B. Munch‐Petersen

发表

Tomato Thymidine Kinase Is Subject to Inefficient TTP Feedback Regulation

J. Piškur, N. B. Larsen, B. Munch‐Petersen, 2014, Nucleosides, nucleotides & nucleic acids.

Structure of the Bacillus subtilis D-aminopeptidase DppA reveals a novel self-compartmentalizing protease

Wolfgang Knecht, Han Remaut, James Leiper, 2001, Nature Structural Biology.

Flow cytometric discrimination of mitotic cells: resolution of M, as well as G1, S, and G2 phase nuclei with mithramycin, propidium iodide, and ethidium bromide after fixation with formaldehyde.

J. Larsen, B. Munch‐Petersen, J. Christiansen, 1986, Cytometry.

Structural basis for feedback inhibition of the deoxyribonucleoside salvage pathway: studies of the Drosophila deoxyribonucleoside kinase.

H. Eklund, J. Piškur, K. Johansson, 2003, Biochemistry.

Flow cytometric discrimination of mitotic cells

I. Christensen, J. Larsen, B. Munch‐Petersen, 1983 .

Induction of thymidine kinases in phytohaemagglutinin-stimulated human lymphocytes.

B. Munch‐Petersen, G. Tyrsted, 1977, Biochimica et biophysica acta.

Two thymidine kinases and one multisubstrate deoxyribonucleoside kinase salvage DNA precursors in Arabidopsis thaliana

J. Piškur, L. Girandon, E. Andreasson, 2012, The FEBS journal.

A few amino acid substitutions can convert deoxyribonucleoside kinase specificity from pyrimidines to purines

H. Eklund, J. Piškur, K. Johansson, 2002, The EMBO journal.

Identification of residues involved in the specificity and regulation of the highly efficient multisubstrate deoxyribonucleoside kinase from Drosophila melanogaster.

J. Piškur, W. Knecht, B. Munch‐Petersen, 2000, Journal of molecular biology.

Gene technology-based antimetabolite design: the use of an in vitro protein expression system to facilitate antimetabolite design for virally-induced human diseases and malignant conditions.

G. Folkers, A. Milon, Y. Barnett, 1994, Biotechnology advances.

Collateral sensitivity to gemcitabine (2',2'-difluorodeoxycytidine) and cytosine arabinoside of daunorubicin- and VM-26-resistant variants of human small cell lung cancer cell lines.

G. Peters, M. Sehested, A. Bergman, 2001, Biochemical pharmacology.

Thymidine kinase isoenzymes in human acute monocytic leukemia

B. Munch‐Petersen, G. Tyrsted, 1985, Molecular and Cellular Biochemistry.

Different affinity of the two forms of human cytosolic thymidine kinase towards pyrimidine analogs.

B. Munch‐Petersen, K. Eger, G. Tyrsted, 1995, Biochimica et biophysica acta.

Human thymidine kinase 1. Regulation in normal and malignant cells.

B. Munch‐Petersen, G. Tyrsted, L. Cloos, 1995, Advances in enzyme regulation.

Thymidine kinase in human leukemia--expression of three isoenzyme variants in six patients with chronic myelocytic leukemia.

B. Munch‐Petersen, 1990, Leukemia research.

Thymidine kinase in human leukemia. Expression of the lymphoblastic isoenzyme in three patients with acute myelocytic leukemia.

B. Munch‐Petersen, G. Tyrsted, 1988, Leukemia research.

Thymidine kinase isoenzymes in human acute and chronic lymphatic leukemia.

B. Munch‐Petersen, G. Tyrsted, 1986, Leukemia research.

Four Deoxynucleoside Kinase Activities from Drosophila melanogaster Are Contained within a Single Monomeric Enzyme, a New Multifunctional Deoxynucleoside Kinase*

J. Piškur, L. Søndergaard, B. Munch‐Petersen, 1998, The Journal of Biological Chemistry.

Deoxynucleoside Kinases and Their Potential Role in Deoxynucleoside Cytotoxicity

J. Piškur, B. Munch‐Petersen, 2006 .

Azidothymidine inhibits mitogen stimulated growth and DNA-repair in human peripheral lymphocytes.

B. Munch‐Petersen, 1988, Biochemical and biophysical research communications.

Immobilized Drosophila melanogaster Deoxyribonucleoside Kinase (DmdNK) as a High Performing Biocatalyst for the Synthesis of Purine Arabinonucleotides

J. Piškur, A. Clausen, M. Terreni, 2014 .

Purification and Characterization of Wild-Type and Mutant Tk1 Type Kinases From Caenorhabditis Elegans

T. Skovgaard, B. Munch‐Petersen, 2006, Nucleosides, nucleotides & nucleic acids.

Mosquito has a single multisubstrate deoxyribonucleoside kinase characterized by unique substrate specificity.

G. Petersen, J. Piškur, L. Søndergaard, 2003, Nucleic acids research.

Non-Viral Deoxyribonucleoside Kinases--Diversity and Practical Use.

W. Knecht, B. Munch‐Petersen, Louise Slot Christiansen, 2015, Journal of genetics and genomics = Yi chuan xue bao.

Thymidine kinase 1 regulatory fine‐tuning through tetramer formation

J. Piškur, A. Clausen, K. Andersson, 2013, The FEBS journal.

Gene duplications and losses among vertebrate deoxyribonucleoside kinases of the non-TK1 Family

J. Piškur, A. Clausen, M. Berchtold, 2016, Nucleosides, nucleotides & nucleic acids.

Abnormal lymphocyte response to u.v. radiation in multiple skin cancer.

M. Faber, K. Wallevik, G. Frentz, 1985, Carcinogenesis.

Increased number of circulating suppressor T‐Lymphocytes in Sun‐induced multiple skin cancers

G. Frentz, B. Munch‐Petersen, G. L. Wantzin, 1988, Cancer.

Striking Ability of Adenosine-2′(3′)-deoxy-3′(2′)-triphosphates and Related Analogues to Replace ATP as Phosphate Donor for All Four Human, and the Drosophila Melanogaster, Deoxyribonucleoside Kinases

S. Eriksson, B. Kierdaszuk, D. Shugar, 2003, Nucleosides, nucleotides & nucleic acids.

Ligands for the affinity chromatography of mammalian thymidine kinase. 1: Strategy, synthesis and evaluation.

B. Munch‐Petersen, K. Eger, G. Tyrsted, 1996, Pharmaceutica acta Helvetiae.

Early effects of phytohemagglutinin on induction of DNA polymerase, thymidine kinase, deoxyribonucleoside triphosphate pools and DNA synthesis in human lymphocytes.

B. Munch‐Petersen, G. Tyrsted, 1977, Nucleic acids research.

The deoxyribonucleoside 5'-triphosphate (dATP and dTTP) pool in phytohemagglutinin-stimulated and non-stimulated human lymphocytes.

B. Munch‐Petersen, G. Tyrsted, B. Dupont, 1973, Experimental cell research.

DNA polymerase activity in phytohemagglutinin-stimulated and non-stimulated human lymphocytes.

B. Munch‐Petersen, G. Tyrsted, L. Cloos, 1973, Experimental cell research.

Effect of deoxynucleosides on the repair of UV induced DNA breaks.

B. Munch‐Petersen, 1998, Advances in experimental medicine and biology.

Thymidine in the micromolar range promotes rejoining of UVC-induced DNA strand breaks and prevents azidothymidine from inhibiting the rejoining in quiescent human lymphocytes.

B. Munch‐Petersen, 1997, Mutation research.

ACTINOMYOES (NOOARDIA) SP. FBOM A BOVINE UDDEB INFECTION

B. Munch‐Petersen, 1954 .

Plant thymidine kinase 1: a novel efficient suicide gene for malignant glioma therapy.

T. Ekström, J. Piškur, P. Kristoffersen, 2010, Neuro-oncology.

The nevoid basal cell carcinoma syndrome: sensitivity to ultraviolet and x-ray irradiation.

E. Niebuhr, G. Frentz, B. Munch‐Petersen, 1987, Journal of the American Academy of Dermatology.

X-ray and UV-radiation sensitivity of circulating lymphocytes in multiple epidermal cancer in relation to previous radiation exposure.

G. Frentz, B. Munch‐Petersen, 1985, Radiation research.

Differences in the kinetic properties of thymidine kinase isoenzymes in unstimulated and phytohemagglutinin-stimulated human lymphocytes

B. Munch‐Petersen, 1984, Molecular and Cellular Biochemistry.

Seasonal variations in UVR-induced DNA synthesis and in UVR inhibition of phytohaemagglutinin-stimulated proliferation of human lymphocytes.

M. Faber, K. Wallevik, B. Munch‐Petersen, 1985, Scandinavian journal of clinical and laboratory investigation.

An Unusual Case of Multiple Malignancy in an Adult

B. Pedersen, H. Wulf, K. Bendtzen, 1984, Tumori.

Diverging substrate specificity of pure human thymidine kinases 1 and 2 against antiviral dideoxynucleosides.

S. Eriksson, B. Munch‐Petersen, G. Tyrsted, 1991, The Journal of biological chemistry.

Comparison of the substrate specificities of human thymidine kinase 1 and 2 and deoxycytidine kinase toward antiviral and cytostatic nucleoside analogs.

B. Oberg, S. Eriksson, B. Öberg, 1991, Biochemical and biophysical research communications.

Structure and function of cellular deoxyribonucleoside kinases

K. Johansson, S. Eriksson, S. Eriksson, 2002, Cellular and Molecular Life Sciences CMLS.

New Variants of Tomato Thymidine Kinase 1 Selected for Increased Sensitivity of E. coli KY895 towards Azidothymidine

J. Piškur, W. Knecht, B. Munch‐Petersen, 2015, Cancers.

Human thymidine kinase 2: molecular cloning and characterisation of the enzyme activity with antiviral and cytostatic nucleoside substrates

U. Hellman, H. Jörnvall, T. Bergman, 1999, FEBS letters.

Substrate/inhibitor properties of human deoxycytidine kinase (dCK) and thymidine kinases (TK1 and TK2) towards the sugar moiety of nucleosides, including O'-alkyl analogues.

S. Eriksson, U. Jacobsson, B. Kierdaszuk, 1999, Nucleosides & nucleotides.

Structural basis for substrate specificities of cellular deoxyribonucleoside kinases

H. Eklund, J. Piškur, K. Johansson, 2001, Nature Structural Biology.

Mammalian thymidine kinase 2. Direct photoaffinity labeling with [32P]dTTP of the enzyme from spleen, liver, heart and brain.

S. Eriksson, B. Munch‐Petersen, C. Bohman, 1992, European journal of biochemistry.

Substrate/inhibitor specificities of human deoxycytidine kinase (dCK) and thymidine kinases (TK1 and TK2).

S. Eriksson, U. Jacobsson, B. Kierdaszuk, 1997, Advances in experimental medicine and biology.

Structures of thymidine kinase 1 of human and mycoplasmic origin

H. Eklund, S. Eriksson, M. Welin, 2004, Proceedings of the National Academy of Sciences of the United States of America.

Nucleoside triphosphate donors for nucleoside kinases: donor properties of UTP with human deoxycytidine kinase.

B. Kierdaszuk, D. Shugar, S. Eriksson, 1995, Biochemical and biophysical research communications.

Reversible ATP-dependent transition between two forms of human cytosolic thymidine kinase with different enzymatic properties.

B. Munch‐Petersen, G. Tyrsted, L. Cloos, 1993, The Journal of biological chemistry.

Deoxyribonucleoside kinases belonging to the thymidine kinase 2 (TK2)-like group vary significantly in substrate specificity, kinetics and feed-back regulation.

G. Petersen, J. Piškur, W. Knecht, 2002, Journal of molecular biology.

NUCLEOSIDES, NUCLEOTIDES AND NUCLEIC ACIDS

S. Kjærulff, L. Søndergaard, B. Munch‐Petersen, 2016 .

Nucleoside analogues are activated by bacterial deoxyribonucleoside kinases in a species-specific manner.

F. Aarestrup, J. Piškur, A. Clausen, 2007, The Journal of antimicrobial chemotherapy.

Drosophila deoxyribonucleoside kinase mutants with enhanced ability to phosphorylate purine analogs

J. Piškur, L. Hasholt, W. Knecht, 2007, Gene Therapy.

Structural basis for the changed substrate specificity of Drosophila melanogaster deoxyribonucleoside kinase mutant N64D

H. Eklund, J. Piškur, T. Skovgaard, 2005, The FEBS journal.

Effect of valine 106 on structure-function relation of cytosolic human thymidine kinase. Kinetic properties and oligomerization pattern of nine substitution mutants of V106.

H. Frederiksen, B. Munch‐Petersen, D. Berenstein, 2004, European journal of biochemistry.

Functional Expression of a Multisubstrate Deoxyribonucleoside Kinase from Drosophila melanogaster and Its C-terminal Deletion Mutants*

J. Piškur, L. Søndergaard, W. Knecht, 2000, The Journal of Biological Chemistry.

The Role of Mitochondrial dNTP Levels in Cells with Reduced TK2 Activity

L. Rasmussen, B. Munch‐Petersen, C. Desler, 2006, Nucleosides, nucleotides & nucleic acids.

Isolation of a novel protein, P12—from adult Drosophila melanogaster that inhibits deoxyribonucleoside and protein kinase activities and activates 3′-5′- exonuclease activity

S. Kjærulff, L. Søndergaard, B. Munch‐Petersen, 2016, Nucleosides, nucleotides & nucleic acids.

A MATHEMATICAL MODEL OF HUMAN THYMIDINE KINASE 2 ACTIVITY

S. Eriksson, T. Radivoyevitch, B. Munch‐Petersen, 2011, Nucleosides, nucleotides & nucleic acids.

Enzymatic Regulation of Cytosolic Thymidine Kinase 1 and Mitochondrial Thymidine Kinase 2: A Mini Review

B Munch-Petersen, B. Munch‐Petersen, 2010, Nucleosides, nucleotides & nucleic acids.

Deoxycytidylate deaminase activity in non-stimulated and phytohemagglutinin-stimulated human lymphocytes, and in leukemic cells

B. Munch‐Petersen, G. Tyrsted, P. Chao, 1987, Molecular and Cellular Biochemistry.

Altered substrate and inhibitor specificity of purified human adult thymidine kinases (TK2) from leukemic cells.

B. Munch‐Petersen, R. Hofbauer, G. Tyrsted, 1994, Advances in experimental medicine and biology.

Comparative active‐site mutation study of human and Caenorhabditis elegans thymidine kinase 1

U. Uhlin, T. Skovgaard, B. Munch‐Petersen, 2012, The FEBS journal.

Immobilization of Deoxyadenosine Kinase from Dictyostelium discoideum (DddAK) and Its Application in the 5’-Phosphorylation of Arabinosyladenine and Arabinosyl-2-fluoroadenine

J. Piškur, M. Terreni, I. Serra, 2017 .

Functional studies of active‐site mutants from Drosophila melanogaster deoxyribonucleoside kinase

H. Eklund, B. Munch‐Petersen, Louise Egeblad-Welin, 2007, The FEBS journal.

Reversible tetramerization of human TK1 to the high catalytic efficient form is induced by pyrophosphate, in addition to tripolyphosphates, or high enzyme concentration

B. Munch‐Petersen, 2009, The FEBS journal.

Ability of Adenosine-2′(3′)-deoxy-3′(2′)-triphosphates and Related Analogues to Replace ATP as Phosphate Donor for all Human and Drosphila melanogaster Deoxyribonucleoside Kinases

S. Eriksson, B. Kierdaszuk, D. Shugar, 2003, Nucleosides, nucleotides & nucleic acids.

Overexpression of human thymidine kinase mRNA without corresponding enzymatic activity in patients with chronic lymphatic leukemia.

B. Munch‐Petersen, T. Kristensen, H. K. Jensen, 1994, Leukemia research.

Mitochondria as determinant of nucleotide pools and chromosomal stability.

L. Rasmussen, Keshav K. Singh, M. Kulawiec, 2007, Mutation research.

Effect of C-Terminal of Human Cytosolic Thymidine Kinase (TK1) on in Vitro Stability and Enzymatic Properties

C. Zhu, B. Munch‐Petersen, S. Munch-Petersen, 2006, Nucleosides, nucleotides & nucleic acids.

Valine, Not Methionine, Is Amino Acid 106 in Human Cytosolic Thymidine Kinase (TK1)

B. Munch‐Petersen, R. Hofbauer, T. Kristensen, 2000, The Journal of Biological Chemistry.

The single deoxynucleoside kinase in Drosophila melanogaster, Dm-dNK, is multifunctional and differs from the mammalian deoxynucleoside kinases.

J. Piškur, L. Søndergaard, B. Munch‐Petersen, 1998, Advances in experimental medicine and biology.

Altered kinetic properties of recombinant human cytosolic thymidine kinase (TK1) as compared with the native form.

B. Munch‐Petersen, H. K. Jensen, 1994, Advances in experimental medicine and biology.

Expression and substrate specificities of human thymidine kinase 1, thymidine kinase 2 and deoxycytidine kinase.

B. Kierdaszuk, S. Eriksson, B. Munch‐Petersen, 1991, Advances in experimental medicine and biology.

Animal deoxyribonucleoside kinases: ‘forward’ and ‘retrograde’ evolution of their substrate specificity 1

J. Piškur, W. Knecht, B. Munch‐Petersen, 2004, FEBS letters.

Deoxyribonucleoside kinases in two aquatic bacteria with high specificity for thymidine and deoxyadenosine.

D. Liberles, J. Piškur, V. Turk, 2012, FEMS microbiology letters.

Thymidine Kinase Diversity in Bacteria

J. Piškur, A. Clausen, B. Munch‐Petersen, 2006, Nucleosides, nucleotides & nucleic acids.

Recombinant deoxyribonucleoside kinase from Drosophila melanogaster can improve gemcitabine based combined gene/chemotherapy for targeting cancer cells.

Zeeshan Mutahir, Anjum Riaz, B. Munch‐Petersen, 2019, Bosnian journal of basic medical sciences.

Plants Salvage Deoxyribonucleosides in Mitochondria

J. Piškur, A. Clausen, Zeeshan Mutahir, 2014, Nucleosides, nucleotides & nucleic acids.

Structural studies of nucleoside analog and feedback inhibitor binding to Drosophila melanogaster multisubstrate deoxyribonucleoside kinase

H. Eklund, B. Munch‐Petersen, N. Mikkelsen, 2008, The FEBS journal.

Quantitation of TK1 mRNA in patients with chronic lymphatic leukemia.

B. Munch‐Petersen, T. Kristensen, H. K. Jensen, 1994, Advances in experimental medicine and biology.

Polyclonal antibodies against the ultrafast multisubstrate deoxyribonucleoside kinase from Drosophila melanogaster.

J. Piškur, W. Knecht, B. Munch‐Petersen, 2000, Advances in experimental medicine and biology.

Increased ratio between deoxycytidine kinase and thymidine kinase 2 in CLL lymphocytes compared to normal lymphocytes.

B. Munch‐Petersen, J. Mejer, S. E. Nielsen, 1995, Leukemia research.

Normal sister chromatid exchange in lymphocytes from patients with multiple epidermal cancer?

E. Niebuhr, G. Frentz, B. Munch‐Petersen, 2004, Archives of Dermatological Research.

A multisubstrate deoxyribonucleoside kinase from plants.

J. Piškur, L. Girandon, E. Andreasson, 2008, Nucleic Acids Symposium Series.

UV-induced alterations in skin and lymphocytes during a one-week holiday in the Canary Islands in May.

H. Wulf, T. Poulsen, B. Munch‐Petersen, 1993, Acta dermato-venereologica.

Elevated ratio between deoxycytidine kinase and thymidine kinase 2 in CLL lymphocytes compared to control cells.

B. Munch‐Petersen, J. Mejer, S. E. Nielsen, 1994, Advances in experimental medicine and biology.

Non-Viral Deoxyribonucleoside Kinases--Diversity and Practical Use.

W. Knecht, B. Munch‐Petersen, Louise Slot Christiansen, 2015, Journal of genetics and genomics = Yi chuan xue bao.