on the choline-deficient rat.

P. Newberne, N. Kula, M. Bresnahan, 1969, The Journal of nutrition.

Synthesis and structural requirements of N-substituted norapomorphines for affinity and activity at dopamine D-1, D-2, and agonist receptor sites in rat brain.

R. Baldessarini, J. Neumeyer, V. Ram, 1990, Journal of medicinal chemistry.

Synthesis and dopamine receptor affinity of (R)-(-)-2-fluoro-N-n-propylnorapomorphine: a highly potent and selective dopamine D2 agonist.

R. Baldessarini, J. Neumeyer, R J Baldessarini, 1990, Journal of medicinal chemistry.

Presynaptic inhibition of dopamine synthesis in rat striatal tissue by enantiomeric mono- and dihydroxyaporphines.

R. Baldessarini, J. Neumeyer, R. Booth, 1990, Molecular pharmacology.

Synthesis, radiolabeling and baboon SPECT imaging of 2β-carbomethoxy-3β-(3′-[123I]iodophenyl)tropane ([123I]YP256) as a serotonin transporter radiotracer

R. Baldessarini, J. Staley, R. Innis, 2008 .

N-substituted analogs of 2 beta-carbomethoxy-3 beta- (4'-iodophenyl)tropane (beta-CIT) with selective affinity to dopamine or serotonin transporters in rat forebrain.

R. Baldessarini, J. Neumeyer, S. Wang, 1996, Journal of medicinal chemistry.

Bromocriptine antagonizes behavioral effects of cocaine in the rat.

Martin H. Teicher, A. Campbell, R. Baldessarini, 1989, Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology.

Role of Dopamine in Behavioral Effects of Serotonin Microinjected into Rat Striatum

A. Kelley, A. Campbell, S. Yeghiayan, 1997, Pharmacology Biochemistry and Behavior.

Conformational analysis, pharmacophore identification, and comparative molecular field analysis of ligands for the neuromodulatory sigma 3 receptor.

A. M. Myers, R. Baldessarini, P. Charifson, 1994, Journal of medicinal chemistry.

Synthesis and dopamine receptor binding of sulfur-containing aporphines.

R. Baldessarini, J. Neumeyer, M. Tóth, 2006, Bioorganic & medicinal chemistry.

Synthesis and dopamine agonist and antagonist effects of (R)-(-)- and (S)-(+)-11-hydroxy-N-n-propylnoraporphine.

R. Baldessarini, J. Neumeyer, A. Campbell, 1988, Journal of medicinal chemistry.

Stereochemical Effects of Mono‐ and Dihydroxyaporphines on Presynaptic Inhibition of Dopamine Synthesis In Vitro a

R. Baldessarini, J. Neumeyer, R. Booth, 1990 .

R and S enantiomers of 11-hydroxy- and 10,11-dihydroxy-N-allylnoraporphine: synthesis and affinity for dopamine receptors in rat brain tissue.

R. Baldessarini, J. Neumeyer, Y. Gao, 1991, Journal of medicinal chemistry.

R‐ and S‐Enantiomers of 11‐Hydroxy‐ (Ia) and 10,11‐Dihydroxy‐N‐ allylnoraporphine (Ib): Synthesis and Affinity for Dopamine Receptors in Rat Brain Tissue.

R. Baldessarini, J. Neumeyer, N. Kula, 1991 .

N‐Monofluoroalkylnoraporphines: Synthesis and Binding Dopamine Receptor Studies.

R. Baldessarini, J. Neumeyer, N. Kula, 1993 .

APORPHINES. 30. (-)-N-(2-CHLOROETHYL)-10,11-DIHYDROXYNORAPORPHINE (CHLOROETHYLNORAPOMORPHINE), NOVEL IRREVERSIBLE DOPAMINE RECEPTOR ANTAGONIST

R. Baldessarini, J. Neumeyer, S. Law, 1980 .

Aporphines. 30. (-)-N(2-chloroethyl)-10,11-dihydroxynor-aporphine (chloroethylnorapomorphine), a novel irreversible dopamine receptor antagonist.

R. Baldessarini, J. Neumeyer, S. Law, 1980, Journal of medicinal chemistry.

Cyclopentadienyltricarbonylrheniumbenzazepines: synthesis and binding affinity.

R. Baldessarini, R. Innis, R. Baldwin, 2000, Bioorganic & medicinal chemistry letters.

Effects of norepinephrine and serotonin transporter inhibitors on hyperactivity induced by neonatal 6-hydroxydopamine lesioning in rats.

F. Tarazi, R. Baldessarini, N. Kula, 2002, The Journal of pharmacology and experimental therapeutics.

Prolonged antidopaminergic actions of single doses of butyrophenones in the rat

Martin H. Teicher, A. Campbell, R. Baldessarini, 1985, Psychopharmacology.