S. Shepherd

发表

Trypanosoma cruzi Phosphomannomutase and Guanosine Diphosphate-Mannose Pyrophosphorylase Ligandability Assessment

M. Ferguson, D. Gray, L. S. Torrie, 2019, Antimicrobial Agents and Chemotherapy.

Pseudomonas aeruginosa 4-Amino-4-Deoxychorismate Lyase: Spatial Conservation of an Active Site Tyrosine and Classification of Two Types of Enzyme

W. Hunter, P. Fyfe, S. Shepherd, 2011, PloS one.

Lysyl-tRNA synthetase, a target for urgently needed M. tuberculosis drugs

Robert H Bates, L. Stojanovski, K. Read, 2022, Nature Communications.

Toolkit of Approaches To Support Target-Focused Drug Discovery for Plasmodium falciparum Lysyl tRNA Synthetase

I. Gilbert, D. Robinson, L. S. Torrie, 2022, ACS infectious diseases.

Lysyl-tRNA synthetase as a drug target in malaria and cryptosporidiosis

Juan A. Bueren-Calabuig, Andrei V. Pisliakov, David W. Gray, 2019, Proceedings of the National Academy of Sciences.

Structure of Pseudomonas aeruginosa inosine 5′-monophosphate dehydrogenase

W. Hunter, S. Shepherd, V. Rao, 2013, Acta crystallographica. Section F, Structural biology and crystallization communications.

Structural insights into mechanism and specificity of O-GlcNAc transferase

A. W. Schüttelkopf, D. V. van Aalten, V. Borodkin, 2008, The EMBO journal.

Structural insights into mechanism and specificity of O-GlcNAc transferase This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits distribution,andreproductioninanymedium,providedtheoriginalauthorandsourcearecredited.Thislicensedoesnot pe

V. Borodkin, S. Shepherd, Shalini Pathak, 2008 .

Crystal Structures of Penicillin-Binding Protein 3 from Pseudomonas aeruginosa: Comparison of Native and Antibiotic-Bound Forms

David I. Stuart, Raymond J. Owens, William N. Hunter, 2011, Journal of molecular biology.

The structure of Serratia marcescens Lip, a membrane-bound component of the type VI secretion system

W. Hunter, S. Coulthurst, Grant English, 2011, Acta crystallographica. Section D, Biological crystallography.

GlcNAcstatin: a picomolar, selective O-GlcNAcase inhibitor that modulates intracellular O-glcNAcylation levels.

D. V. van Aalten, N. Shpiro, V. Borodkin, 2006, Journal of the American Chemical Society.

Structural and kinetic differences between human and Aspergillus fumigatus D-glucosamine-6-phosphate N-acetyltransferase.

J. Min, D. V. van Aalten, A. Plotnikov, 2008, The Biochemical journal.

Glucose‐6‐phosphate as a probe for the glucosamine‐6‐phosphate N‐acetyltransferase Michaelis complex

D. V. van Aalten, O. Raimi, S. Shepherd, 2007, FEBS letters.

Chemogenomics identifies acetyl-coenzyme A synthetase as a target for malaria treatment and prevention

E. Winzeler, I. Gilbert, M. Llinás, 2021, Cell chemical biology.

Molecular mechanism of elongation factor 1A inhibition by a Legionella pneumophila glycosyltransferase.

A. Prescott, D. V. van Aalten, T. Zusman, 2010, The Biochemical journal.

Identification of Leishmania major UDP-Sugar Pyrophosphorylase Inhibitors Using Biosensor-Based Small Molecule Fragment Library Screening

David W. Gray, D. Gray, R. Fedorov, 2019, Molecules.

Identification of Novel Trypanosoma cruzi Proteasome Inhibitors Using a Luminescence-Based High-Throughput Screening Assay

David W. Gray, D. Gray, L. S. Torrie, 2019, Antimicrobial Agents and Chemotherapy.

Molecular Mechanisms of Yeast Cell Wall Glucan Remodeling*

J. Latgé, A. W. Schüttelkopf, D. V. van Aalten, 2009, Journal of Biological Chemistry.

Discovery of an Allosteric Binding Site in Kinetoplastid Methionyl-tRNA Synthetase

David W. Gray, I. Gilbert, A. Fairlamb, 2020, ACS infectious diseases.