S. Hanlon

发表

Amine Transaminase Engineering for Spatially Bulky Substrate Acceptance

U. Bornscheuer, H. Iding, I. V. Pavlidis, 2017, Chembiochem : a European journal of chemical biology.

Development of a Scalable Synthesis of (S)-3-Fluoromethyl-γ-butyrolactone, Building Block for Carmegliptin’s Lactam Moiety

B. Wirz, S. Hanlon, Jean-Michel Adam, 2011 .

Screening methods for enzyme-mediated alcohol oxidation

M. Contente, F. Paradisi, D. Wetzl, 2022, Scientific Reports.

Dimethylsulfide:acceptor oxidoreductase from Rhodobacter sulfidophilus. The purified enzyme contains b-type haem and a pterin molybdenum cofactor.

A. McEwan, R. Holt, P. Solomon, 1996, European journal of biochemistry.

Dimethylsulfide as an electron donor in Rhodobacter sulfidophilus

A. McEwan, P. Solomon, A. Shaw, 1996 .

Biocatalysis in the Fine Chemical and Pharmaceutical Industries

Joseph P. Adams, Peter W. Sutton, Roger M. Howard, 2012 .

Metabolite Identification via LC‐SPE‐NMR‐MS of the In vitro Biooxidation Products of a Lead mGlu5 Allosteric Antagonist and Impact on the Improvement of Metabolic Stability in the Series

W. Spooren, J. Peters, S. Ceccarelli, 2008, ChemMedChem.

Isolation and characterization of a strain of Rhodobacter sulfidophilus: A bacterium which grows autotrophically with dimethylsulphide as electron donor

A. McEwan, G. Moore, R. Holt, 1994 .

Protein-engineering of an amine transaminase for the stereoselective synthesis of a pharmaceutically relevant bicyclic amine.

U. Bornscheuer, H. Iding, I. V. Pavlidis, 2016, Organic & biomolecular chemistry.

The Organic–Synthetic Potential of Recombinant Ene Reductases: Substrate‐Scope Evaluation and Process Optimization

H. Gröger, W. Hummel, H. Iding, 2015 .

Expression of recombinant human flavin monooxygenase and moclobemide-N-oxide synthesis on multi-mg scale.

Anton Glieder, Sandra Abad, Beat Wirz, 2012, Chemical communications.

Expanding the Imine Reductase Toolbox by Exploring the Bacterial Protein‐Sequence Space

Michael Müller, M. Ebeling, D. Wetzl, 2015, Chembiochem : a European journal of chemical biology.

Human Enzymes for Organic Synthesis

Bernd Nidetzky, Martina Geier, Anton Glieder, 2018, Angewandte Chemie.

The use of enzymes in organic synthesis and the life sciences: perspectives from the Swiss Industrial Biocatalysis Consortium (SIBC)

Roland Wohlgemuth, Steven P. Hanlon, S. Lütz, 2013 .

Asymmetric reduction of racemic sulfoxides by dimethyl sulfoxide reductases from Rhodobacter capsulatus, Escherichia coli and Proteus species.

D. L. Graham, A. McEwan, R. Holt, 1998, Microbiology.

Asymmetric Reductive Amination of Ketones Catalyzed by Imine Reductases

Alfred Ross, Hans Iding, Dennis Wetzl, 2016 .

Identification of (S)-selective transaminases for the asymmetric synthesis of bulky chiral amines.

Hans Iding, Uwe T Bornscheuer, Paul Spurr, 2016, Nature chemistry.

Evaluation of 3′-phosphate as a transient protecting group for controlled enzymatic synthesis of DNA and XNA oligonucleotides

Irene Marzuoli, Kurt Püntener, Marie Flamme, 2022, Communications Chemistry.

Human FMO2-based microbial whole-cell catalysts for drug metabolite synthesis

Martina Geier, Beat Wirz, Matthias Kittelmann, 2015, Microbial Cell Factories.

2-phenylethylamine catabolism by Escherichia coli K-12: gene organization and expression.

R. Cooper, S. Hanlon, T. Hill, 1997, Microbiology.

formation for phenylethylamine oxidase expressed in Escherichia coli K-12

R. Cooper, S. Hanlon, 1995 .

Rapid characterization of the major drug-metabolizing human hepatic cytochrome P-450 enzymes expressed in Escherichia coli.

R J Riley, R. Riley, T. Friedberg, 1999, Drug metabolism and disposition: the biological fate of chemicals.

The Swiss Industrial Biocatalysis Consortium (SIBC): Past, Present and Future.

Steven Hanlon, S. Hanlon, 2020, Chimia.

Human flavin monooxygenase 2: Heterologous expression in E. coli and API modification

A. Glieder, M. Geier, S. Lütz, 2014 .

Recombinant Yeast and Bacteria that Express Human P450s: Bioreactors for Drug Discovery, Development, and Biotechnology

C. Wolf, T. Friedberg, O. Ghisalba, 2007 .

Merits and limitations of recombinant models for the study of human P450-mediated drug metabolism and toxicity: an intralaboratory comparison.

C. Wolf, B. Burchell, T. Friedberg, 1999, Drug metabolism reviews.

Towards the controlled enzymatic synthesis of LNA containing oligonucleotides

K. Pajuste, Serena Bisagni, Kurt Püntener, 2023, Frontiers in Chemistry.

Competition between cytochrome P-450 isozymes for NADPH-cytochrome P-450 oxidoreductase affects drug metabolism.

C. Wolf, B. Burchell, T. Friedberg, 1999, The Journal of pharmacology and experimental therapeutics.

Cellular location influences copper-dependent topaquinone formation for phenylethylamine oxidase expressed in Escherichia coli K-12.

R. Cooper, S. Hanlon, 1995, FEMS Microbiology Letters.

Formation in vitro of the 3,4,6-trihydroxyphenylalanine quinone cofactor.

R. Cooper, S. Hanlon, A. Hassan, 1995, The Biochemical journal.

Towards the enzymatic synthesis of phosphorothioate containing LNA oligonucleotides.

H. Iding, Marie Flamme, M. Hollenstein, 2021, Bioorganic & Medicinal Chemistry Letters.

The 44-kDa c-type cytochrome induced in Rhodobacter capsulatus during growth with dimethylsulphoxide as an electron acceptor is a cytochrome c peroxidase

A. McEwan, R. Holt, S. Hanlon, 1992 .

Human xanthine oxidase recombinant in E. coli: A whole cell catalyst for preparative drug metabolite synthesis.

Beat Wirz, Matthias Kittelmann, Margit Winkler, 2016, Journal of biotechnology.

Effective engineering of a ketoreductase for the biocatalytic synthesis of an ipatasertib precursor

D. Wetzl, H. Iding, S. Hanlon, 2024, Communications chemistry.