K. Sloan

J. Rautio, K. Sloan, Jussi Kärkkäinen, 2017, European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences.

Polyethylene Prodrugs Using Precisely Placed Pharmaceutical Agents

James K. Leonard, K. Wagener, D. Turek, 2010 .

Analgesic and Immunomodulatory Effects of Codeine and Codeine 6-glucuronide

I. Tebbett, J. Simpkins, D. Wielbo, 1996, Pharmaceutical Research.

The aminomethylation of adenine, cytosine and guanine

K. Sloan, K. G. Siver, 1984 .

Effect of vehicles on topical delivery of 5-fluorouracil (5FU) by 1-acyl-5FU prodrugs

H. Beall, K. Sloan, Ana I Patrick, 1997 .

Phenytoin prodrugs III: water-soluble prodrugs for oral and/or parenteral use.

S. Varia, V. Stella, K. Sloan, 1984, Journal of pharmaceutical sciences.

Mannich base derivatives of theophylline and 5-fluorouracil: syntheses, properties and topical delivery characteristics

K. Sloan, K. G. Siver, S. A. Koch, 1984 .

Acid-promoted aromatic substitution processes in photochemical and thermal decompositions of aryl azides

R. Sundberg, K. Sloan, 1973 .

Stereoselective synthesis of 2,4-bridged pyridinophanes☆

K. Sloan, W. Parham, J. B. Biasotti, 1971 .

13C NMR spectroscopy of 4,5- and 5,6-double bond isomers of spiro-3-steroidal ketone derivatives

N. Bodor, R. Little, K. Sloan, 1981 .

Acylation of the 4,5- and 5,6-double bond isomers of 3-steroidal thiazolidines: The chemical stability of spiro-3-steroidal 4,5- and 5,6-double bond isomers

N. Bodor, K. Sloan, J. Zupan, 1981 .

Synthesis of soft alkyl phenolic ether prodrugs using Mitsunobu chemistry

N. Bharti, J. Juntunen, S. Majumdar, 2006 .

Degradation of aspartame in acidic aqueous media and its stabilization by complexation with cyclodextrins or modified cyclodextrins

R. Prankerd, J. Perrin, K. Sloan, 1992 .

Microcalorimetric study of the interactions of aspartame with β-cyclodextrin and hydroxypropyl-β-cyclodextrin: The anamalous heat of dilution of the latter

R. Prankerd, J. Perrin, K. Sloan, 1992 .

Selection of a Proper Prodrug for Penetration Enhancement

Scott C. Wasdo, K. Sloan, Jennifer Synovec, 2015 .

Design for Optimized Topical Delivery: Prodrugs and a Paradigm Change

Kenneth B. Sloan, Jarkko Rautio, J. Rautio, 2006, Pharmaceutical Research.

The Role of Prodrugs in Penetration Enhancement

Scott C. Wasdo, K. Sloan, 2005 .

Transdermal delivery of theophylline from alcohol vehicles

H. Beall, K. Sloan, H. E. Taylor, 1998 .

The use of solubility parameters of drug and vehicle to describe skin transport

K. Sloan, 1990 .

Use of solubility parameters of drug and vehicle to predict flux through skin.

F. Flowers, K. Sloan, K. G. Siver, 1986, The Journal of investigative dermatology.

The effect of vehicle on the diffusion of salicylic acid through hairless mouse skin.

K. Sloan, K. G. Siver, S. A. Koch, 1986, Journal of pharmaceutical sciences.

Topical Delivery Using Prodrugs

Scott C. Wasdo, K. Sloan, 2007 .

α-(1H-Imidazol-1-yl)alkyl (IMIDA) carboxylic acid esters as prodrugs of carboxylic acid containing drugs

J. Juntunen, S. Majumdar, K. Sloan, 2007 .

Use of theoretical partition coefficients determined from solubility parameters to predict permeability coefficients for 5-fluorouracil.

E. F. Sherertz, K. Sloan, R. McTiernan, 1987, The Journal of investigative dermatology.

Imaging the prodrug-to-drug transformation of a 5-fluorouracil derivative in skin by confocal Raman microscopy.

Guojin Zhang, Richard Mendelsohn, Carol R Flach, 2007, The Journal of investigative dermatology.

Further reactions of 3‐hydroxy‐1(3H)‐isobenzofuranone with amines

K. Sloan, S. A. Koch, 1985 .

Prodrugs of 6-thiopurines: enhanced delivery through the skin.

N. Bodor, M. Hashida, T. Higuchi, 1983, Journal of pharmaceutical sciences.

1-Alkylcarbonyloxymethyl prodrugs of 5-fluorouracil (5-FU): synthesis, physicochemical properties, and topical delivery of 5-FU.

K. Sloan, H. E. Taylor, 1998, Journal of pharmaceutical sciences.

Prodrugs for dermal delivery

K. Sloan, 1989 .

IMPROVED DELIVERY THROUGH BIOLOGICAL MEMBRANES. 4. PRODRUGS OF L-DOPA

N. Bodor, T. Higuchi, K. Sloan, 1978 .

Regioselective synthesis of 2-O-acyl-3-O-(1-acyloxyalkyl) prodrugs of 5,6-isopropylidene-l-ascorbic acid

K. Sloan, Nikki A Thiele, J. Prybylski, 2016 .

Prodrugs of vitamin C: the reaction of 1-acyloxyalkyl-1-iodides with vitamin C 5,6-acetonide

K. Sloan, Nikki A Thiele, Jennifer McGowan, 2015 .

7-Alkylcarbonyloxymethyl prodrugs of theophylline: topical delivery of theophylline

Daniel J. Kerr, I. Tebbett, W. Roberts, 1998 .

Effect of aminomethyl (N-Mannich base) derivatization on the ability of S6-acetyloxymethyl-6-mercaptopurine prodrug to deliver 6-mercaptopurine through hairless mouse skin.

H. Beall, K. Sloan, A. Saab, 1989, Journal of pharmaceutical sciences.

Alkylation of 6-mercaptopurine (6-MP) with N-alkyl-N-alkoxycarbonylaminomethyl chlorides: S6-(N-alkyl-N-alkoxycarbonyl)aminomethyl-6-MP prodrug structure effect on the dermal delivery of 6-MP.

K. Sloan, K. G. Siver, 1990, Journal of pharmaceutical sciences.

The effect of structure of Mannich base prodrugs of 6-mercaptopurine on their ability to deliver 6-mercaptopurine through hairless mouse skin

K. Sloan, K. G. Siver, 1988 .

Effects of vehicles and prodrug properties and their interactions on the delivery of 6-mercaptopurine through skin: S6-acyloxymethyl-6-mercaptopurine prodrugs.

K. Sloan, R. Waranis, 1987, Journal of pharmaceutical sciences.

PRODRUGS OF 6-THIOPURINES: ENHANCED DELIVERY THROUGH THE SKIN

N. Bodor, M. Hashida, T. Higuchi, 1983 .

Effect of nucleophilicity and leaving group ability on the SN2 reactions of amines with (acyloxy)alkyl .alpha.-halides: a product distribution study

K. Sloan, S. A. Koch, 1983 .

Synthesis, hydrolyses and dermal delivery of N-alkyl-N-alkyloxycarbonylaminomethyl (NANAOCAM) derivatives of phenol, imide and thiol containing drugs.

S. Majumdar, K. Sloan, 2006, Bioorganic & medicinal chemistry letters.

Synthesis and topical delivery of N-alkyl-N-alkyloxycarbonylaminomethyl prodrugs of a model phenolic drug: acetaminophen.

S. Majumdar, K. Sloan, 2007, International journal of pharmaceutics.

Topical delivery of N-alkyl-N-alkyloxycarbonylaminomethyl (NANAOCAM) prodrugs of theophylline (ThH).

S. Majumdar, K. Sloan, 2007, International journal of pharmaceutics.

N-Alkyl-N-alkyloxycarbonylaminomethyl (NANAOCAM) prodrugs of carboxylic acid containing drugs.

S. Majumdar, K. Sloan, 2007, Bioorganic & medicinal chemistry letters.

Practical Synthesis of N‐Alkyl‐N‐alkyloxycarbonylaminomethyl Prodrug Derivatives of Acetaminophen, Theophylline, and 6‐Mercaptopurine

S. Majumdar, K. Sloan, 2006 .

Rational development of a soluble prodrug of a cytotoxic nucleoside: preparation and properties of arabinosyladenine 5'-formate.

N. Bodor, T. Higuchi, K. Sloan, 1975, Journal of pharmaceutical sciences.

N-Mannich-Base Prodrugs of 5-Iodo-2′-deoxycytidine as Topical Delivery Enhancers

K. Sloan, S. A. Koch, 1987, Pharmaceutical Research.

The reaction of heterocycle N-oxides with benzimidoyl chloride

K. Sloan, W. Parham, 1971 .

Secondary carbamate linker can facilitate the sustained release of dopamine from brain-targeted prodrug.

J. Rautio, K. Huttunen, K. Sloan, 2018, Bioorganic & medicinal chemistry letters.

Synthesis of 1‐ and 3‐arylcarbonyl derivatives of 5‐fluorouracil

R. Prankerd, J. Perrin, W. Underberg, 1999 .

1-Alkylcarbonyl-5-fluorouracil Prodrugs: Synthesis, Thermal and Hydrolytic Stability

R. Prankerd, H. Beall, K. Sloan, 1996 .

Reaction of alkylcarbonyloxymethyl halides with phenols: reevaluating the influence of steric hindrance

K. Sloan, J. Thomas, 2006 .

Synthesis of 3‐alkylcarbonyloxymethyl derivatives of 5‐fluorouracil

W. Roberts, K. Sloan, 2002 .

Soft drugs V: Thiazolidine-type derivatives of progesterone and testosterone.

N. Bodor, N Bodor, K B Sloan, 1982, Journal of pharmaceutical sciences.

Soft drugs 4. 3-Spirothiazolidines of hydrocortisone and its derivatives

Nicholas Bodor, Larry Caldwell, Kenneth B. Sloan, 1982 .

Acid-catalyzed rearrangements of the dihydroxyacetone side chain in steroids during ketal exchange

N. Bodor, R. Little, K. Sloan, 1978 .

Topical delivery of 5-fluorouracil (5-Fu) by 3-alkylcarbonyl-5-Fu prodrugs.

H. Beall, K. Sloan, 2001, International journal of pharmaceutics.

Topical Delivery of 5-Fluorouracil and 6-Mercaptopurine by Their Alkylcarbonyloxymethyl Prodrugs from Water: Vehicle Effects on Design of Prodrugs

Scott C. Wasdo, K. Sloan, R. Waranis, 2003, Pharmaceutical Research.

Application of the transformed Potts-Guy equation to in vivo human skin data.

W. Roberts, K. Sloan, 2001, Journal of pharmaceutical sciences.

1,3-Bisalkylcarbonyl- and 3-Alkylcarbonyl-5-fluorouracil Prodrugs: Syntheses, Thermal, and Hydrolytic Stability

R. Prankerd, H. Beall, K. Sloan, 1997 .

Transdermal delivery of 5-fluorouracil (5-FU) by 1-alkylcarbonyl-5-FU prodrugs

H. Beall, K. Sloan, 1996 .

Transdermal delivery of 5-fluorouracil (5-FU) through hairless mouse skin by 1-alkyloxycarbonyl-5-FU prodrugs: Physicochemical characterization of prodrugs and correlations with transdermal delivery

R. Prankerd, H. Beall, K. Sloan, 1994 .

The estimation of relative water solubility for prodrugs that are unstable in water

H. Beall, K. Sloan, J. Getz, 1993 .

Functional group considerations in the development of prodrug approaches to solving topical delivery problems

K. Sloan, 1992 .

The effect of receptor phase composition on the permeability of hairless mouse skin in diffusion cell experiments

H. Beall, K. Sloan, W. Weimar, 1991 .

The effect of structure of Mannich base prodrugs on their ability to deliver theophylline and 5-fluorouracil through hairless mouse skin

E. F. Sherertz, K. Sloan, R. McTiernan, 1988 .

Controlled delivery of theophylline: chemistry of 7-acyl- and 7,7'-acylditheophylline derivates.

N. Bodor, T. Higuchi, K. Sloan, 1978, Journal of pharmaceutical sciences.

A correlation of flux through a silicone membrane with flux through hairless mouse skin and human skin in vitro.

Scott C Wasdo, Scott C. Wasdo, J. Juntunen, 2009, International journal of pharmaceutics.

Transdermal delivery of 5-fluorouracil through skin of hairless mice and humans in vitro: a comparison of the effect of formulations and a prodrug

E. F. Sherertz, K. Sloan, R. McTiernan, 2004, Archives of Dermatological Research.

A comparison of the fit of flux through hairless mouse skin from water data to three model equations.

J. Juntunen, K. Sloan, H. Devarajan, 2009, International journal of pharmaceutics.

A surrogate for topical delivery in human skin: silicone membranes.

Hemamalini Ketha, K. Sloan, Jennifer Synovec, 2013, Therapeutic delivery.

The Flux of Phenolic Compounds through Silicone Membranes

K. Sloan, J. Prybylski, 2013, Pharmaceutics.

The solubility parameter of vehicles as a predictor of relative vehicle effects on the diffusion of 6-mercaptopurine

K. Sloan, K. G. Siver, R. Waranis, 1987 .

Modeling of flux through silicone membranes from water.

Scott C. Wasdo, J. Juntunen, K. Sloan, 2008, European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences.

A CONVENIENT SYNTHESIS OF (ACYLOXY)ALKYL α-ETHERS OF PHENOLS

N. Bodor, K. Sloan, J. Kaminski, 1984 .

Substrate-labelled fluorescence immunoassay of phenytoin.

S. Schulman, K. Sloan, J. S. O'Neal, 1986, Journal of pharmaceutical and biomedical analysis.

Flux through silicone and human skin fitted to a series/parallel model.

K. Sloan, J. Prybylski, 2014, Therapeutic delivery.

The effect of water solubility of solutes on their flux through human skin in vitro: an extended Flynn database fitted to the Roberts-Sloan equation.

Scott C. Wasdo, S. Majumdar, Antara Majumdar, 2007, International journal of pharmaceutics.

A Double Prodrug with Improved Membrane Permeability over the Parent Chelator HBED Provides Superior Cytoprotection against Hydrogen Peroxide

K. Sloan, Nikki A. Thiele, 2016, ChemMedChem.