D. Cheng

发表

Regulation and Immunolocalization of Acyl-Coenzyme A:Cholesterol Acyltransferase in Mammalian Cells as Studied with Specific Antibodies (*)

Matthew A. Thomas, M. Pape, Jun Chen, 1995, The Journal of Biological Chemistry.

Induced polymerization of mammalian acetyl-CoA carboxylase by MIG12 provides a tertiary level of regulation of fatty acid synthesis

Sahng-Wook Park, J. Horton, Y. Moon, 2010, Proceedings of the National Academy of Sciences.

Differential activation of recombinant human acetyl-CoA carboxylases 1 and 2 by citrate.

M. Witmer, J. Marcinkeviciene, A. Rendina, 2008, Archives of biochemistry and biophysics.

Human acyl-CoA:diacylglycerol acyltransferase is a tetrameric protein.

P. Young, J. Billheimer, R. Meegalla, 2001, The Biochemical journal.

A novel direct homogeneous assay for ATP citrate lyase[S]

C. Chu, Zhengping Ma, D. Cheng, 2009, Journal of Lipid Research.

Monoacylglycerol Acyltransferase 2 (MGAT2) Inhibitors for the Treatment of Metabolic Diseases and Nonalcoholic Steatohepatitis (NASH).

D. Cheng, P. Devasthale, 2018, Journal of medicinal chemistry.

Concerted elevation of acyl-coenzyme A:diacylglycerol acyltransferase (DGAT) activity through independent stimulation of mRNA expression of DGAT1 and DGAT2 by carbohydrate and insulin.

J. Billheimer, R. Meegalla, D. Cheng, 2002, Biochemical and biophysical research communications.

Expression, purification, and characterization of human and rat acetyl coenzyme A carboxylase (ACC) isozymes.

C. Chu, G. Mintier, J. Feder, 2007, Protein expression and purification.

Acyl coenzyme A dependent retinol esterification by acyl coenzyme A: diacylglycerol acyltransferase 1.

C. Chu, K. Anwar, M. Hussain, 2005, Biochimica et biophysica acta.

MGAT2 inhibitor decreases liver fibrosis and inflammation in murine NASH models and reduces body weight in human adults with obesity.

C. Chu, E. A. Brown, D. Gordon, 2022, Cell metabolism.

Activation of acyl-CoA cholesterol acyltransferase: Redistribution in microsomal fragments of cholesterol and its facilitated movement by methyl-β-cyclodextrin

C. L. Tipton, D. Cheng, 1999, Lipids.

Integrin αVβ1 Regulates Procollagen I Production through a Non-canonical Transforming Growth Factor β Signaling Pathway in Human Hepatic Stellate Cells.

Ruihua Chen, Zhengping Ma, M. Cvijic, 2021, The Biochemical journal.

A simple homogeneous scintillation proximity assay for acyl-coenzyme A:diacylglycerol acyltransferase.

C. Chu, R. Seethala, Rajasree Golla, 2008, Analytical biochemistry.

Tricks for Receptors Applied to an Enzyme: Insights to MGAT2 Inhibitors Using Binding Assays with a Novel Probe

D. Cheng, 2016 .

Acylation of Acylglycerols by Acyl Coenzyme A:Diacylglycerol Acyltransferase 1 (DGAT1)

C. Chu, R. Seethala, R. Lawrence, 2008, Journal of Biological Chemistry.

A homogeneous scintillation proximity assay for acetyl coenzyme A carboxylase coupled to fatty acid synthase.

R. Seethala, Rajasree Golla, Zhengping Ma, 2006, Analytical biochemistry.

A novel calcium-binding peptide from Antarctic krill protein hydrolysates and identification of binding sites of calcium-peptide complex.

Xiao Zhu, Ba-fang Li, Qiqi Li, 2018, Food chemistry.

Identification of Monosaccharide Derivatives as Potent, Selective, and Orally Bioavailable Inhibitors of Human and Mouse Galectin-3.

B. Beno, A. Mathur, Chunjian Liu, 2022, Journal of medicinal chemistry.

Prevalence, predisposition and prevention of type II diabetes

D. Cheng, Dong Cheng, 2005, Nutrition & metabolism.

Screening Hit to Clinical Candidate: Discovery of BMS-963272, a Potent, Selective MGAT2 Inhibitor for the Treatment of Metabolic Disorders.

Kimberly A. Foster, C. Chu, A. Mathur, 2021, Journal of medicinal chemistry.

Acyl-coenzyme A:cholesterol acyltransferase.

T. Chang, D. Cheng, Ta-Yuan Chang, 1997, Annual review of biochemistry.

Synthesis of neutral ether lipid monoalkyl-diacylglycerol by lipid acyltransferases[S]

Zhengping Ma, C. L. Yen, D. Cheng, 2017, Journal of Lipid Research.

Synthesis, Structure-Activity Relationships, and In Vivo Evaluation of Novel Tetrahydropyran-Based Thiodisaccharide Mimics as Galectin-3 Inhibitors.

B. Beno, Amit Kumar, K. Ghosh, 2021, Journal of medicinal chemistry.

Identification of Acyl Coenzyme A:Monoacylglycerol Acyltransferase 3, an Intestinal Specific Enzyme Implicated in Dietary Fat Absorption*

R. Taub, J. Feder, J. Billheimer, 2003, The Journal of Biological Chemistry.

Activation of Acyl-Coenzyme A:Cholesterol Acyltransferase by Cholesterol or by Oxysterol in a Cell-free System (*)

Catherine C. Y. Chang, Ta-Yuan Chang, D. Cheng, 1995, The Journal of Biological Chemistry.

2-hydroxy-N-arylbenzenesulfonamides as ATP-citrate lyase inhibitors.

Dong Cheng, Ramesh Padmanabha, Kristen Pike, 2007, Bioorganic & medicinal chemistry letters.

Expression, purification, characterization of human 3-methylcrotonyl-CoA carboxylase (MCCC).

C. Chu, D. Cheng, 2007, Protein expression and purification.

Characterization of the inactivation of rat fatty acid synthase by C75: inhibition of partial reactions and protection by substrates.

A. Rendina, D. Cheng, 2005, The Biochemical journal.

Molecular identification of the sterol-regulated luminal protease that cleaves SREBPs and controls lipid composition of animal cells.

P. Espenshade, M. Brown, J. Goldstein, 1998, Molecular cell.

Potent biphenyl- and 3-phenyl pyridine-based inhibitors of acetyl-CoA carboxylase.

Christopher B. Cooper, M. Poss, R. Seethala, 2009, Bioorganic & medicinal chemistry letters.

Human Acyl-CoA:Cholesterol Acyltransferase-1 in the Endoplasmic Reticulum Contains Seven Transmembrane Domains*

Jun Chen, Song Lin, Ta-Yuan Chang, 1999, The Journal of Biological Chemistry.

Secreted Site-1 Protease Cleaves Peptides Corresponding to Luminal Loop of Sterol Regulatory Element-binding Proteins*

C. Slaughter, P. Espenshade, J. Goldstein, 1999, The Journal of Biological Chemistry.

A novel solution phase PAI-1/uPA-biotin complex assay for the measurement of active PAI-1 in plasma.

Zhengping Ma, D. Cheng, 2018, Analytical biochemistry.

Liquid-liquid extraction coupled with LC/MS/MS for monitoring of malonyl-CoA in rat brain tissue

Zhengping Ma, P. Shipkova, A. Azzará, 2010, Analytical and bioanalytical chemistry.

Localization of HSV-I ICP22 Protein in Cells by Antibody Against a predicted Antigenic Peptide

D. Cheng, 2006 .

Disconnection between the early onset anorectic effects by C75 and hypothalamic fatty acid synthase inhibition in rodents.

B. Largent, R. Taub, Cecilia L Chi, 2005, European journal of pharmacology.

Discovery of Novel Pyridinones as MGAT2 Inhibitors for the Treatment of Metabolic Disorders.

Kimberly A. Foster, C. Chu, A. Mathur, 2023, Bioorganic & Medicinal Chemistry Letters.

Acylation of Acylglycerols by Acyl Coenzyme A:Diacylglycerol Acyltransferase 1 (DGAT1)

C. Chu, R. Seethala, J. Iqbal, 2008, Journal of Biological Chemistry.

Discovery and exploration of monosaccharide linked dimers of galectin-3 inhibitors to target fibrosis

B. Beno, J. Yanchunas, Chunjian Liu, 2023, Medicinal Chemistry Research.

Study of avian Acyl-CoA Cholesterol Acyltransferase

D. Cheng, 1997 .