A. S. Prakash

发表

The possible role of arsenic in inhibition of DNA repair mechanisms in vivo

M. Moore, J. Ng, H. Tran, 2001 .

A metabolite of the carcinogen 7,12-dimethylbenz[a]anthracene that reacts predominantly with adenine residues in DNA.

A. Dipple, S. Cheng, R. Harvey, 1988, Carcinogenesis.

Mutagenicity and DNA damage studies of N-acyloxy-N-alkoxyamides--the role of electrophilic nitrogen.

A. S. Prakash, S. Glover, A. Bonin, 2003, Organic & biomolecular chemistry.

Characterization of 5-methylchrysene-1,2-dihydrodiol-3,4-epoxide-DNA adducts.

J. M. Roman, D. Reardon, A. Dipple, 1987, Carcinogenesis.

Bracken (Pteridium aquilinum)-induced DNA adducts in mouse tissues are different from the adduct induced by the activated form of the Bracken carcinogen ptaquiloside.

A. Povey, P. O'connor, R. Freitas, 2001, Biochemical and biophysical research communications.

Bracken fern carcinogenesis: multiple intravenous doses of activated ptaquiloside induce DNA adducts, monocytosis, increased TNF alpha levels, and mammary gland carcinoma in rats.

M. Moore, A. Seawright, B. Smith, 1998, Biochemical and biophysical research communications.

Mechanism of action of fotemustine, a new chloroethylnitrosourea anticancer agent: evidence for the formation of two DNA-reactive intermediates contributing to cytotoxicity.

G. Eaglesham, P. Parsons, J. Bartley, 1997, Biochemistry.

Arsenic inhibits the repair of DNA damage induced by benzo(a)pyrene.

B. Chiswell, J. Ng, H. Tran, 2002, Toxicology letters.

DNA‐binding studies of XSPTSPSZ, derivatives of the intercalating heptad repeat of RNA polymerase II

J. Mackay, G. Krippner, A. Rodger, 1997, Biopolymers.

The in vitro cytotoxicity and DNA alkylating ability of the simplest functional analogues of the seco CC-1065 alkylating subunit

P. Parsons, D. Young, R. H. White, 1995 .

Comparison of the sequence selectivity of the DNA-alkylating pluramycin antitumour antibiotics DC92-B and hedamycin.

V. Murray, W. Mcfadyen, A. S. Prakash, 1995, Chemico-biological interactions.

DNA-binding properties and antitumour activity of monofunctional alkylating groups attached to the DNA-intercalating chromophore phenanthridine: n-bromoalkylphenanthridinium bromides.

L. P. Wakelin, W. Mcfadyen, A. S. Prakash, 1991, Biochimica et biophysica acta.

Differences in sequence selectivity of DNA alkylation by isomeric intercalating aniline mustards.

W. Denny, L. P. Wakelin, A. S. Prakash, 1990, Chemico-biological interactions.

Stability and DNA alkylation rates of the simplest functional analogues of CC-1065, para-hydroxy and para-amino phenethyl bromides.

D. Young, C. L. Brown, A. S. Prakash, 1999, Chemico-biological interactions.

Pyrrolizidine alkaloids in human diet.

A S Prakash, A. Seawright, P E Reilly, 1999, Mutation research.

Bracken carcinogens in the human diet.

B. Smith, A. S. Prakash, M. Shahin, 1999, Mutation research.

Dehydromonocrotaline generates sequence-selective N-7 guanine alkylation and heat and alkali stable multiple fragment DNA crosslinks.

A. Seawright, T. Pereira, A. S. Prakash, 1998, Nucleic acids research.

DT-diaphorase in activation and detoxification of quinones

D. Ross, D. Siegel, R. Mulcahy, 1993, Cancer and Metastasis Reviews.

Mechanism of bracken fern carcinogenesis: evidence for H-ras activation via initial adenine alkylation by ptaquiloside.

G. Shaw, A. Seawright, B. Smith, 1998, Natural toxins.

A comparison of the intercalative binding of non-reactive benzo[a]pyrene metabolites and metabolite model compounds to DNA.

R. Harvey, P. Lebreton, M. Abramovich, 1985, Chemico-biological interactions.

DNA-directed alkylating ligands as potential antitumor agents: sequence specificity of alkylation by intercalating aniline mustards.

W. Denny, L. P. Wakelin, A. S. Prakash, 1990, Biochemistry.

Mutagenicity of electrophilic N-acyloxy-N-alkoxyamides.

J. Campbell, A. S. Prakash, S. Glover, 2001, Mutation research.

Kinetics of DNA alkylation, depurination and hydrolysis of anti diol epoxide of benzo(a)pyrene and the effect of cadmium on DNA alkylation.

C. Peng, C. Dameron, A. S. Prakash, 2000, Chemico-biological interactions.

Acridinecarboxamide topoisomerase poisons: structural and kinetic studies of the DNA complexes of 5-substituted 9-amino-(N-(2-dimethylamino)ethyl)acridine-4-carboxamides.

W. Denny, J. Guss, C. Collyer, 2000, Molecular pharmacology.

Characterization of 7,12-dimethylbenz[a]anthracene-adenine nucleoside adducts.

J. M. Roman, A. Dipple, S. Cheng, 1988, Chemical research in toxicology.

Stereoelectronic aspects of the intercalative binding of benz[a]anthracene metabolite models to DNA

M. Shahbaz, P. Lebreton, A. S. Prakash, 2009 .

Intercalative DNA binding of model compounds derived from metabolites of 7,12-dimethylbenz[a]anthracene.

P. Lebreton, A. S. Prakash, I. Zegar, 1984, Journal of biomolecular structure & dynamics.

Fluorescence and photoelectron studies of the intercalative binding of benz(a)anthracene metabolite models to DNA.

R. Harvey, M. Shahbaz, P. Lebreton, 1983, Biochemical and biophysical research communications.

Sequence-selective alkylation and cross-linking induced by mitomycin C upon activation by DT-diaphorase.

N. Gibson, H. Beall, A. S. Prakash, 1993, Biochemistry.

H-ras activation is an early event in the ptaquiloside-induced carcinogenesis: Comparison of acute and chronic toxicity in rats

M. Moore, A. Seawright, S. Worrall, 1998 .

Cadmium inhibits BPDE alkylation of DNA in the major groove but not in the minor groove.

C. Dameron, A. S. Prakash, K. Rao, 1998, Biochemical and biophysical research communications.

H-ras activation is an early event in the ptaquiloside-induced carcinogenesis: comparison of acute and chronic toxicity in rats.

M. Moore, A. Seawright, B. Smith, 1998, Biochemical and biophysical research communications.

Stereoelectronic aspects of the intercalative binding properties of 7,12-dimethylbenz[a]anthracene metabolites with DNA

R. Harvey, P. Lebreton, A. S. Prakash, 1985 .

Synthesis and anti-tumour activity of the spatially-separated mustard bis-N,N'-[3-(N-(2-chloroethyl)-N-ethyl)amino-5-[N,N-dimethylamino)methy l)-aminophenyl]-1,4-benzenedicarboxamide, which alkylates DNA exclusively at adenines in the minor groove.

W. Denny, A. S. Prakash, P. D. Woodgate, 1991, Anti-cancer drug design.

Sequence-selective depurination, DNA interstrand cross-linking and DNA strand break formation associated with alkylated DNA.

N. Gibson, A. S. Prakash, 1992, Carcinogenesis.