Lu Chen

Novel strategies for risk assessment of pyrrolizidine alkaloids

Lu Chen, 2019 .

Use of an in vitro–in silico testing strategy to predict inter-species and inter-ethnic human differences in liver toxicity of the pyrrolizidine alkaloids lasiocarpine and riddelliine

I. Rietjens, J. Louisse, J. Ning, 2019, Archives of Toxicology.

Use of physiologically based kinetic modelling-facilitated reverse dosimetry to convert in vitro cytotoxicity data to predicted in vivo liver toxicity of lasiocarpine and riddelliine in rat.

I. Rietjens, J. Louisse, J. Ning, 2018, Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association.

Risk assessment of intake of pyrrolizidine alkaloids from herbal teas and medicines following realistic exposure scenarios.

I. Rietjens, P. Mulder, A. Peijnenburg, 2019, Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association.

Risk assessment of genotoxic and carcinogenic alkenylbenzenes in botanical containing products present on the Chinese market.

I. Rietjens, J. Ning, S. Wesseling, 2018, Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association.

Role of toxicokinetics and alternative testing strategies in pyrrolizidine alkaloid toxicity and risk assessment; state-of-the-art and future perspectives.

I. Rietjens, J. Ning, Lu Chen, 2019, Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association.

Risk assessment for pyrrolizidine alkaloids detected in (herbal) teas and plant food supplements

I. Rietjens, P. Mulder, A. Peijnenburg, 2017, Regulatory toxicology and pharmacology : RTP.

Risk Assessment of (Herbal) Teas Containing Pyrrolizidine Alkaloids (PAs) Based on Margin of Exposure Approach and Relative Potency (REP) Factors

Lu Chen, Qian Zhang, Dan Su, 2022, Foods.

Prediction of in vivo genotoxicity of lasiocarpine and riddelliine in rat liver using a combined in vitro-physiologically based kinetic modelling-facilitated reverse dosimetry approach

I. Rietjens, A. Peijnenburg, L. D. de Haan, 2019, Archives of Toxicology.

Selecting the dose metric in reverse dosimetry based QIVIVE

I. Rietjens, J. Louisse, J. Ning, 2019, Archives of Toxicology.