T. Toyoda

A. Viari, V. Deubel, P. Buchy, 2013, Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases.

Shedding of the Pandemic Swine-Origin Influenza A Virus (H1N1) after Oseltamivir Administration

Qiang Wang, V. Deubel, Wei Wang, 2010, Influenza research and treatment.

Isolation of Amantadine-Resistant Influenza A Viruses (H3N2) from Patients following Administration of Amantadine in Japan

H. Maeda, N. Hamada, T. Ishibashi, 2001, Journal of Clinical Microbiology.

Influenza A/H5N1 virus infection in humans in Cambodia.

J. Peiris, J. Peiris, N. Tien, 2007, Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology.

Internal Initiation of Influenza Virus Replication of Viral RNA and Complementary RNA in Vitro*

Shijian Zhang, Qiang Wang, T. Toyoda, 2010, The Journal of Biological Chemistry.

Substitution of amino acid residue in influenza A virus hemagglutinin affects recognition of sialyl‐oligosaccharides containing N‐glycolylneuraminic acid

Y. Kawaoka, A. Ishihama, M. Kiso, 1999, FEBS letters.

Defective terminal differentiation and hypoplasia of the epidermis in mice lacking the Fgf10 gene

B. Andersen, S. Kato, Kentarou Suzuki, 2000, FEBS letters.

Ambisense coding strategy of the rice stripe virus genome: in vitro translation studies.

A. Ishihama, T. Toyoda, S. Toriyama, 1993, The Journal of general virology.

Detection of polycistronic transcripts in Newcastle disease virus infected cells and identification of their sequence content

M. Hamaguchi, Y. Nagai, T. Toyoda, 2005, Archives of Virology.

Antibody-scanning and epitope-tagging methods; molecular mapping of proteins using antibodies.

N. Hamada, T. Kashiwagi, J. Iwahashi, 2000, Current protein & peptide science.

Monoclonal antibody recognizing SLLTEVET epitope of M2 protein potently inhibited the replication of influenza A viruses in MDCK cells.

T. Toyoda, Hong-wei Xu, Tianhou Wang, 2009, Biochemical and biophysical research communications.

Protease activity of influenza virus RNA polymerase PA subunit

H. Kido, K. Hara, T. Toyoda, 2001 .

Molecular Evolution of Human Echovirus 9 Isolated from Patients with Aseptic Meningitis in Northern Kyushu during the Summer of 1997

N. Hamada, T. Kashiwagi, J. Iwahashi, 2001, Microbiology and immunology.

Inhibition of the Protease Activity of Influenza Virus RNA Polymerase PA Subunit by Viral Matrix Protein

K. Nagata, Ken-ichi Watanabe, H. Kido, 2003, Microbiology and immunology.

Ser624 of the PA subunit of Influenza A virus is not essential for viral growth in cells and mice, but required for the maximal viral growth

Y. Imamura, K. Hara, T. Toyoda, 2003, Archives of Virology.

Non-nucleoside hepatitis B virus polymerase inhibitors identified by an in vitro polymerase elongation assay

M. Muramatsu, Senko Tsukuda, T. Wakita, 2019, Journal of Gastroenterology.

Paramyxovirus Metabolisms Associated with the Cytoskeletal Framework

M. Hamaguchi, Y. Nagai, T. Toyoda, 1988 .

A simple and rapid method for preliminary evaluation of in vivo efficacy of anti-HIV compounds in mice.

O. Yoshie, H. Sugimoto, K. Abe, 1995, Antiviral research.

The RNA polymerase PB2 subunit is not required for replication of the influenza virus genome but is involved in capped mRNA synthesis

A. Ishihama, K. Mizumoto, K. Oda, 1995, Journal of virology.

Evaluation of the antiviral effect of synthetic oligopeptides whose sequences are derived from paramyxovirus F1 N termini

Y. Nagai, C. Kitada, T. Toyoda, 2004, Medical Microbiology and Immunology.

An endoprotease homologous to the blood clotting factor X as a determinant of viral tropism in chick embryo.

M. Hamaguchi, Y. Nagai, T. Toyoda, 1990, The EMBO journal.

Epitope mapping of the influenza A virus RNA polymerase PA using monoclonal antibodies

Y. Kawaoka, A. Ishihama, T. Ito, 2000, Archives of Virology.

Epitope mapping of the influenza A virus RNA polymerase PA using monoclonal antibodies

Y. Kawaoka, A. Ishihama, T. Ito, 2014, Archives of Virology.

Molecular mapping of influenza virus RNA polymerase by site-specific antibodies.

A. Ishihama, K. Mizumoto, T. Toyoda, 1999, Virology.

Mapping of functional domains on the influenza A virus RNA polymerase PB2 molecule using monoclonal antibodies

Y. Kawaoka, A. Ishihama, T. Ito, 2014, Archives of Virology.

Different mechanisms of hepatitis C virus RNA polymerase activation by cyclophilin A and B in vitro.

M. Kohara, K. Shimotohno, T. Wakita, 2012, Biochimica et biophysica acta.

Antigenic characterization of the internal proteins of Newcastle disease virus by monoclonal antibodies.

T. Yoshida, M. Hamaguchi, Y. Nagai, 1987, Virus research.

Topological and operational delineation of antigenic sites on the HN glycoprotein of Newcastle disease virus and their structural requirements

T. Yokochi, T. Yoshida, Y. Nagai, 1986, Journal of virology.

Growth restriction of negative-strand-RNA viruses in a rat 3Y1 cell line

K. Shimokata, H. Saso, Y. Nagai, 2004, Medical Microbiology and Immunology.

Fluorescence-based biochemical analysis of human hepatitis B virus reverse transcriptase activity.

Y. Wen, Yasuhito Tanaka, Yongxiang Wang, 2020, Analytical biochemistry.

Sphingomyelin Activates Hepatitis C Virus RNA Polymerase in a Genotype-Specific Manner

Y. Hirata, M. Kohara, K. Shimotohno, 2010, Journal of Virology.

Studies on the adaptation of mumps virus to chick embryo

T. Yoshida, M. Hamaguchi, Y. Nagai, 2005, Medical Microbiology and Immunology.

The Polypeptides of Human Parainfluenza 1 (HA‐2) Virus and Their Antigenic Relationships to Those of Sendai Virus (HVJ)

Y. Nakayama, M. Hamaguchi, Y. Nagai, 1985, Microbiology and immunology.

The uncoating of paramyxoviruses may not require a low pH mediated step.

T. Yoshida, M. Hamaguchi, Y. Nagai, 1983, Virology.

Host-specific genetic variation of highly pathogenic avian influenza viruses (H5N1)

K. Ikuta, Yohei Watanabe, H. Ellakany, 2011, Virus Genes.

Structural features unique to each of the three antigenic sites on the hemagglutinin-neuraminidase protein of Newcastle disease virus.

M. Hamaguchi, Y. Nagai, T. Sakaguchi, 1988, Virology.

Biochemical and Structural Properties of Entecavir-Resistant Hepatitis B Virus Polymerase with L180M/M204V Mutations

H. Mitsuya, M. Muramatsu, K. Maeda, 2021, Journal of virology.

Influenza virus RNA polymerase PA subunit is a novel serine protease with Ser624 at the active site

H. Kido, N. Hamada, T. Kashiwagi, 2001, Genes to cells : devoted to molecular & cellular mechanisms.

Nucleotide sequence of the gene encoding the RNA polymerase and the 3′ non-coding region of a bovine enterovirus Japanese isolate: rapid synonymous substitutions between European and Japanese strains

H. Maeda, N. Hamada, T. Toyoda, 1998, Archives of Virology.

Detergent-induced activation of the hepatitis C virus genotype 1b RNA polymerase.

M. Kohara, K. Shimotohno, T. Wakita, 2012, Gene.

Fluorescent primer-based in vitro transcription system of viral RNA-dependent RNA polymerases.

Shijian Zhang, T. Toyoda, Hongbing Jiang, 2013, Analytical biochemistry.

No association of Borna disease virus with psychiatric disorders among patients in Northern Kyushu, Japan

Yoshihiro Imamura, T. Toyoda, K. Tsuji, 2000, Journal of medical virology.

Inhibition of Influenza Virus Replication by Constrained Peptides Targeting Nucleoprotein

Shijian Zhang, Y. Jacob, Hongxing Hu, 2011, Antiviral chemistry & chemotherapy.

Promoter/Origin Structure of the Complementary Strand of Hepatitis C Virus Genome*

M. Kohara, N. Hamada, T. Kashiwagi, 2002, The Journal of Biological Chemistry.

Biochemical characterization of enterovirus 71 3D RNA polymerase.

M. Arita, Na Zhang, T. Toyoda, 2011, Biochimica et biophysica acta.

Influenza virus genome C4 promoter/origin attenuates its transcription and replication activity by the low polymerase recognition activity.

Shijian Zhang, T. Toyoda, Hongbing Jiang, 2010, Virology.

Hepatitis C Virus NS5B Protein Delays S Phase Progression in Human Hepatocyte-derived Cells by Relocalizing Cyclin-dependent Kinase 2-interacting Protein (CINP)*

Yuchan Wang, Zhenghong Yuan, Yaohui Wang, 2011, The Journal of Biological Chemistry.

Two mutations in the C-terminal domain of influenza virus RNA polymerase PB2 enhance transcription by enhancing cap-1 RNA binding activity.

Shijian Zhang, K. Mizumoto, T. Toyoda, 2012, Biochimica et biophysica acta.

PA from an H5N1 highly pathogenic avian influenza virus activates viral transcription and replication and induces apoptosis and interferon expression at an early stage of infection

Shijian Zhang, M. Kohara, V. Deubel, 2012, Virology Journal.

Molecular mechanisms of transcription and replication of the influenza A virus genome

Shijian Zhang, T. Toyoda, 2011, Frontiers in Biology.

Biochemical and kinetic analysis of the influenza virus RNA polymerase purified from insect cells.

Shijian Zhang, V. Deubel, P. Buchy, 2010, Biochemical and biophysical research communications.

Regulatory effects of matrix protein variations on influenza virus growth

A. Ishihama, J. Yasuda, T. Toyoda, 2005, Archives of Virology.

Lead discovery of inhibitors of the dihydrofolate reductase domain of Plasmodium falciparum dihydrofolate reductase-thymidylate synthase.

N. Tomioka, A. Itai, T. Horii, 1997, Biochemical and biophysical research communications.

Caenorhabditis elegans reticulon interacts with RME-1 during embryogenesis.

Y. Kohara, K. Gengyo-Ando, S. Mitani, 2002, Biochemical and biophysical research communications.

Replication in vitro of the influenza virus genome: selective dissociation of RNA replicase from virus-infected cell ribonucleoprotein complexes

A. Ishihama, T. Toyoda, M. Kobayashi, 2005, Archives of Virology.

Molecular dissection of influenza virus RNA polymerase: PB1 subunit alone is able to catalyze RNA synthesis

A. Ishihama, T. Toyoda, Makoto Kobayashi, 2004, Virus Genes.

Fine Mapping of the Subunit Binding Sites of Influenza Virus RNA Polymerase

Y. Honda, T. Toyoda, Y. Ohtsu, 2002 .

Fine mapping of the subunit binding sites of influenza virus RNA polymerase.

Y. Honda, T. Toyoda, Y. Ohtsu, 2001, Microbiology and immunology.

Role of γδ TCR M lymphocytes in the augmented resistance of trehalose 6 , 6 «-dimycolate-treated mice to influenza virus infection

T. Suzutani, M. Azuma, I. Yoshida, 1997 .

Reticulon3 expression in rat optic and olfactory systems

Takahiro Fujimoto, Eiichi Taira, L. Zeng, 2004, Neuroscience Letters.

Role of gamma delta TCR+ lymphocytes in the augmented resistance of trehalose 6,6'-dimycolate-treated mice to influenza virus infection.

T. Suzutani, M. Azuma, I. Yoshida, 1997, The Journal of general virology.

The N-terminal helix α(0) of hepatitis C virus NS3 protein dictates the subcellular localization and stability of NS3/NS4A complex.

Jin Zhong, T. Toyoda, Leiyun Weng, 2012, Virology.

[Emergence of amantadine-resistant influenza A viruses].

T. Ishibashi, Y. Imamura, J. Iwahashi, 2001, Uirusu.

Newcastle disease virus evolution. I. Multiple lineages defined by sequence variability of the hemagglutinin-neuraminidase gene.

K. Kuma, T. Miyata, Y. Nagai, 1989, Virology.

Inhibition of influenza virus replication in cultured cells by RNA‐cleaving DNA enzyme

H. Takaku, N. Hamada, Y. Imamura, 2000, FEBS letters.

Molecular dissection of influenza virus nucleoprotein: deletion mapping of the RNA binding domain

A. Ishihama, D. Adyshev, T. Toyoda, 1994, Journal of virology.

Metabolism of tulip bulbs as related to thermoperiodicity

H. Ito, T. Kato, T. Toyoda, 1960 .

RNA Polymerase Activity and Specific RNA Structure Are Required for Efficient HCV Replication in Cultured Cells

M. Mizokami, Yasuhito Tanaka, T. Wakita, 2010, PLoS pathogens.

Influenza virus PB1 protein is the minimal and essential subunit of RNA polymerase

A. Ishihama, T. Toyoda, M. Kobayashi, 2005, Archives of Virology.

Characterization of the influenza virus knocked out of PA protease activity

T. Toyoda, 2004 .

Detection of viral antigens in the encephalopathy brain by influenza A virus

Tatsuo Yamada, Mitsuo Takahashi, T. Toyoda, 2001 .

Newcastle disease virus evolution. II. Lack of gene recombination in generating virulent and avirulent strains.

K. Kuma, T. Miyata, H. Hirota, 1989, Virology.

Identification of amino acids relevant to three antigenic determinants on the fusion protein of Newcastle disease virus that are involved in fusion inhibition and neutralization

Y. Nagai, H. Kida, T. Sakaguchi, 1988, Journal of virology.

Role of GTPase activity of murine Mx1 protein in nuclear localization and anti-influenza virus activity.

A. Ishihama, T. Toyoda, Y. Asano, 1995, Journal of General Virology.

Molecular cloning and characterization of the mouse reticulon 3 cDNA.

N. Hamada, Kentarou Suzuki, T. Yamada, 2002, Cellular and Molecular Biology.

DNA microarray analysis of encephalitis/encephalopathy by influenza virus

T. Matsuishi, S. Miyazaki, M. Matsuo, 2004 .

[Molecular dissection of the influenza virus RNA polymerase].

T. Toyoda, 1996, Uirusu.

Molecular assembly of influenza virus: association of the NS2 protein with virion matrix.

A. Ishihama, A. Kato, A. Kato, 1993, Virology.

Studies of bovine enterovirus structure by ultraviolet resonance Raman spectroscopy.

T. Kitagawa, T. Toyoda, S. Kaminaka, 1999, Journal of virological methods.

Chronic myelogenous leukemia with a complex Ph1 translocation in an XYY male.

M. Oshimura, K. Ohyashiki, K. Yamamoto, 1984, Cancer genetics and cytogenetics.

Monoclonal antibody recognizing SLLTEVET epitope of M2 protein potently inhibited the replication of influenza A viruses in MDCK cells.

T. Toyoda, Hong-wei Xu, Tianhou Wang, 2009, Biochemical and biophysical research communications.

Mechanism of Methotrexate‐sensitivity of Choriocarcinoma Cells in Culture

Y. Nagai, Y. Tomoda, T. Ishizuka, 1988, Japanese journal of cancer research : Gann.

Effect of the methyltransferase domain of Japanese encephalitis virus NS5 on the polymerase activity.

V. Deubel, H. Okada, Xiao Tian, 2012, Biochimica et biophysica acta.