A. Leone

发表

An ionic liquid form of DNA: redox-active molten salts of nucleic acids.

R. Murray, M. Williams, H. Thorp, 2001, Journal of the American Chemical Society.

Solid-State Spectroscopic Investigation of Molecular Interactions between Clofazimine and Hypromellose Phthalate in Amorphous Solid Dispersions.

Mingtao Zhang, S. Byrn, L. S. Taylor, 2016, Molecular pharmaceutics.

Polydispersity characterization of lipid nanoparticles for siRNA delivery using multiple detection size-exclusion chromatography.

Jingtao Zhang, A. Leone, R. M. Haas, 2012, Analytical chemistry.

Enhancing Host-Cell Protein Detection in Protein Therapeutics Using HILIC Enrichment and Proteomic Analysis.

Thomas R. Slaney, Wei Wu, R. Ludwig, 2020, Analytical chemistry.

Subunit mass analysis for monitoring multiple attributes of monoclonal antibodies.

Wei Wu, Hangtian Song, R. Ludwig, 2018, Rapid communications in mass spectrometry : RCM.

Counterion diffusivity measurements support ion atmosphere relaxation control of electron transfer rates in a semi-solid ruthenium complex molten salt

R. Murray, Wei Wang, Dongil Lee, 2005 .

Chemistry of a high-oxidation-level manganese porphyrin in aqueous solution

M. Calvin, J. Otvos, L. O. Spreer, 1988 .

Ion atmosphere relaxation and percolative electron transfer in Co bipyridine DNA molten salts.

R. Murray, S. Feldberg, H. Thorp, 2003, Journal of the American Chemical Society.

New and Evolving Techniques for the Characterization of Peptide Therapeutics.

Yun Mao, Suzanne M D'Addio, Jameson R Bothe, 2016, Journal of pharmaceutical sciences.

In Situ Characterization of Pharmaceutical Formulations by Dynamic Nuclear Polarization Enhanced MAS NMR.

R. Griffin, R. Williamson, I. Sergeyev, 2017, The journal of physical chemistry. B.

Electrodeposition and Electrochemical Behavior of Palladium Particles at Polyaniline and Polypyrrole Films

B. Scharifker, A. Leone, W. Marino, 1992 .

Mechanism and Impact of Excipient Incompatibility: Crosslinking of Xanthan Gum in Pediatric Powder-for-suspension Formulations.

A. Templeton, Allen C. Templeton, X. Jia, 2019, Journal of pharmaceutical sciences.

Challenges in the pharmaceutical development of lipid-based short interfering ribonucleic acid therapeutics

Marian E. Gindy, James J. Cunningham, A. Leone, 2012, Expert opinion on drug delivery.

Rheology Guided Rational Selection of Processing Temperature To Prepare Copovidone-Nifedipine Amorphous Solid Dispersions via Hot Melt Extrusion (HME).

Yongchao Su, James C Dinunzio, Chengbin Huang, 2016, Molecular pharmaceutics.

Industry White Paper: Contemporary Opportunities and Challenges in Characterizing Crystallinity in Amorphous Solid Dispersions.

Stephen L. J. Conway, J. Smoliga, Lili Feng, 2022, Journal of pharmaceutical sciences.

New Peak Detection Performance Metrics from the MAM Consortium Interlaboratory Study.

John E. Schiel, Carly L. Daniels, Thomas W. Powers, 2021, Journal of the American Society for Mass Spectrometry.

Enhanced Precision of Circular Dichroism Spectral Measurements Permits Detection of Subtle Higher Order Structural Changes in Therapeutic Proteins.

Naresh Chennamsetty, R. Ludwig, L. Tao, 2018, Journal of pharmaceutical sciences.

The development of an in vitro assay to screen lipid based nanoparticles for siRNA delivery.

Marian E. Gindy, S. Stirdivant, M. Stanton, 2014, Journal of controlled release : official journal of the Controlled Release Society.

Assessing the heterogeneity level in lipid nanoparticles for siRNA delivery: size-based separation, compositional heterogeneity, and impact on bioperformance.

Y. Pei, Jingtao Zhang, A. Leone, 2013, Molecular pharmaceutics.

Probing the Tryptophan Environment in Therapeutic Proteins: Implications for Higher Order Structure on Tryptophan Oxidation.

Naresh Chennamsetty, Thomas R. Slaney, Laurel Hoffman, 2019, Journal of pharmaceutical sciences.

Development of a liver-targeted siRNA delivery platform with a broad therapeutic window utilizing biodegradable polypeptide-based polymer conjugates.

B. Carr, L. Sepp-Lorenzino, Rob S. Burke, 2014, Journal of controlled release : official journal of the Controlled Release Society.

Unique impacts of methionine oxidation, tryptophan oxidation and asparagine deamidation on antibody stability and aggregation.

Thomas R. Slaney, Lina Wu, T. Das, 2019, Journal of pharmaceutical sciences.

An in vivo evaluation of amphiphilic, biodegradable peptide copolymers as siRNA delivery agents.

B. Carr, K. Leander, L. Sepp-Lorenzino, 2014, International journal of pharmaceutics.

Endosomolytic bioreducible poly(amido amine disulfide) polymer conjugates for the in vivo systemic delivery of siRNA therapeutics.

B. Carr, K. Leander, L. Sepp-Lorenzino, 2013, Bioconjugate chemistry.

Improving the in vivo therapeutic index of siRNA polymer conjugates through increasing pH responsiveness.

L. Sepp-Lorenzino, I. Davies, B. Howell, 2014, Bioconjugate chemistry.

Impact of Tryptophan Oxidation in Complementarity-Determining Regions of Two Monoclonal Antibodies on Structure-Function Characterized by Hydrogen-Deuterium Exchange Mass Spectrometry and Surface Plasmon Resonance

R. Ludwig, L. Tao, T. Das, 2018, Pharmaceutical Research.

Novel endosomolytic poly(amido amine) polymer conjugates for systemic delivery of siRNA to hepatocytes in rodents and nonhuman primates.

B. Carr, K. Leander, L. Sepp-Lorenzino, 2014, Bioconjugate chemistry.

Enabling Efficient Design of Biological Formulations through Advanced Characterizations

Kang Chen, Krishna M. G. Mallela, Jason K. Cheung, 2023, Pharmaceutical Research.